ONTOLOGY REPORT - ANNOTATIONS
Term: delta DNA polymerase complex
Accession: GO:0043625
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Definition: A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair.
Synonyms: alt_id: GO:0005659
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Pold1
DNA polymerase delta 1, catalytic subunit
part_of
IC IDA IEA IBA ISO
GO_REF:0000117 GO_REF:0000033 GO_REF:0000114 (PMID:11595739), (PMID:12403614), (PMID:22465957)
UniProt GO_Central ComplexPortal RGD
PMID:11595739 PMID:12403614 PMID:22465957 PMID:7503737 PMID:10541966
GO_REF:0000033 GO_REF:0000114 GO_REF:0000117, RGD:2307013 , RGD:729526
NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465
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Pold2
DNA polymerase delta 2, accessory subunit
part_of
IC IDA IEA IBA ISO
GO_REF:0000117 GO_REF:0000033 GO_REF:0000114 (PMID:11595739), (PMID:12403614), (PMID:22465957)
UniProt GO_Central ComplexPortal RGD
PMID:11595739 PMID:12403614 PMID:22465957 PMID:7503737 PMID:10541966
GO_REF:0000033 GO_REF:0000114 GO_REF:0000117, RGD:2307013 , RGD:729526
NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160
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Pold3
DNA polymerase delta 3, accessory subunit
part_of
IC IBA ISO
GO_REF:0000033 GO_REF:0000114 (PMID:11595739), (PMID:12403614), (PMID:22465957)
GO_Central ComplexPortal RGD
PMID:11595739 PMID:12403614 PMID:22465957 PMID:7503737
GO_REF:0000033 GO_REF:0000114, RGD:2307013
NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665
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Pold4
DNA polymerase delta 4, accessory subunit
part_of
IC IBA ISO
GO_REF:0000033 GO_REF:0000114 (PMID:12403614)
GO_Central ComplexPortal RGD
PMID:12403614 PMID:7503737
GO_REF:0000033 GO_REF:0000114, RGD:2307013
NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401
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