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ONTOLOGY REPORT - ANNOTATIONS

Term:Ku70:Ku80 complex
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Accession:GO:0043564 term browser browse the term
Definition:Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.
Synonyms:exact_synonym: Ku70:Ku80 heterodimer


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Ku70:Ku80 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paxx PAXX, non-homologous end joining factor located_in ISO
IEA 		(PMID:25670504)
GO_REF:0000107 		RGD
Ensembl		 PMID:25670504 GO_REF:0000107 NCBI chr 3:8,274,762...8,276,322
Ensembl chr 3:28,672,906...28,674,466 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 part_of IBA
ISO
IEA 		GO_REF:0000033
(PMID:11493912), (PMID:20383123), (PMID:24095731), (PMID:26359349)
GO_REF:0000002 		GO_Central
RGD
InterPro		 PMID:11493912 PMID:20383123 PMID:24095731 PMID:26359349 GO_REF:0000002 GO_REF:0000033 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:81,375,863...81,493,293 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 part_of IBA
ISO
IEA 		GO_REF:0000033
(PMID:11493912), (PMID:20383123), (PMID:24095731), (PMID:26359349)
GO_REF:0000002
GO_REF:0000107 		GO_Central
RGD
InterPro
Ensembl		 PMID:11493912 PMID:20383123 PMID:24095731 PMID:26359349 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:115,422,662...115,443,884 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21544
    protein-containing complex 6918
      nuclear protein-containing complex 1363
        Ku70:Ku80 complex 3
Path 2
Term Annotations click to browse term
  cellular_component 21544
    cellular anatomical structure 21390
      organelle 14482
        membrane-bounded organelle 13071
          intracellular membrane-bounded organelle 12498
            nucleus 7903
              nuclear protein-containing complex 1363
                Ku70:Ku80 complex 3
paths to the root