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ONTOLOGY REPORT - ANNOTATIONS

Term:molybdopterin cofactor metabolic process
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Accession:GO:0043545 term browser browse the term
Definition:The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms:exact_synonym: Moco metabolic process;   Moco metabolism;   molybdopterin cofactor metabolism


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molybdopterin cofactor metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mocos molybdenum cofactor sulfurase involved_in ISO
IBA		 (PMID:11302742)
GO_REF:0000033		 RGD
GO_Central		 PMID:11302742 GO_REF:0000033 NCBI chr18:16,206,402...16,251,928
Ensembl chr18:15,931,654...15,977,187 		JBrowse link
G Mocs3 molybdenum cofactor synthesis 3 involved_in ISO (PMID:18650437) RGD PMID:18650437 NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890 		JBrowse link
G Nfs1 NFS1 cysteine desulfurase involved_in ISO (PMID:18650437) RGD PMID:18650437 NCBI chr 3:165,097,390...165,119,730
Ensembl chr 3:144,637,309...144,659,666 		JBrowse link
Mo-molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphn gephyrin involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 GO_REF:0000104
GO_REF:0000043
GO_REF:0000002
MGI:2182559 (PMID:9812897)
GO_REF:0000033
PMID:23163752		 UniProt
InterPro
RGD
GO_Central		 PMID:9812897 PMID:23163752 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000104, RGD:8554131 NCBI chr 6:102,687,405...103,216,679
Ensembl chr 6:96,892,148...97,483,612 		JBrowse link
G Mocos molybdenum cofactor sulfurase involved_in IEA GO_REF:0000104
GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 NCBI chr18:16,206,402...16,251,928
Ensembl chr18:15,931,654...15,977,187 		JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 involved_in ISO
IEA
IBA		 (PMID:15180982)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000043
GO_REF:0000033
(PMID:16021469), (PMID:9731530), (PMID:9921896)		 RGD
InterPro
Ensembl
UniProt
GO_Central		 PMID:9731530 PMID:9921896 PMID:15180982 PMID:16021469 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 NCBI chr 9:19,045,223...19,071,628
Ensembl chr 9:11,547,531...11,567,790 		JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:10053004), (PMID:12732628), (PMID:15073332), (PMID:16021469), (PMID:25709896)
GO_REF:0000104
GO_REF:0000107
GO_REF:0000002
GO_REF:0000043		 UniProt
RGD
Ensembl
InterPro		 PMID:10053004 PMID:12732628 PMID:15073332 PMID:16021469 PMID:25709896 GO_REF:0000002 GO_REF:0000024 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr 2:46,504,588...46,516,327
Ensembl chr 2:46,504,588...46,516,324 		JBrowse link
G Mocs3 molybdenum cofactor synthesis 3 involved_in ISO
IEA		 (PMID:15073332), (PMID:30817134)
GO_REF:0000043
GO_REF:0000104		 RGD
UniProt		 PMID:15073332 PMID:30817134 GO_REF:0000043 GO_REF:0000104 NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890 		JBrowse link
G Nfs1 NFS1 cysteine desulfurase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:165,097,390...165,119,730
Ensembl chr 3:144,637,309...144,659,666 		JBrowse link
molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphn gephyrin involved_in ISO
IEA		 (PMID:26613940), (PMID:9990024)
GO_REF:0000107
GO_REF:0000104
GO_REF:0000002
MGI:2182559 (PMID:12565882), (PMID:18411266)		 RGD
Ensembl
UniProt
InterPro		 PMID:9990024 PMID:12565882 PMID:18411266 PMID:26613940 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr 6:102,687,405...103,216,679
Ensembl chr 6:96,892,148...97,483,612 		JBrowse link
G Mocos molybdenum cofactor sulfurase involved_in ISO (PMID:35372998) RGD PMID:35372998 NCBI chr18:16,206,402...16,251,928
Ensembl chr18:15,931,654...15,977,187 		JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:17236133)
GO_REF:0000107
MGI:2659140 (PMID:12471057), (PMID:15862276), (PMID:17236133)		 RGD
Ensembl		 PMID:12471057 PMID:15862276 PMID:17236133 GO_REF:0000107 NCBI chr 9:19,045,223...19,071,628
Ensembl chr 9:11,547,531...11,567,790 		JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 involved_in ISO
IEA		 MGI:4881158 (PMID:27138983)
GO_REF:0000117		 RGD
UniProt		 PMID:27138983 GO_REF:0000117 NCBI chr 2:46,504,588...46,516,327
Ensembl chr 2:46,504,588...46,516,324 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        prosthetic group metabolic process 6
          molybdopterin cofactor metabolic process 6
            Mo-molybdopterin cofactor metabolic process + 6
            W-molybdopterin cofactor metabolic process + 0
            molybdopterin cofactor biosynthetic process + 6
            molybdopterin cofactor catabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        primary metabolic process 10745
          protein metabolic process 5212
            prosthetic group metabolic process 6
              molybdopterin cofactor metabolic process 6
                Mo-molybdopterin cofactor metabolic process + 6
                W-molybdopterin cofactor metabolic process + 0
                molybdopterin cofactor biosynthetic process + 6
                molybdopterin cofactor catabolic process + 0
paths to the root