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ONTOLOGY REPORT - ANNOTATIONS

Term:negative T cell selection
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Accession:GO:0043383 term browser browse the term
Definition:The process of elimination of immature T cells which react strongly with self-antigens.
Synonyms:exact_synonym: negative T lymphocyte selection


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negative T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G THEMIS thymocyte selection associated involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:127,696,628...127,918,595
Ensembl chr 6:127,708,072...127,918,631 		JBrowse link
negative thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIRE autoimmune regulator involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr21:44,285,876...44,298,648
Ensembl chr21:44,285,838...44,298,648 		JBrowse link
G ATG5 autophagy related 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,551,081...40,565,472 		JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,517...203,739,756 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175 		JBrowse link
G CD74 CD74 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969 		JBrowse link
G DOCK2 dedicator of cytokinesis 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:169,637,275...170,083,382
Ensembl chr 5:169,637,268...170,083,382 		JBrowse link
G FAS Fas cell surface death receptor acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:41,960,949...42,264,268
Ensembl chr 7:41,960,949...42,264,100 		JBrowse link
G MINK1 misshapen like kinase 1 acts_upstream_of_or_within ISO (PMID:15608642) MGI PMID:15608642 NCBI chr17:4,833,340...4,898,061
Ensembl chr17:4,833,340...4,898,061 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,759,342 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SPN sialophorin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:29,662,963...29,670,876
Ensembl chr16:29,662,979...29,670,876 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:97,713,576...97,756,364
Ensembl chr 2:97,713,576...97,744,327 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27142
    immune system process 3306
      T cell selection 70
        negative T cell selection 15
          negative extrathymic T cell selection 0
          negative thymic T cell selection 14
Path 2
Term Annotations click to browse term
  biological_process 27142
    developmental process 7762
      cellular developmental process 5253
        cell differentiation 5252
          cell development 3497
            hemopoiesis 1180
              leukocyte differentiation 755
                mononuclear cell differentiation 621
                  lymphocyte differentiation 509
                    T cell differentiation 377
                      T cell selection 70
                        negative T cell selection 15
                          negative extrathymic T cell selection 0
                          negative thymic T cell selection 14
paths to the root