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ONTOLOGY REPORT - ANNOTATIONS


Term:negative T cell selection
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Accession:GO:0043383 term browser browse the term
Definition:The process of elimination of immature T cells which react strongly with self-antigens.
Synonyms:exact_synonym: negative T lymphocyte selection



show annotations for term's descendants           Sort by:
negative T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Themis thymocyte selection associated involved_in ISO (PMID:19597498), (PMID:19597499) RGD PMID:19597498 PMID:19597499 NCBI chr 1:18,251,136...18,483,851
Ensembl chr 1:16,432,631...16,664,329
JBrowse link
negative thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1277186 (PMID:23382543)
GO_Central
RGD
PMID:23382543 GO_REF:0000033 NCBI chr20:10,635,775...10,650,709
Ensembl chr20:10,636,123...10,651,060
JBrowse link
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1338803|MGI:3612279 (PMID:23382543)
Ensembl
RGD
PMID:23382543 GO_REF:0000107 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (PMID:17785582) RGD PMID:17785582 NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:10429671) RGD PMID:10429671 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:7630421) RGD PMID:7630421 NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO MGI:1927205 (PMID:7679955) RGD PMID:7679955 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Dock2 dedicator of cytokinesis 2 acts_upstream_of_or_within ISO MGI:2152031 (PMID:12871644) RGD PMID:12871644 NCBI chr10:18,827,237...19,244,832
Ensembl chr10:18,827,239...19,244,808
JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO MGI:1856334 (PMID:10429671) RGD PMID:10429671 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (PMID:19667090) RGD PMID:19667090 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Mink1 misshapen-like kinase 1 acts_upstream_of_or_within ISO (PMID:15608642) RGD PMID:15608642 NCBI chr10:55,776,879...55,829,406
Ensembl chr10:55,278,391...55,330,782
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (PMID:8666928) RGD PMID:8666928 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:17227833)
Ensembl
UniProt
RGD
PMID:17227833 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO MGI:1857246 (PMID:10429671) RGD PMID:10429671 NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO MGI:2677447 (PMID:7630421) RGD PMID:7630421 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:38,989,750...39,011,700
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    immune system process 3112
      T cell selection 62
        negative T cell selection 15
          negative extrathymic T cell selection 0
          negative thymic T cell selection 14
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      cellular developmental process 4812
        cell differentiation 4811
          cell development 3339
            hemopoiesis 1079
              leukocyte differentiation 685
                mononuclear cell differentiation 549
                  lymphocyte differentiation 446
                    T cell differentiation 332
                      T cell selection 62
                        negative T cell selection 15
                          negative extrathymic T cell selection 0
                          negative thymic T cell selection 14
paths to the root