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ONTOLOGY REPORT - ANNOTATIONS


Term:memory T cell differentiation
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Accession:GO:0043379 term browser browse the term
Definition:The process in which a newly activated T cell acquires specialized features of a memory T cell.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: memory T lymphocyte differentiation
 related_synonym: memory T cell development



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memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tsc1 TSC complex subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2656240 (PMID:25271321)
Ensembl
RGD
PMID:25271321 GO_REF:0000107 NCBI chr 3:32,367,434...32,416,565 JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within ISO MGI:3582343 (PMID:29341118) RGD PMID:29341118 NCBI chr 4:13,710,566...13,716,207 JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:83,798,651...83,800,297 JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:12540904) RGD PMID:12540904 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:14688363) RGD PMID:14688363 NCBI chr 7:1,306,320...1,308,434 JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:29230018)
UniProt
RGD
PMID:29230018 GO_REF:0000024 NCBI chr 3:182,348,572...182,354,521 JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO (PMID:27591323) RGD PMID:27591323 NCBI chr20:4,513,464...4,518,457 JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:27591323) RGD PMID:27591323 NCBI chr20:4,548,664...4,558,237 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18713990) RGD PMID:18713990 NCBI chr13:76,256,654...76,280,133 JBrowse link
regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (PMID:15240675) RGD PMID:15240675 NCBI chr11:76,854,090...76,877,389 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    immune system process 3112
      immunological memory process 18
        immunological memory formation process 11
          memory T cell differentiation 10
            negative regulation of memory T cell differentiation 2
            positive regulation of memory T cell differentiation 6
            regulation of memory T cell differentiation + 9
Path 2
Term Annotations click to browse term
  biological_process 20534
    developmental process 7107
      cellular developmental process 4811
        cell differentiation 4810
          cell development 3338
            hemopoiesis 1078
              leukocyte differentiation 685
                mononuclear cell differentiation 549
                  lymphocyte differentiation 446
                    T cell differentiation 332
                      T cell differentiation involved in immune response 96
                        memory T cell differentiation 10
                          negative regulation of memory T cell differentiation 2
                          positive regulation of memory T cell differentiation 6
                          regulation of memory T cell differentiation + 9
paths to the root