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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of CD8-positive, alpha-beta T cell differentiation
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Accession:GO:0043377 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of CD8-positive, alpha-beta T cell differentiation;   downregulation of CD8-positive, alpha-beta T cell differentiation;   negative regulation of CD8-positive T lymphocyte differentiation;   negative regulation of CD8-positive T-cell differentiation;   negative regulation of CD8-positive, alpha beta T lymphocyte differentiation
 narrow_synonym: inhibition of CD8-positive, alpha-beta T cell differentiation
 related_synonym: negative regulation of CD8-positive, alpha-beta T cell development

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negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (PMID:24515893) UniProt PMID:24515893 NCBI chrNW_004936527:6,485,566...6,499,901
Ensembl chrNW_004936527:6,485,511...6,499,924 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936530:9,312,965...9,315,593
Ensembl chrNW_004936530:9,312,965...9,316,165 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:4,546,139...4,560,157
Ensembl chrNW_004936580:4,551,304...4,560,163 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17733
    immune system process 2393
      leukocyte activation 961
        lymphocyte activation 785
          T cell activation 554
            alpha-beta T cell activation 193
              CD8-positive, alpha-beta T cell activation 28
                CD8-positive, alpha-beta T cell differentiation 17
                  negative regulation of CD8-positive, alpha-beta T cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 17733
    cellular process 17274
      cellular developmental process 4463
        cell differentiation 4462
          cell development 3159
            hemopoiesis 1002
              leukocyte differentiation 644
                mononuclear cell differentiation 516
                  lymphocyte differentiation 421
                    T cell differentiation 315
                      alpha-beta T cell differentiation 143
                        CD8-positive, alpha-beta T cell differentiation 17
                          regulation of CD8-positive, alpha-beta T cell differentiation 6
                            negative regulation of CD8-positive, alpha-beta T cell differentiation 3
paths to the root