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ONTOLOGY REPORT - ANNOTATIONS

Term:beta selection
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Accession:GO:0043366 term browser browse the term
Definition:The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell.


show annotations for term's descendants           Sort by:
beta selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhoa ras homolog family member A involved_in ISO (PMID:25398325) RGD PMID:25398325 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO
IEA		 MGI:99613 (PMID:9275205)
GO_REF:0000107		 RGD
Ensembl		 PMID:9275205 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO
IEA		 MGI:99515 (PMID:9275205)
GO_REF:0000107		 RGD
Ensembl		 PMID:9275205 GO_REF:0000107 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:38,989,750...39,011,700 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    immune system process 3130
      T cell selection 62
        beta selection 3
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular developmental process 4833
        cell differentiation 4832
          cell development 3350
            hemopoiesis 1083
              leukocyte differentiation 690
                mononuclear cell differentiation 556
                  lymphocyte differentiation 453
                    T cell differentiation 335
                      alpha-beta T cell differentiation 151
                        beta selection 3
paths to the root