Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:cytotoxic T cell degranulation
go back to main search page
Accession:GO:0043316 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.
Synonyms:exact_synonym: cytotoxic T cell granule exocytosis;   cytotoxic T lymphocyte degranulation;   cytotoxic T lymphocyte granule exocytosis


show annotations for term's descendants           Sort by:
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO
IEA		 MGI:1856656 (PMID:11266473)
GO_REF:0000107		 RGD
Ensembl		 PMID:11266473 GO_REF:0000107 NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:73,782,694...73,847,829 		JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (PMID:23042080), (PMID:23190531) RGD PMID:23042080 PMID:23190531 NCBI chr 1:9,111,216...9,140,227
Ensembl chr 1:7,289,976...7,320,164 		JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:18424730)
GO_REF:0000024		 RGD
UniProt		 PMID:18424730 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    immune system process 3132
      immune effector process 847
        leukocyte degranulation 96
          cytotoxic T cell degranulation 4
            negative regulation of cytotoxic T cell degranulation 2
            positive regulation of cytotoxic T cell degranulation 0
            regulation of cytotoxic T cell degranulation + 2
Path 2
Term Annotations click to browse term
  biological_process 20567
    localization 5739
      establishment of localization 5084
        transport 4772
          export from cell 1130
            secretion by cell 1034
              exocytosis 412
                regulated exocytosis 281
                  leukocyte degranulation 96
                    cytotoxic T cell degranulation 4
                      negative regulation of cytotoxic T cell degranulation 2
                      positive regulation of cytotoxic T cell degranulation 0
                      regulation of cytotoxic T cell degranulation + 2
paths to the root