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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of leukocyte degranulation
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Accession:GO:0043302 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of leukocyte degranulation.
Synonyms:exact_synonym: positive regulation of immune cell degranulation;   positive regulation of leucocyte degranulation;   up regulation of leukocyte degranulation;   upregulation of leukocyte degranulation
 narrow_synonym: activation of leukocyte degranulation;   stimulation of leukocyte degranulation


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positive regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA 		(PMID:11714832)
GO_REF:0000107 		RGD
Ensembl		 PMID:11714832 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Stx4 syntaxin 4 involved_in ISO (PMID:16677249) RGD PMID:16677249 NCBI chr 1:191,880,549...191,890,333
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g3 phospholipase A2, group III involved_in ISO
IEA 		(PMID:23624557)
GO_REF:0000107 		RGD
Ensembl		 PMID:23624557 GO_REF:0000107 NCBI chr14:82,589,908...82,597,542
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Snx4 sorting nexin 4 involved_in ISO
IEA 		(PMID:18253931)
GO_REF:0000107 		RGD
Ensembl		 PMID:18253931 GO_REF:0000107 NCBI chr11:80,965,965...81,023,234
Ensembl chr11:67,460,870...67,518,174 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr12:21,842,206...21,958,556
Ensembl chr12:16,728,524...16,764,097 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18253931) 		Ensembl
RGD		 PMID:18253931 GO_REF:0000107 NCBI chr 4:106,000,570...106,011,081
Ensembl chr 4:104,442,393...104,452,897 		JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor acts_upstream_of_or_within ISO
IEA 		(PMID:11454903)
GO_REF:0000107 		RGD
Ensembl		 PMID:11454903 GO_REF:0000107 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Adora3 adenosine A3 receptor acts_upstream_of_or_within ISO MGI:2155986 (PMID:12817016) RGD PMID:12817016 NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:193,388,713...193,392,357 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IMP RGD PMID:18209484 RGD:5130941 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) RGD PMID:9000133 NCBI chr13:88,218,427...88,224,723
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO 		GO_REF:0000024
(PMID:21746961) 		UniProt
RGD		 PMID:21746961 GO_REF:0000024 NCBI chr 5:150,473,767...150,503,524
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Gab2 GRB2-associated binding protein 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:11449275) 		UniProt
RGD		 PMID:11449275 GO_REF:0000024 NCBI chr 1:160,841,066...161,036,940
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Gata1 GATA binding protein 1 IMP RGD PMID:22390417 RGD:9587812 NCBI chr  X:17,193,291...17,209,462
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gata2 GATA binding protein 2 IMP RGD PMID:22390417 RGD:9587812 NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Il13 interleukin 13 acts_upstream_of_or_within ISO MGI:1931804|MGI:96556 (PMID:15944273) RGD PMID:15944273 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO MGI:1857195|MGI:96541 (PMID:15944273) RGD PMID:15944273 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:1861951 (PMID:15944273) RGD PMID:15944273 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 IMP RGD PMID:16177098 RGD:1578516 NCBI chr 1:217,864,855...217,873,934
Ensembl chr 1:208,440,361...208,448,310 		JBrowse link
G Pld2 phospholipase D2 IMP RGD PMID:16861349 RGD:2299903 NCBI chr10:55,754,957...55,772,819
Ensembl chr10:55,256,359...55,272,808 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO
IEA 		(PMID:17346996)
GO_REF:0000107 		RGD
Ensembl		 PMID:17346996 GO_REF:0000107 NCBI chr 1:105,317,332...105,324,985
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Stxbp1 syntaxin binding protein 1 IMP RGD PMID:23487749 RGD:12904029 NCBI chr 3:36,474,428...36,536,120
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:23487749 RGD:12904029 NCBI chr12:6,487,265...6,498,351
Ensembl chr12:1,689,410...1,700,458 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within IMP
IEA
ISO 		GO_REF:0000107
MGI:2384078 (PMID:9000133) 		Ensembl
RGD		 PMID:9000133 PMID:16861349 GO_REF:0000107, RGD:2299903 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO
IEA 		(PMID:23632890)
GO_REF:0000107 		RGD
Ensembl		 PMID:23632890 GO_REF:0000107 NCBI chr19:54,654,101...54,740,586
Ensembl chr19:37,744,633...37,829,167 		JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:187,029,654...187,042,447
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) RGD PMID:21825173 NCBI chr 4:164,808,722...164,819,865
Ensembl chr 4:163,122,704...163,133,843 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO
IEA 		(PMID:23632890)
GO_REF:0000107 		RGD
Ensembl		 PMID:23632890 GO_REF:0000107 NCBI chr16:83,058,131...83,082,843
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,407,880...3,484,130 JBrowse link
positive regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd177 CD177 molecule involved_in ISO
IBA 		UniProtKB:P05107|UniProtKB:P11215 (PMID:21193407)
GO_REF:0000033 		RGD
GO_Central		 PMID:21193407 GO_REF:0000033 NCBI chr 1:89,467,926...89,488,490
Ensembl chr 1:80,340,034...80,360,621 		JBrowse link
G Cd177l1 CD177 molecule like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:89,416,086...89,421,699
Ensembl chr 1:80,288,194...80,293,484 		JBrowse link
G Cd177l2 CD177 molecule like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:89,451,755...89,456,377
Ensembl chr 1:80,323,863...80,328,311 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO
IEA 		UniProtKB:P05107|UniProtKB:Q8N6Q3 (PMID:21193407)
GO_REF:0000107 		RGD
Ensembl		 PMID:21193407 GO_REF:0000107 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgb2 integrin subunit beta 2 involved_in ISO
IEA 		UniProtKB:P11215|UniProtKB:Q8N6Q3 (PMID:21193407)
GO_REF:0000107 		RGD
Ensembl		 PMID:21193407 GO_REF:0000107 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Lypd10 Ly6/PLAUR domain containing 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:89,400,914...89,406,146
Ensembl chr 1:80,273,019...80,278,219 		JBrowse link
G Lypd10l1 Ly6/PLAUR domain containing 10 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:89,436,460...89,440,884
Ensembl chr 1:80,308,643...80,312,222 		JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:2829894 RGD:10041060 NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    immune system process 3133
      immune effector process 847
        positive regulation of immune effector process 320
          positive regulation of leukocyte degranulation 37
            positive regulation of basophil degranulation 0
            positive regulation of cytotoxic T cell degranulation 0
            positive regulation of eosinophil degranulation 2
            positive regulation of mast cell degranulation + 22
            positive regulation of natural killer cell degranulation 5
            positive regulation of neutrophil degranulation 8
Path 2
Term Annotations click to browse term
  biological_process 20543
    localization 5729
      establishment of localization 5079
        transport 4766
          secretion 1232
            secretion by cell 1034
              exocytosis 412
                regulated exocytosis 281
                  leukocyte degranulation 96
                    regulation of leukocyte degranulation 57
                      positive regulation of leukocyte degranulation 37
                        positive regulation of basophil degranulation 0
                        positive regulation of cytotoxic T cell degranulation 0
                        positive regulation of eosinophil degranulation 2
                        positive regulation of mast cell degranulation + 22
                        positive regulation of natural killer cell degranulation 5
                        positive regulation of neutrophil degranulation 8
paths to the root