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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of leukocyte degranulation
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Accession:GO:0043301 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of leukocyte degranulation.
Synonyms:exact_synonym: down regulation of leukocyte degranulation;   downregulation of leukocyte degranulation;   negative regulation of immune cell degranulation;   negative regulation of leucocyte degranulation
 narrow_synonym: inhibition of leukocyte degranulation



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negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
negative regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:14662900)
BHF-UCL
RGD
PMID:14662900 GO_REF:0000024 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in
acts_upstream_of_or_within
ISO (PMID:16339535)
(PMID:12874256)
RGD PMID:12874256 PMID:16339535 NCBI chr10:100,428,826...100,441,693
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Cd84 CD84 molecule involved_in ISO
IEA
(PMID:22068234)
GO_REF:0000107
RGD
Ensembl
PMID:22068234 GO_REF:0000107 NCBI chr13:86,859,979...86,899,984
Ensembl chr13:84,327,553...84,362,076
JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO
IEA
MGI:2179135 (PMID:18421012)
GO_REF:0000107
RGD
Ensembl
PMID:18421012 GO_REF:0000107 NCBI chr19:66,062,635...66,066,427
Ensembl chr19:49,153,699...49,157,738
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 acts_upstream_of_or_within ISO MGI:2653910 (PMID:15944273) RGD PMID:15944273 NCBI chr  X:115,814,620...115,886,080
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO
IEA
MGI:3051384 (PMID:15235600)
GO_REF:0000107
RGD
Ensembl
PMID:15235600 GO_REF:0000107 NCBI chr12:32,096,338...32,139,949
Ensembl chr12:26,460,175...26,503,744
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,407,880...3,484,130 JBrowse link
negative regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO MGI:88141 (PMID:19703997) RGD PMID:19703997 NCBI chr10:61,760,743...61,959,526
Ensembl chr10:61,262,516...61,461,505
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO MGI:107771 (PMID:19703997) RGD PMID:19703997 NCBI chr20:13,468,732...13,596,333
Ensembl chr20:13,471,668...13,597,016
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO
IEA
(PMID:30911105)
GO_REF:0000107
RGD
Ensembl
PMID:30911105 GO_REF:0000107 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:77,073,012...77,092,393
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    immune system process 3130
      immune effector process 844
        negative regulation of immune effector process 153
          negative regulation of leukocyte degranulation 14
            negative regulation of basophil degranulation 0
            negative regulation of cytotoxic T cell degranulation 2
            negative regulation of eosinophil degranulation 1
            negative regulation of mast cell degranulation 7
            negative regulation of natural killer cell degranulation 2
            negative regulation of neutrophil degranulation 3
Path 2
Term Annotations click to browse term
  biological_process 20558
    localization 5728
      establishment of localization 5075
        transport 4763
          secretion 1229
            secretion by cell 1031
              exocytosis 412
                regulated exocytosis 281
                  leukocyte degranulation 96
                    regulation of leukocyte degranulation 57
                      negative regulation of leukocyte degranulation 14
                        negative regulation of basophil degranulation 0
                        negative regulation of cytotoxic T cell degranulation 2
                        negative regulation of eosinophil degranulation 1
                        negative regulation of mast cell degranulation 7
                        negative regulation of natural killer cell degranulation 2
                        negative regulation of neutrophil degranulation 3
paths to the root