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ONTOLOGY REPORT - ANNOTATIONS

Term:apoptosome
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Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota


show annotations for term's descendants           Sort by:
apoptosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 part_of IDA
IEA
ISO		 GO_REF:0000107
(PMID:10206961), (PMID:21827945)
PMID:26265044
GO_REF:0000002		 Ensembl
RGD
InterPro		 PMID:10206961 PMID:21827945 PMID:17483091 PMID:26265044 GO_REF:0000002 GO_REF:0000107, RGD:2325744, RGD:11079191 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Casp9 caspase 9 part_of ISO
IEA		 (PMID:10206961), (PMID:21827945)
GO_REF:0000107		 RGD
Ensembl		 PMID:10206961 PMID:21827945 GO_REF:0000107 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Casp9_v1 caspase-9-carboxyl-terminal divergent part_of IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Cycs cytochrome c, somatic part_of ISO (PMID:10206961) RGD PMID:10206961 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats part_of ISO (PMID:15271982) RGD PMID:15271982 NCBI chr 8:70,155,059...70,243,416
Ensembl chr 8:61,259,477...61,347,789 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21364
    protein-containing complex 6830
      apoptosome 5
Path 2
Term Annotations click to browse term
  cellular_component 21364
    cellular anatomical structure 21069
      intracellular anatomical structure 15590
        cytoplasm 12298
          cytosol 4535
            apoptosome 5
paths to the root