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ONTOLOGY REPORT - ANNOTATIONS

Term:Fanconi anaemia nuclear complex
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Accession:GO:0043240 term browser browse the term
Definition:A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.
Synonyms:exact_synonym: FA complex;   FA core complex;   FA nuclear complex;   Fanconi anaemia complex

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Fanconi anaemia nuclear complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CENPS centromere protein S part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:121,333,554...121,343,893
Ensembl chr20:121,340,995...121,353,902
Ensembl chr20:121,340,995...121,353,902 		JBrowse link
G CENPX centromere protein X part_of IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:73,905,670...73,910,622
Ensembl chr16:73,905,600...73,910,322 		JBrowse link
G FAAP20 FA core complex associated protein 20 part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:129,357,043...129,373,409
Ensembl chr20:129,357,089...129,362,518 		JBrowse link
G FAAP24 FA core complex associated protein 24 part_of IEA Ensembl
InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:28,012,664...28,018,612
Ensembl chr 6:28,012,808...28,019,627 		JBrowse link
G FANCA FA complementation group A part_of IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:75,073,161...75,149,110
Ensembl chr 5:75,073,358...75,148,591 		JBrowse link
G FANCB FA complementation group B part_of IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:13,321,304...13,352,368
Ensembl chr  X:13,321,527...13,342,478 		JBrowse link
G FANCC FA complementation group C part_of IEA Ensembl
InterPro
UniProt
TreeGrafter		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr12:107,780,087...107,991,828
Ensembl chr12:107,845,135...107,991,237 		JBrowse link
G FANCE FA complementation group E part_of ISO (PMID:20347428), (PMID:22266823) UniProt PMID:20347428 PMID:22266823 NCBI chr17:36,659,266...36,671,274 JBrowse link
G FANCE FA complementation group E part_of IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 Ensembl chr17:36,659,169...36,667,784 JBrowse link
G FANCF FA complementation group F part_of IEA Ensembl
InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:42,377,150...42,381,653
Ensembl chr 1:42,378,883...42,380,007 		JBrowse link
G FANCG FA complementation group G part_of IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr12:45,537,817...45,544,038
Ensembl chr12:45,538,303...45,543,766 		JBrowse link
G FANCL FA complementation group L part_of IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr14:48,725,447...48,803,892
Ensembl chr14:48,725,541...48,805,356 		JBrowse link
G FANCM FA complementation group M part_of IEA Ensembl GO_REF:0000107 NCBI chr24:22,255,750...22,327,191
Ensembl chr24:22,256,236...22,329,609 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20992
    protein-containing complex 8111
      nuclear protein-containing complex 2688
        Fanconi anaemia nuclear complex 13
Path 2
Term Annotations click to browse term
  cellular_component 20992
    cellular anatomical structure 20606
      organelle 15383
        membrane-bounded organelle 13832
          intracellular membrane-bounded organelle 13272
            nucleus 9075
              nuclear protein-containing complex 2688
                Fanconi anaemia nuclear complex 13
paths to the root