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ONTOLOGY REPORT - ANNOTATIONS

Term:myelin maintenance
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Accession:GO:0043217 term browser browse the term
Definition:The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath.
Synonyms:exact_synonym: myelin sheath maintenance


show annotations for term's descendants           Sort by:
myelin maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 involved_in ISO (PMID:11875044), (PMID:15489218) RGD PMID:11875044 PMID:15489218 NCBI chr  X:156,579,669...156,601,448
Ensembl chr  X:151,428,578...151,450,115 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:15489218)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:15489218 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:124,142,597...124,191,202
Ensembl chr 7:122,263,032...122,311,642 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 involved_in ISO (PMID:20534485) RGD PMID:20534485 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 involved_in ISO
ISS 		(PMID:30620337), (PMID:30620338)
GO_REF:0000024 		RGD
UniProt		 PMID:30620337 PMID:30620338 GO_REF:0000024 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 involved_in ISO (PMID:21966409) RGD PMID:21966409 NCBI chr 9:116,502,864...116,707,274
Ensembl chr 9:109,016,113...109,260,607 		JBrowse link
central nervous system myelin maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin involved_in ISO
ISS
IEA 		(PMID:21543606)
GO_REF:0000024
GO_REF:0000107 		RGD
Alzheimers_University_of_Toronto
Ensembl		 PMID:21543606 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Fa2h fatty acid 2-hydroxylase acts_upstream_of_or_within ISO
IEA 		MGI:3829000|MGI:4430585 (PMID:18815260), (PMID:21491498)
GO_REF:0000107 		RGD
Ensembl		 PMID:18815260 PMID:21491498 GO_REF:0000107 NCBI chr19:56,222,240...56,273,480
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Myrf myelin regulatory factor involved_in IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:22956843) 		GO_Central
Ensembl
RGD		 PMID:22956843 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:216,279,057...216,311,155
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:18082964) RGD PMID:18082964 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
peripheral nervous system myelin maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 acts_upstream_of_or_within ISO
IEA 		(PMID:20448149)
GO_REF:0000107 		RGD
Ensembl		 PMID:20448149 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 acts_upstream_of_or_within ISO
IEA 		(PMID:20448149)
GO_REF:0000107 		RGD
Ensembl		 PMID:20448149 GO_REF:0000107 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Fa2h fatty acid 2-hydroxylase acts_upstream_of_or_within ISO
IEA 		MGI:3829000 (PMID:18815260)
GO_REF:0000107 		RGD
Ensembl		 PMID:18815260 GO_REF:0000107 NCBI chr19:56,222,240...56,273,480
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15082788) 		Ensembl
RGD		 PMID:15082788 GO_REF:0000107 NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member involved_in ISO
IEA 		(PMID:20237282)
GO_REF:0000107 		RGD
Ensembl		 PMID:20237282 GO_REF:0000107 NCBI chr 6:97,548,133...97,654,163
Ensembl chr 6:97,548,630...97,653,305 		JBrowse link
G Plec plectin involved_in ISO
IEA 		MGI:3721885 (PMID:23836526)
GO_REF:0000107 		RGD
Ensembl		 PMID:23836526 GO_REF:0000107 NCBI chr 7:109,768,447...109,829,798
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Prx periaxin involved_in IBA
ISO 		GO_REF:0000033
(PMID:10839370) 		GO_Central
RGD		 PMID:10839370 GO_REF:0000033 NCBI chr 1:82,785,082...82,807,154
Ensembl chr 1:82,786,815...82,807,407 		JBrowse link
G Sh3tc2 SH3 domain and tetratricopeptide repeats 2 acts_upstream_of_or_within ISO
IEA 		MGI:4367025 (PMID:19805030)
GO_REF:0000107 		RGD
Ensembl		 PMID:19805030 GO_REF:0000107 NCBI chr18:57,686,701...57,747,735
Ensembl chr18:55,416,413...55,483,083 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within 		ISS
ISO
IEA 		GO_REF:0000024
MGI:1857872 (PMID:10433959)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:10433959 GO_REF:0000024 GO_REF:0000107 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      ensheathment of neurons 199
        axon ensheathment 199
          myelination 197
            myelin maintenance 17
              central nervous system myelin maintenance 4
              peripheral nervous system myelin maintenance 9
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            nervous system development 2881
              ensheathment of neurons 199
                axon ensheathment 199
                  myelination 197
                    myelin maintenance 17
                      central nervous system myelin maintenance 4
                      peripheral nervous system myelin maintenance 9
paths to the root