ONTOLOGY REPORT - ANNOTATIONS
Term: axon initial segment
Accession: GO:0043194
browse the term
Definition: Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.
Synonyms: exact_synonym: initial segment
xref: NIF_Subcellular:sao256000789
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Adam22
ADAM metallopeptidase domain 22
IDA
MMO:0000538
RGD
PMID:30598502
RGD:153298976
NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
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Ank3
ankyrin 3
located_in
IDA ISO IEA IMP
(PMID:11724816), (PMID:20877009), (PMID:25950943), (PMID:26671463), (PMID:27356871) GO_REF:0000107 PMID:28426968 (PMID:27356871)
RGD Ensembl
PMID:11724816 PMID:20877009 PMID:25950943 PMID:26671463 PMID:27356871 PMID:21551097 PMID:11724816 PMID:28426968 PMID:25950943 More...
GO_REF:0000107, RGD:6767287 , RGD:8553674 , RGD:13514087 , RGD:13800538
NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
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Bcan
brevican
IDA
MMO:0000538
RGD
PMID:17709431
RGD:14392774
NCBI chr 2:173,454,479...173,467,717
Ensembl chr 2:173,454,482...173,467,460
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Bin1
bridging integrator 1
located_in
IDA
PMID:9182667
Alzheimers_University_of_Toronto
PMID:9182667
RGD:8553847
NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
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Camk2d
calcium/calmodulin-dependent protein kinase II delta
located_in
ISO
(PMID:20877009)
RGD
PMID:20877009
NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
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Cck
cholecystokinin
IDA
nonpyramidal neurons in the basolateral amygdalar complex after colchicine treatment
RGD
PMID:12763251
RGD:1626094
NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
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Clcn2
chloride voltage-gated channel 2
located_in
IDA
PMID:11068136
UniProt
PMID:11068136
RGD:405650339
NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657
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Cnga3
cyclic nucleotide gated channel subunit alpha 3
IDA
RGD
PMID:18434027
RGD:6902905
NCBI chr 9:39,447,534...39,494,044
Ensembl chr 9:39,448,034...39,493,183
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Cntn2
contactin 2
located_in is_active_in
IEA ISO
GO_REF:0000107 (PMID:18509034)
Ensembl RGD
PMID:18509034
GO_REF:0000107
NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887
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Cntnap2
contactin associated protein 2
is_active_in
ISO
(PMID:18509034)
RGD
PMID:18509034
NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027
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Dlg2
discs large MAGUK scaffold protein 2
is_active_in
ISO
MGI:2388036 (PMID:18509034)
RGD
PMID:18509034
NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475
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Kcna1
potassium voltage-gated channel subfamily A member 1
is_active_in
ISO
(PMID:18509034)
RGD
PMID:18509034
NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682
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Kcna2
potassium voltage-gated channel subfamily A member 2
is_active_in
ISO
(PMID:18509034)
RGD
PMID:18509034
NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400
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Kcna4
potassium voltage-gated channel subfamily A member 4
located_in is_active_in
IEA ISO
GO_REF:0000107 (PMID:18509034)
Ensembl RGD
PMID:18509034
GO_REF:0000107
NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162
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Kcnab2
potassium voltage-gated channel subfamily A regulatory beta subunit 2
is_active_in
ISO
(PMID:18509034)
RGD
PMID:18509034
NCBI chr 5:162,899,511...162,988,057
Ensembl chr 5:162,901,896...162,988,243
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Kcnq2
potassium voltage-gated channel subfamily Q member 2
located_in is_active_in
IDA ISO
MMO:0000662 (PMID:16525039) (PMID:14762142), (PMID:24333508)
RGD
PMID:14762142 PMID:16525039 PMID:24333508 PMID:17311847
RGD:153344585
NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
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Kcnq3
potassium voltage-gated channel subfamily Q member 3
located_in is_active_in
IDA ISO IBA IEA
(PMID:16525039) (PMID:14762142), (PMID:24333508) GO_REF:0000033 GO_REF:0000107
RGD GO_Central Ensembl
PMID:14762142 PMID:16525039 PMID:24333508 PMID:24333508
GO_REF:0000033 GO_REF:0000107, RGD:9686369
NCBI chr 7:97,730,219...98,025,652
Ensembl chr 7:97,730,465...98,025,653
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Lgi1
leucine-rich, glioma inactivated 1
IDA
MMO:0000538
RGD
PMID:30598502
RGD:153298976
NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616
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Lrrc7
leucine rich repeat containing 7
is_active_in
IDA IBA
GO_REF:0000033
GO_Central RGD
PMID:8824323
GO_REF:0000033, RGD:1299511
NCBI chr 2:247,146,616...247,634,945
Ensembl chr 2:247,147,752...247,634,547
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Map1a
microtubule-associated protein 1A
located_in
ISO
(PMID:25788676)
RGD
PMID:25788676
NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
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Map2
microtubule-associated protein 2
located_in
IDA ISO
PMID:28426968 (PMID:28426968)
RGD
PMID:28426968 PMID:28426968
RGD:13514087
NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
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Nav1
neuron navigator 1
is_active_in located_in
IBA ISO
GO_REF:0000033 (PMID:26671463)
GO_Central RGD
PMID:26671463
GO_REF:0000033
NCBI chr13:46,866,972...47,119,368
Ensembl chr13:46,873,689...47,126,449
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Nfasc
neurofascin
located_in
IDA ISO
(PMID:26671463) PMID:28426968 PMID:11724816 PMID:27356871
RGD
PMID:26671463 PMID:22649224 PMID:28426968 PMID:11724816 PMID:27356871
RGD:12904752 , RGD:13514087 , RGD:8553674 , RGD:12793037
NCBI chr13:43,997,223...44,183,863
Ensembl chr13:43,997,224...44,183,880
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Nrcam
neuronal cell adhesion molecule
located_in
IDA
MMO:0000538 PMID:11724816
RGD BHF-UCL
PMID:17709431 PMID:11724816
RGD:14392774 , RGD:8553674
NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
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Scn1a
sodium voltage-gated channel alpha subunit 1
located_in
IEA ISO
GO_REF:0000107 (PMID:17537961)
Ensembl RGD
PMID:17537961
GO_REF:0000107
NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699
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Scn2a
sodium voltage-gated channel alpha subunit 2
IDA
RGD
PMID:12036953
RGD:625497
NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214
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Scn2b
sodium voltage-gated channel beta subunit 2
is_active_in
IDA
PMID:22992729
UniProt
PMID:22992729
RGD:405866198
NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765
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Scn8a
sodium voltage-gated channel alpha subunit 8
located_in
IDA
PMID:11724816
BHF-UCL
PMID:11724816
RGD:8553674
NCBI chr 7:131,982,152...132,156,075
Ensembl chr 7:131,982,480...132,151,292
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Sptbn4
spectrin, beta, non-erythrocytic 4
located_in
IDA ISO
MMO:0000538 (PMID:20877009), (PMID:26671463) PMID:28426968 PMID:11086001
RGD
PMID:20877009 PMID:26671463 PMID:17709431 PMID:28426968 PMID:11086001
RGD:14392774 , RGD:13514087 , RGD:8553353
NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228
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Trim46
tripartite motif-containing 46
located_in
IEA ISO
GO_REF:0000107 (PMID:26671463)
Ensembl RGD
PMID:26671463
GO_REF:0000107
NCBI chr 2:174,641,494...174,654,237
Ensembl chr 2:174,641,496...174,654,141
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