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ONTOLOGY REPORT - ANNOTATIONS

Term:axon initial segment
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Accession:GO:0043194 term browser browse the term
Definition:Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.
Synonyms:exact_synonym: initial segment
 xref: NIF_Subcellular:sao256000789


show annotations for term's descendants           Sort by:
axon initial segment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam22 ADAM metallopeptidase domain 22 IDA MMO:0000538 RGD PMID:30598502 RGD:153298976 NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:26,671,112...26,925,843 		JBrowse link
G Ank3 ankyrin 3 located_in IDA
IMP
ISO 		PMID:25950943
(PMID:27356871)
PMID:28426968
PMID:11724816
(PMID:11724816), (PMID:20877009), (PMID:25950943), (PMID:26671463), (PMID:27356871) 		RGD PMID:11724816 PMID:20877009 PMID:25950943 PMID:26671463 PMID:27356871 More... RGD:6767287, RGD:13800538, RGD:13514087, RGD:8553674 NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879 		JBrowse link
G Bcan brevican IDA MMO:0000538 RGD PMID:17709431 RGD:14392774 NCBI chr 2:175,752,333...175,765,766
Ensembl chr 2:175,752,336...175,765,314 		JBrowse link
G Bin1 bridging integrator 1 located_in IDA PMID:9182667 Alzheimers_University_of_Toronto PMID:9182667 RGD:8553847 NCBI chr18:24,282,840...24,341,461
Ensembl chr18:24,283,801...24,341,458 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta located_in ISO (PMID:20877009) RGD PMID:20877009 NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276 		JBrowse link
G Cck cholecystokinin IDA nonpyramidal neurons in the basolateral amygdalar complex after colchicine treatment RGD PMID:12763251 RGD:1626094 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686 		JBrowse link
G Clcn2 chloride voltage-gated channel 2 located_in IDA PMID:11068136 UniProt PMID:11068136 RGD:405650339 NCBI chr11:93,702,382...93,716,059
Ensembl chr11:93,702,360...93,716,059 		JBrowse link
G Cnga3 cyclic nucleotide gated channel subunit alpha 3 IDA RGD PMID:18434027 RGD:6902905 NCBI chr 9:46,943,353...46,989,862
Ensembl chr 9:46,928,810...46,989,862 		JBrowse link
G Cntn2 contactin 2 is_active_in ISO
IEA 		(PMID:18509034)
GO_REF:0000107 		RGD
Ensembl		 PMID:18509034 GO_REF:0000107 NCBI chr13:46,497,269...46,528,112
Ensembl chr13:46,499,396...46,528,027 		JBrowse link
G Cntnap2 contactin associated protein 2 is_active_in ISO (PMID:18509034) RGD PMID:18509034 NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:75,109,858...77,366,258 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 is_active_in ISO MGI:2388036 (PMID:18509034) RGD PMID:18509034 NCBI chr 1:153,864,545...155,916,238
Ensembl chr 1:153,865,299...155,916,215 		JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 is_active_in ISO (PMID:18509034) RGD PMID:18509034 NCBI chr 4:161,150,378...161,160,051
Ensembl chr 4:161,147,418...161,160,044 		JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 is_active_in ISO
IEA 		(PMID:18509034)
GO_REF:0000107 		RGD
Ensembl		 PMID:18509034 GO_REF:0000107 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:197,392,698...197,407,519 		JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 is_active_in ISO (PMID:18509034) RGD PMID:18509034 NCBI chr 3:114,211,091...114,218,545
Ensembl chr 3:114,210,998...114,344,932 		JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 is_active_in ISO (PMID:18509034) RGD PMID:18509034 NCBI chr 5:162,899,511...162,988,057
Ensembl chr 5:168,184,613...168,270,760 		JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 is_active_in
located_in 		IDA
ISO 		MMO:0000662
(PMID:14762142), (PMID:24333508)
(PMID:16525039) 		RGD PMID:14762142 PMID:16525039 PMID:24333508 PMID:17311847 RGD:153344585 NCBI chr 3:188,572,345...188,631,391
Ensembl chr 3:188,572,926...188,631,302 		JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 located_in
is_active_in 		IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
(PMID:14762142), (PMID:24333508)
(PMID:16525039) 		Ensembl
GO_Central
RGD		 PMID:14762142 PMID:16525039 PMID:24333508 PMID:24333508 GO_REF:0000033 GO_REF:0000107, RGD:9686369 NCBI chr 7:99,614,089...99,914,736
Ensembl chr 7:99,619,544...99,914,610 		JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 IDA MMO:0000538 RGD PMID:30598502 RGD:153298976 NCBI chr 1:245,455,691...245,497,036
Ensembl chr 1:245,455,599...245,499,095 		JBrowse link
G Lrrc7 leucine rich repeat containing 7 is_active_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:8824323 GO_REF:0000033, RGD:1299511 NCBI chr 2:249,792,441...250,294,267
Ensembl chr 2:249,805,448...250,293,718 		JBrowse link
G Map1a microtubule-associated protein 1A located_in ISO (PMID:25788676) RGD PMID:25788676 NCBI chr 3:128,716,907...128,736,638
Ensembl chr 3:128,716,940...128,740,159 		JBrowse link
G Map2 microtubule-associated protein 2 located_in IDA
ISO 		PMID:28426968
(PMID:28426968) 		RGD PMID:28426968 PMID:28426968 RGD:13514087 NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459 		JBrowse link
G Nav1 neuron navigator 1 is_active_in
located_in 		IBA
ISO 		GO_REF:0000033
(PMID:26671463) 		GO_Central
RGD		 PMID:26671463 GO_REF:0000033 NCBI chr13:49,418,755...49,671,117
Ensembl chr13:49,418,755...49,671,004 		JBrowse link
G Nfasc neurofascin located_in IDA
ISO
IEA 		PMID:27356871
PMID:11724816
PMID:28426968
(PMID:26671463)
GO_REF:0000117 		RGD
UniProt		 PMID:26671463 PMID:22649224 PMID:27356871 PMID:11724816 PMID:28426968 GO_REF:0000117, RGD:12904752, RGD:12793037, RGD:8553674, RGD:13514087 NCBI chr13:46,549,369...46,735,989
Ensembl chr13:46,549,369...46,736,139 		JBrowse link
G Nrcam neuronal cell adhesion molecule located_in IDA
IEA 		MMO:0000538
PMID:11724816
GO_REF:0000117 		UniProt
RGD		 PMID:17709431 PMID:11724816 GO_REF:0000117, RGD:14392774, RGD:8553674 NCBI chr 6:67,129,723...67,425,510
Ensembl chr 6:67,129,801...67,430,539 		JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 located_in IEA
ISO 		GO_REF:0000107
(PMID:17537961) 		Ensembl
RGD		 PMID:17537961 GO_REF:0000107 NCBI chr 3:71,360,840...71,479,870
Ensembl chr 3:71,360,841...71,479,791 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 IDA RGD PMID:12036953 RGD:625497 NCBI chr 3:70,710,862...70,845,569
Ensembl chr 3:70,710,954...70,845,279 		JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 is_active_in IDA PMID:22992729 UniProt PMID:22992729 RGD:405866198 NCBI chr 8:54,322,383...54,334,519
Ensembl chr 8:54,322,383...54,334,519 		JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 located_in IDA PMID:11724816 BHF-UCL PMID:11724816 RGD:8553674 NCBI chr 7:133,860,901...134,034,809
Ensembl chr 7:133,861,227...134,030,026 		JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 located_in IDA
ISO
IEA 		MMO:0000538
PMID:28426968
PMID:11086001
(PMID:20877009), (PMID:26671463)
GO_REF:0000107 		RGD
Ensembl		 PMID:20877009 PMID:26671463 PMID:17709431 PMID:28426968 PMID:11086001 GO_REF:0000107, RGD:14392774, RGD:13514087, RGD:8553353 NCBI chr 1:91,778,379...91,865,970
Ensembl chr 1:91,778,380...91,865,049 		JBrowse link
G Trim46 tripartite motif-containing 46 located_in IEA
ISO 		GO_REF:0000107
(PMID:26671463) 		Ensembl
RGD		 PMID:26671463 GO_REF:0000107 NCBI chr 2:176,939,253...176,952,285
Ensembl chr 2:176,939,253...176,958,364 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21544
    cellular anatomical structure 21390
      axon initial segment 30
Path 2
Term Annotations click to browse term
  cellular_component 21544
    cellular anatomical structure 21390
      cell projection 2891
        plasma membrane bounded cell projection 2784
          neuron projection 1656
            axon 893
              main axon 94
                axon initial segment 30
paths to the root