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ONTOLOGY REPORT - ANNOTATIONS


Term:axon initial segment
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Accession:GO:0043194 term browser browse the term
Definition:Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.
Synonyms:exact_synonym: initial segment
 xref: NIF_Subcellular:sao256000789



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axon initial segment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam22 ADAM metallopeptidase domain 22 IDA MMO:0000538 RGD PMID:30598502 RGD:153298976 NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
JBrowse link
G Ank3 ankyrin 3 located_in IDA
ISO
IEA
IMP
(PMID:11724816), (PMID:20877009), (PMID:25950943), (PMID:26671463), (PMID:27356871)
GO_REF:0000107
PMID:28426968
(PMID:27356871)
RGD
Ensembl
PMID:11724816 PMID:20877009 PMID:25950943 PMID:26671463 PMID:27356871 More... GO_REF:0000107, RGD:6767287, RGD:8553674, RGD:13514087, RGD:13800538 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Bcan brevican IDA MMO:0000538 RGD PMID:17709431 RGD:14392774 NCBI chr 2:173,454,479...173,467,717
Ensembl chr 2:173,454,482...173,467,460
JBrowse link
G Bin1 bridging integrator 1 located_in IDA PMID:9182667 Alzheimers_University_of_Toronto PMID:9182667 RGD:8553847 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta located_in ISO (PMID:20877009) RGD PMID:20877009 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Cck cholecystokinin IDA nonpyramidal neurons in the basolateral amygdalar complex after colchicine treatment RGD PMID:12763251 RGD:1626094 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Clcn2 chloride voltage-gated channel 2 located_in IDA PMID:11068136 UniProt PMID:11068136 RGD:405650339 NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657
JBrowse link
G Cnga3 cyclic nucleotide gated channel subunit alpha 3 IDA RGD PMID:18434027 RGD:6902905 NCBI chr 9:39,447,534...39,494,044
Ensembl chr 9:39,448,034...39,493,183
JBrowse link
G Cntn2 contactin 2 located_in
is_active_in
IEA
ISO
GO_REF:0000107
(PMID:18509034)
Ensembl
RGD
PMID:18509034 GO_REF:0000107 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887
JBrowse link
G Cntnap2 contactin associated protein 2 is_active_in ISO (PMID:18509034) RGD PMID:18509034 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 is_active_in ISO MGI:2388036 (PMID:18509034) RGD PMID:18509034 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475
JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 is_active_in ISO (PMID:18509034) RGD PMID:18509034 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 is_active_in ISO (PMID:18509034) RGD PMID:18509034 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400
JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 located_in
is_active_in
IEA
ISO
GO_REF:0000107
(PMID:18509034)
Ensembl
RGD
PMID:18509034 GO_REF:0000107 NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162
JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 is_active_in ISO (PMID:18509034) RGD PMID:18509034 NCBI chr 5:162,899,511...162,988,057
Ensembl chr 5:162,901,896...162,988,243
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 located_in
is_active_in
IDA
ISO
MMO:0000662
(PMID:16525039)
(PMID:14762142), (PMID:24333508)
RGD PMID:14762142 PMID:16525039 PMID:24333508 PMID:17311847 RGD:153344585 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 located_in
is_active_in
IDA
ISO
IBA
IEA
(PMID:16525039)
(PMID:14762142), (PMID:24333508)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:14762142 PMID:16525039 PMID:24333508 PMID:24333508 GO_REF:0000033 GO_REF:0000107, RGD:9686369 NCBI chr 7:97,730,219...98,025,652
Ensembl chr 7:97,730,465...98,025,653
JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 IDA MMO:0000538 RGD PMID:30598502 RGD:153298976 NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616
JBrowse link
G Lrrc7 leucine rich repeat containing 7 is_active_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:8824323 GO_REF:0000033, RGD:1299511 NCBI chr 2:247,146,616...247,634,945
Ensembl chr 2:247,147,752...247,634,547
JBrowse link
G Map1a microtubule-associated protein 1A located_in ISO (PMID:25788676) RGD PMID:25788676 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
JBrowse link
G Map2 microtubule-associated protein 2 located_in IDA
ISO
PMID:28426968
(PMID:28426968)
RGD PMID:28426968 PMID:28426968 RGD:13514087 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Nav1 neuron navigator 1 is_active_in
located_in
IBA
ISO
GO_REF:0000033
(PMID:26671463)
GO_Central
RGD
PMID:26671463 GO_REF:0000033 NCBI chr13:46,866,972...47,119,368
Ensembl chr13:46,873,689...47,126,449
JBrowse link
G Nfasc neurofascin located_in IDA
ISO
(PMID:26671463)
PMID:28426968
PMID:11724816
PMID:27356871
RGD PMID:26671463 PMID:22649224 PMID:28426968 PMID:11724816 PMID:27356871 RGD:12904752, RGD:13514087, RGD:8553674, RGD:12793037 NCBI chr13:43,997,223...44,183,863
Ensembl chr13:43,997,224...44,183,880
JBrowse link
G Nrcam neuronal cell adhesion molecule located_in IDA MMO:0000538
PMID:11724816
RGD
BHF-UCL
PMID:17709431 PMID:11724816 RGD:14392774, RGD:8553674 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 located_in IEA
ISO
GO_REF:0000107
(PMID:17537961)
Ensembl
RGD
PMID:17537961 GO_REF:0000107 NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 IDA RGD PMID:12036953 RGD:625497 NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 is_active_in IDA PMID:22992729 UniProt PMID:22992729 RGD:405866198 NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 located_in IDA PMID:11724816 BHF-UCL PMID:11724816 RGD:8553674 NCBI chr 7:131,982,152...132,156,075
Ensembl chr 7:131,982,480...132,151,292
JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 located_in IDA
ISO
MMO:0000538
(PMID:20877009), (PMID:26671463)
PMID:28426968
PMID:11086001
RGD PMID:20877009 PMID:26671463 PMID:17709431 PMID:28426968 PMID:11086001 RGD:14392774, RGD:13514087, RGD:8553353 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228
JBrowse link
G Trim46 tripartite motif-containing 46 located_in IEA
ISO
GO_REF:0000107
(PMID:26671463)
Ensembl
RGD
PMID:26671463 GO_REF:0000107 NCBI chr 2:174,641,494...174,654,237
Ensembl chr 2:174,641,496...174,654,141
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20969
    cellular anatomical structure 20770
      axon initial segment 30
Path 2
Term Annotations click to browse term
  cellular_component 20969
    cellular anatomical structure 20770
      cell projection 2663
        plasma membrane bounded cell projection 2570
          neuron projection 1627
            axon 868
              main axon 93
                axon initial segment 30
paths to the root