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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of macrophage activation
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Accession:GO:0043032 term browser browse the term
Definition:Any process that stimulates, induces or increases the rate of macrophage activation.
Synonyms:exact_synonym: positive regulation of macrophage polarization;   up regulation of macrophage activation;   upregulation of macrophage activation
 narrow_synonym: activation of macrophage activation;   stimulation of macrophage activation



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positive regulation of macrophage activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1d1 CD1d1 molecule acts_upstream_of_or_within ISO (PMID:21460847) RGD PMID:21460847 NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha involved_in ISO (PMID:21131957) RGD PMID:21131957 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO (PMID:22383698) RGD PMID:22383698 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO UniProtKB:O08573 (PMID:20937702) RGD PMID:20937702 NCBI chr10:31,383,801...31,415,334
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:17164250) RGD PMID:17164250 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Il10 interleukin 10 IDA RGD PMID:25837415 RGD:11049473 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 involved_in ISO (PMID:19841166) RGD PMID:19841166 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19841166)
Ensembl
RGD
PMID:19841166 GO_REF:0000107 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il33 interleukin 33 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:19841166)
(PMID:26936882)
GO_REF:0000107
RGD
Ensembl
PMID:19841166 PMID:26936882 GO_REF:0000107 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4r interleukin 4 receptor involved_in ISO (PMID:19841166) RGD PMID:19841166 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO
GO_REF:0000024
(PMID:27439214), (PMID:27443879)
UniProt
RGD
PMID:27439214 PMID:27443879 GO_REF:0000024 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit IMP RGD PMID:18443593 RGD:2293336 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kars1 lysyl-tRNA synthetase 1 involved_in ISO
IBA
(PMID:15851690)
GO_REF:0000033
RGD
GO_Central
PMID:15851690 GO_REF:0000033 NCBI chr19:39,957,846...39,976,837
Ensembl chr19:39,957,846...39,977,632
JBrowse link
G Lbp lipopolysaccharide binding protein involved_in IDA
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000107
(PMID:8409400)
GO_Central
Ensembl
RGD
PMID:8409400 PMID:10733550 GO_REF:0000033 GO_REF:0000107, RGD:9685188 NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lgals9 galectin 9 involved_in ISO UniProtKB:Q8VIM0 (PMID:20937702) RGD PMID:20937702 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Mir145 microRNA 145 acts_upstream_of ISO (PMID:30634164) RGD PMID:30634164 NCBI chr18:57,369,983...57,370,070
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Pla2g4a phospholipase A2 group 4A involved_in IEA
ISO
GO_REF:0000107
(PMID:9403692), (PMID:9403693)
Ensembl
RGD
PMID:9403692 PMID:9403693 GO_REF:0000107 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18757424) RGD PMID:18757424 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:Q9Y2C9 (PMID:20037584)
Ensembl
RGD
PMID:20037584 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO UniProtKB:O00206 (PMID:20037584) RGD PMID:20037584 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (PMID:16633345) RGD PMID:16633345 NCBI chr14:80,452,936...80,470,141
Ensembl chr14:76,228,371...76,275,265
JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 1:3,506,106...3,527,982 JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA
(PMID:18174455)
GO_REF:0000107
RGD
Ensembl
PMID:18174455 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234
JBrowse link
positive regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO (PMID:28251676) RGD PMID:28251676 NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 IMP RGD PMID:21750563 RGD:329955444 NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:22302802 RGD:13462052 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:25049354)
Ensembl
RGD
PMID:25049354 GO_REF:0000107 NCBI chr 8:13,008,873...13,018,729
Ensembl chr 8:4,724,029...4,733,520
JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (PMID:19100238) RGD PMID:19100238 NCBI chr14:22,301,278...22,336,218
Ensembl chr14:21,952,496...21,981,245
JBrowse link
G Tafa3 TAFA chemokine like family member 3 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:25595455)
GO_Central
RGD
PMID:25595455 GO_REF:0000033 NCBI chr 2:192,264,153...192,280,356
Ensembl chr 2:192,267,093...192,274,019
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO
IBA
(PMID:24990881)
(PMID:24990881), (PMID:25631124), (PMID:29752066), (PMID:30617257), (PMID:31370707)
GO_REF:0000033
RGD
GO_Central
PMID:24990881 PMID:25631124 PMID:29752066 PMID:30617257 PMID:31370707 GO_REF:0000033 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Ttbk1 tau tubulin kinase 1 involved_in ISO (PMID:19118186) RGD PMID:19118186 NCBI chr 9:14,493,166...14,538,372
Ensembl chr 9:14,493,389...14,535,774
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    immune system process 3112
      leukocyte activation 1069
        positive regulation of leukocyte activation 356
          positive regulation of macrophage activation 31
            positive regulation of microglial cell activation 8
Path 2
Term Annotations click to browse term
  biological_process 20536
    biological regulation 13822
      regulation of biological process 13376
        regulation of cellular process 13014
          regulation of cell activation 663
            regulation of leukocyte activation 606
              positive regulation of leukocyte activation 356
                positive regulation of macrophage activation 31
                  positive regulation of microglial cell activation 8
paths to the root