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ONTOLOGY REPORT - ANNOTATIONS


Term:fibrinolysis
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Accession:GO:0042730 term browser browse the term
Definition:A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.
Synonyms:xref: Reactome:R-HSA-75205 "Dissolution of Fibrin Clot";   Wikipedia:Fibrinolysis



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fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3028929 (PMID:14702107)
Ensembl
RGD
PMID:14702107 GO_REF:0000107 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Cpb2 carboxypeptidase B2 involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:11848438 GO_REF:0000033, RGD:632532 NCBI chr15:56,967,128...57,015,964
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G F12 coagulation factor XII involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G F2 coagulation factor II, thrombin involved_in ISO
IEA
(PMID:12855810)
GO_REF:0000107
RGD
Ensembl
PMID:12855810 GO_REF:0000107 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IBA
(PMID:16846481)
GO_REF:0000033
RGD
GO_Central
PMID:16846481 GO_REF:0000033 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:12855810) RGD PMID:12855810 NCBI chr10:55,831,901...55,856,729
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Hrg histidine-rich glycoprotein involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000043
MGI:3789962 (PMID:15869579)
UniProt
RGD
PMID:15869579 GO_REF:0000043 NCBI chr11:91,559,087...91,573,982
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:91,543,964...91,553,946
Ensembl chr11:78,039,376...78,049,353
JBrowse link
G Klkb1 kallikrein B1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:53,690,180...53,714,570
Ensembl chr16:46,958,707...46,982,053
JBrowse link
G Plau plasminogen activator, urokinase involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000107
(PMID:9733098)
GO_Central
Ensembl
RGD
PMID:9733098 GO_REF:0000033 GO_REF:0000107 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plg plasminogen involved_in ISO
IEA
(PMID:14688145), (PMID:17307854), (PMID:22025510)
GO_REF:0000104
RGD
UniProt
PMID:14688145 PMID:17307854 PMID:22025510 GO_REF:0000104 NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Pros1 protein S involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:13,676,310...13,757,858
Ensembl chr11:230,696...311,286
JBrowse link
G Serping1 serpin family G member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO
IEA
(PMID:14726399)
GO_REF:0000107
RGD
Ensembl
PMID:14726399 GO_REF:0000107 NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Cpb2 carboxypeptidase B2 IDA RGD PMID:17002650 RGD:2313647 NCBI chr15:56,967,128...57,015,964
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Hrg histidine-rich glycoprotein involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:3789962 (PMID:15869579)
GO_Central
RGD
PMID:15869579 GO_REF:0000033 NCBI chr11:91,559,087...91,573,982
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:91,543,964...91,553,946
Ensembl chr11:78,039,376...78,049,353
JBrowse link
G Plg plasminogen involved_in ISO (PMID:14726399) RGD PMID:14726399 NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA
(PMID:2503541)
GO_REF:0000107
RGD
Ensembl
PMID:2503541 GO_REF:0000107 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinf2 serpin family F member 2 involved_in IMP
ISO
(PMID:134998) RGD PMID:134998 PMID:6506034 RGD:1625541 NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:53,720,502...53,741,547
Ensembl chr16:46,986,107...47,008,437
JBrowse link
G F12 coagulation factor XII involved_in IEA
ISO
GO_REF:0000107
(PMID:89876)
Ensembl
RGD
PMID:89876 GO_REF:0000107 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G Klkb1 kallikrein B1 involved_in ISO
IEA
(PMID:89876)
GO_REF:0000107
RGD
Ensembl
PMID:89876 GO_REF:0000107 NCBI chr16:53,690,180...53,714,570
Ensembl chr16:46,958,707...46,982,053
JBrowse link
G Plg plasminogen involved_in ISO (PMID:26667841), (PMID:6438154) RGD PMID:6438154 PMID:26667841 NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 TAS RGD PMID:11739291 RGD:1578383 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:16480936) RGD PMID:16480936 NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,310,977...93,356,329
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    negative regulation of biological process 5819
      negative regulation of hemostasis 47
        negative regulation of blood coagulation 46
          fibrinolysis 20
            negative regulation of fibrinolysis 8
            positive regulation of fibrinolysis 4
            regulation of fibrinolysis + 12
Path 2
Term Annotations click to browse term
  biological_process 20553
    biological regulation 13833
      regulation of biological process 13387
        regulation of response to stimulus 4328
          regulation of response to stress 1475
            regulation of response to wounding 190
              regulation of wound healing 140
                regulation of blood coagulation 65
                  negative regulation of blood coagulation 46
                    fibrinolysis 20
                      negative regulation of fibrinolysis 8
                      positive regulation of fibrinolysis 4
                      regulation of fibrinolysis + 12
paths to the root