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ONTOLOGY REPORT - ANNOTATIONS

Term:ATPase-coupled transmembrane transporter activity
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Accession:GO:0042626 term browser browse the term
Definition:Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.
Synonyms:exact_synonym: ATP-coupled transmembrane transporter activity;   ATP-dependent transmembrane transporter activity;   ATPase activity, coupled to transmembrane movement of substances
 narrow_synonym: hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
 broad_synonym: ATPase activity, coupled to movement of substances;   P-P-bond-hydrolysis-driven transmembrane transporter activity;   P-P-bond-hydrolysis-driven transporter
 alt_id: GO:0015405;   GO:0016820;   GO:0043492
 xref: EC:7.2.2.-;   Reactome:R-HSA-1467457 "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region";   Reactome:R-HSA-2161506 "abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate";   Reactome:R-HSA-2161538 "abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate";   Reactome:R-HSA-9033499 "PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol";   Reactome:R-HSA-9033505 "PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12";   Reactome:R-HSA-9659680 "ABCB1 transports xenobiotics out of the cell";   Reactome:R-HSA-9750546 "ABCC4 transports TPMP substrates from cytosol to extracellular region";   Reactome:R-HSA-9750617 "ABCC5 transports TPMP substrates from cytosol to extracellular region";   Reactome:R-HSA-9753278 "ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3";   Reactome:R-HSA-9753283 "ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3";   Reactome:R-HSA-9753284 "ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region";   Reactome:R-HSA-9759454 "ABCB1 transports PREDN,PREDL out of kidney cells";   Reactome:R-HSA-9759461 "ABCB1 transports PREDN,PREDL out of hepatic cells";   Reactome:R-HSA-9794120 "ABCG2 transports Cipro from intestinal cell to extracellular space";   Reactome:R-HSA-9794572 "ABCG2 transports Cipro from hepatic cell to extracellular space"

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ATPase-coupled transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO RGD PMID:12909583 RGD:1304419 NCBI chrNW_004955419:21,553,863...21,681,626
Ensembl chrNW_004955419:21,553,835...21,681,619 		JBrowse link
G Abcb1 ATP binding cassette subfamily B member 1 enables ISO (MGI:5770073|PMID:17709369)
(PMID:17709369)
(PMID:28757552)		 Reactome
ARUK-UCL		 PMID:17709369 PMID:28757552 MGI:5770073 NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 enables ISO (PMID:11500505) UniProt PMID:11500505 NCBI chrNW_004955507:5,724,788...5,791,281
Ensembl chrNW_004955507:5,724,762...5,790,812 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 enables ISO (PMID:19334674)
PMID:10362653		 ARUK-UCL
MGI		 PMID:10362653 PMID:19334674 RGD:8553810 NCBI chrNW_004955451:11,087,246...11,130,108
Ensembl chrNW_004955451:11,087,570...11,130,482 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 (PEL blood group) enables ISO (PMID:15364914), (PMID:15454390) UniProt PMID:15364914 PMID:15454390 NCBI chrNW_004955404:14,700,808...14,927,944
Ensembl chrNW_004955404:14,700,808...14,928,617 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 enables ISO (PMID:11880368) UniProt PMID:11880368 NCBI chrNW_004955442:865,292...921,739
Ensembl chrNW_004955442:865,238...922,221 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 enables ISO (PMID:26181369) ARUK-UCL PMID:26181369 NCBI chrNW_004955413:17,385,966...17,510,220
Ensembl chrNW_004955413:17,382,564...17,510,132 		JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 enables ISO (PMID:29397936) UniProt PMID:29397936 NCBI chrNW_004955580:459,715...475,363
Ensembl chrNW_004955580:459,715...475,774 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 enables ISO (PMID:16946495), (PMID:29397936) UniProt PMID:16946495 PMID:29397936 NCBI chrNW_004955505:717,800...769,702
Ensembl chrNW_004955505:721,222...798,470 		JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 enables ISO (PMID:29397936) UniProt PMID:29397936 NCBI chrNW_004955423:280,497...359,711
Ensembl chrNW_004955423:280,497...359,711 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (JR blood group) enables ISO (PMID:28554189), (PMID:30405239) UniProt PMID:28554189 PMID:30405239 NCBI chrNW_004955474:12,365,903...12,408,715 JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 enables ISO (PMID:27144356) UniProt PMID:27144356 NCBI chrNW_004955441:10,964,588...10,987,771
Ensembl chrNW_004955441:10,964,858...10,986,967 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 enables ISO (PMID:27144356) UniProt PMID:27144356 NCBI chrNW_004955441:10,982,307...11,004,789
Ensembl chrNW_004955441:10,982,307...11,009,116 		JBrowse link
G Ralbp1 ralA binding protein 1 enables ISO (PMID:10924126) UniProt PMID:10924126 NCBI chrNW_004955402:2,571,672...2,616,040
Ensembl chrNW_004955402:2,569,637...2,616,040 		JBrowse link
ABC-type bile acid transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 enables ISO (PMID:18985798), (PMID:32203132)
PMID:15901796
(PMID:15791618), (PMID:15901796)		 UniProt PMID:15791618 PMID:15901796 PMID:18985798 PMID:32203132 RGD:1598579 RGD:30309919 NCBI chrNW_004955449:5,412,958...5,511,629
Ensembl chrNW_004955449:5,412,876...5,512,701 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 enables ISO PMID:10644759 UniProt PMID:10644759 RGD:40902972 NCBI chrNW_004955451:11,087,246...11,130,108
Ensembl chrNW_004955451:11,087,570...11,130,482 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 (PEL blood group) enables ISO (PMID:16282361) UniProt PMID:16282361 NCBI chrNW_004955404:14,700,808...14,927,944
Ensembl chrNW_004955404:14,700,808...14,928,617 		JBrowse link
ABC-type fatty-acyl-CoA transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 enables ISO (PMID:15682271)
(PMID:18757502)		 UniProt PMID:15682271 PMID:18757502 NCBI chrNW_004955580:459,715...475,363
Ensembl chrNW_004955580:459,715...475,774 		JBrowse link
ABC-type glutathione S-conjugate transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) enables ISO (MGI:1099361|PMID:9359705) UniProt PMID:9359705 MGI:1099361 NCBI chrNW_004955442:729,322...858,826
Ensembl chrNW_004955442:729,316...860,290 		JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 enables ISO (PMID:23087055) UniProt PMID:23087055 NCBI chrNW_004955437:9,278,977...9,297,618
Ensembl chrNW_004955437:9,280,050...9,297,314 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 enables ISO (PMID:10220572) UniProt PMID:10220572 RGD:42721988 NCBI chrNW_004955507:5,724,788...5,791,281
Ensembl chrNW_004955507:5,724,762...5,790,812 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 enables ISO (PMID:15083066) UniProt PMID:15083066 NCBI chrNW_004955451:11,087,246...11,130,108
Ensembl chrNW_004955451:11,087,570...11,130,482 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 (PEL blood group) enables ISO (PMID:17959747) UniProt PMID:17959747 NCBI chrNW_004955404:14,700,808...14,927,944
Ensembl chrNW_004955404:14,700,808...14,928,617 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 enables ISO (PMID:11880368) UniProt PMID:11880368 NCBI chrNW_004955442:865,292...921,739
Ensembl chrNW_004955442:865,238...922,221 		JBrowse link
ABC-type heme transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 (LAN blood group) enables ISO (PMID:17006453) UniProt PMID:17006453 NCBI chrNW_004955453:14,215,104...14,222,338
Ensembl chrNW_004955453:14,215,408...14,222,172 		JBrowse link
ABC-type iron-sulfur cluster transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 enables ISO (PMID:33157103) UniProt PMID:33157103 NCBI chrNW_004955562:1,079,884...1,220,806
Ensembl chrNW_004955562:1,077,198...1,221,061 		JBrowse link
ABC-type oligopeptide transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb9 ATP binding cassette subfamily B member 9 enables ISO (PMID:15863492), (PMID:25646430), (PMID:30877195), (PMID:31417173) UniProt PMID:15863492 PMID:25646430 PMID:30877195 PMID:31417173 NCBI chrNW_004955482:5,817,334...5,838,642
Ensembl chrNW_004955482:5,817,334...5,837,220 		JBrowse link
ABC-type peptide antigen transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tap1 transporter 1, ATP binding cassette subfamily B member enables ISO (PMID:25656091)
(PMID:11133832), (PMID:25377891)
(MGI:5767072|PMID:12645939), (MGI:5767079|PMID:8342042)		 UniProt
Reactome		 PMID:8342042 PMID:11133832 PMID:12645939 PMID:25377891 PMID:25656091 MGI:5767072 MGI:5767079 NCBI chrNW_004955437:1,504,549...1,511,110
Ensembl chrNW_004955437:1,504,947...1,511,097 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member enables ISO (PMID:25377891)
(PMID:1538751), (PMID:25656091)		 UniProt PMID:1538751 PMID:25377891 PMID:25656091 NCBI chrNW_004955437:1,480,217...1,499,032
Ensembl chrNW_004955437:1,477,341...1,498,575 		JBrowse link
ABC-type peptide transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb9 ATP binding cassette subfamily B member 9 enables ISO (PMID:17977821), (PMID:18434309), (PMID:22641697) UniProt PMID:17977821 PMID:18434309 PMID:22641697 NCBI chrNW_004955482:5,817,334...5,838,642
Ensembl chrNW_004955482:5,817,334...5,837,220 		JBrowse link
ABC-type sterol transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 enables ISO (PMID:17408620) BHF-UCL PMID:17408620 NCBI chrNW_004955407:39,410,262...39,459,383
Ensembl chrNW_004955407:39,410,262...39,459,383 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 enables ISO (MGI:3047008|PMID:15210959)
(PMID:15210959)		 UniProt PMID:15210959 MGI:3047008 NCBI chrNW_004955412:20,256,467...20,270,172
Ensembl chrNW_004955412:20,256,293...20,271,278 		JBrowse link
ABC-type transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 (LAN blood group) enables ISO (PMID:23792964)
(PMID:27507172)
(PMID:22294697)
(MGI:5424330|PMID:22294697)
(MGI:5898211|PMID:27507172)		 UniProt PMID:22294697 PMID:23792964 PMID:27507172 MGI:5424330 MGI:5898211 NCBI chrNW_004955453:14,215,104...14,222,338
Ensembl chrNW_004955453:14,215,408...14,222,172 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) enables ISO (PMID:7961706), (PMID:9281595) UniProt PMID:7961706 PMID:9281595 NCBI chrNW_004955442:729,322...858,826
Ensembl chrNW_004955442:729,316...860,290 		JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 enables ISO (PMID:23087055) UniProt PMID:23087055 NCBI chrNW_004955437:9,278,977...9,297,618
Ensembl chrNW_004955437:9,280,050...9,297,314 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 enables ISO (PMID:17540771) MGI PMID:17540771 NCBI chrNW_004955420:23,447,920...23,522,732
Ensembl chrNW_004955420:23,447,920...23,522,732 		JBrowse link
ABC-type vitamin B12 transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) enables ISO (PMID:21511966), (PMID:22547309)
(PMID:19897579)		 Reactome
MGI		 PMID:19897579 PMID:21511966 PMID:22547309 NCBI chrNW_004955442:729,322...858,826
Ensembl chrNW_004955442:729,316...860,290 		JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 enables ISO (PMID:33845046) UniProt PMID:33845046 NCBI chrNW_004955523:1,170,306...1,181,352
Ensembl chrNW_004955523:1,170,303...1,182,467 		JBrowse link
ABC-type xenobiotic transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 enables ISO (PMID:26903515) UniProt PMID:26903515 NCBI chrNW_004955442:14,933,550...14,989,492
Ensembl chrNW_004955442:14,933,550...14,989,492 		JBrowse link
G Abcb1 ATP binding cassette subfamily B member 1 enables ISO (PMID:28260112)
(PMID:28411377)
(PMID:23893241)
(PMID:26850595), (PMID:28757552)		 ARUK-UCL PMID:23893241 PMID:26850595 PMID:28260112 PMID:28411377 PMID:28757552 NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 enables ISO (PMID:18245269) UniProt PMID:18245269 RGD:30309924 NCBI chrNW_004955449:5,412,958...5,511,629
Ensembl chrNW_004955449:5,412,876...5,512,701 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO estrone 3-sulfate transport RGD PMID:12867490 PMID:12893836 RGD:2303048 RGD:2303061 NCBI chrNW_004955442:729,322...858,826
Ensembl chrNW_004955442:729,316...860,290 		JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 enables ISO (PMID:23087055) UniProt PMID:23087055 NCBI chrNW_004955437:9,278,977...9,297,618
Ensembl chrNW_004955437:9,280,050...9,297,314 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 enables ISO (PMID:10220572), (PMID:18245269) UniProt PMID:10220572 PMID:18245269 RGD:42721988 NCBI chrNW_004955507:5,724,788...5,791,281
Ensembl chrNW_004955507:5,724,762...5,790,812 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 enables ISO (PMID:11581266), (PMID:19334674)
(PMID:18245269)		 UniProt PMID:11581266 PMID:18245269 PMID:19334674 NCBI chrNW_004955451:11,087,246...11,130,108
Ensembl chrNW_004955451:11,087,570...11,130,482 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 enables ISO (PMID:12695538), (PMID:15899835) UniProt PMID:12695538 PMID:15899835 NCBI chrNW_004955420:23,447,920...23,522,732
Ensembl chrNW_004955420:23,447,920...23,522,732 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 enables ISO PMID:10692506 UniProt PMID:10692506 RGD:1549867 NCBI chrNW_004955442:865,292...921,739
Ensembl chrNW_004955442:865,238...922,221 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (JR blood group) enables ISO (PMID:9861027) GO_Central PMID:9861027 NCBI chrNW_004955474:12,365,903...12,408,715 JBrowse link
ATPase-coupled lipid transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) enables ISO leukotriene LTC4 transport
(PMID:17050692)		 RGD
BHF-UCL		 PMID:12867490 PMID:17050692 RGD:2303048 NCBI chrNW_004955442:729,322...858,826
Ensembl chrNW_004955442:729,316...860,290 		JBrowse link
ATPase-coupled monoatomic cation transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 enables ISO (PMID:26181369) ARUK-UCL PMID:26181369 NCBI chrNW_004955414:32,216,243...32,289,028
Ensembl chrNW_004955414:32,216,196...32,289,053 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 enables ISO PMID:28842488 ARUK-UCL PMID:28842488 RGD:14995313 NCBI chrNW_004955413:17,385,966...17,510,220
Ensembl chrNW_004955413:17,382,564...17,510,132 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 enables ISO (PMID:19372756)
(PMID:20100892)		 RGD
ARUK-UCL		 PMID:12529322 PMID:19372756 PMID:20100892 RGD:1299865 NCBI chrNW_004955468:11,898,786...11,924,341
Ensembl chrNW_004955468:11,898,915...11,922,400 		JBrowse link
G Kcnj11 potassium inwardly rectifying channel subfamily J member 11 enables ISO PMID:28842488 ARUK-UCL PMID:28842488 RGD:14995313 NCBI chrNW_004955414:32,209,426...32,212,424
Ensembl chrNW_004955414:32,210,545...32,211,717 		JBrowse link
G Kcnj8 potassium inwardly rectifying channel subfamily J member 8 enables ISO PMID:28842488 ARUK-UCL PMID:28842488 RGD:14995313 NCBI chrNW_004955413:17,364,447...17,371,255
Ensembl chrNW_004955413:17,364,213...17,371,255 		JBrowse link
P-type calcium transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa5 annexin A5 ISO RGD PMID:9299392 RGD:10053703 NCBI chrNW_004955428:18,873,782...18,907,955
Ensembl chrNW_004955428:18,873,782...18,907,955 		JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 enables ISO PMID:9887021
PMID:9843705
(PMID:1329967), (PMID:8729696)		 RGD
MGI
ARUK-UCL
UniProt		 PMID:1329967 PMID:8729696 PMID:9843705 PMID:9887021 PMID:12222829 More... RGD:14995324 RGD:724593 RGD:727704 RGD:8554277 NCBI chrNW_004955493:6,559,995...6,578,461
Ensembl chrNW_004955493:6,559,995...6,578,461 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 enables ISO PMID:9851937
(PMID:29475982), (PMID:31819041)
(PMID:12756243), (PMID:9887021)
(PMID:16402920)		 RGD
BHF-UCL
MGI		 PMID:9851937 PMID:9887021 PMID:12409282 PMID:12756243 PMID:16402920 More... RGD:10047146 RGD:6904139 RGD:724593 NCBI chrNW_004955482:7,233,336...7,295,754
Ensembl chrNW_004955482:7,233,336...7,295,754 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 enables ISO (PMID:9843705) ARUK-UCL PMID:9843705 RGD:14995324 NCBI chrNW_004955467:12,911,679...12,941,322
Ensembl chrNW_004955467:12,911,679...12,941,924 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 enables ISO (PMID:7929331) RGD
UniProt		 PMID:2837461 PMID:7929331 RGD:631720 NCBI chrNW_004955561:1,727,935...1,851,907
Ensembl chrNW_004955561:1,727,935...1,851,907 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 enables ISO (PMID:8530416) RGD
BHF-UCL		 PMID:8530416 PMID:11779484 RGD:628395 NCBI chrNW_004955406:39,552,034...39,645,694
Ensembl chrNW_004955406:39,552,019...39,645,694 		JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 enables
NOT|enables		 ISO (PMID:12707275), (PMID:12810057), (PMID:16192278)
(PMID:16192278)
(PMID:10615129)		 RGD
UniProt		 PMID:10615129 PMID:12707275 PMID:12810057 PMID:15328051 PMID:16192278 More... RGD:1581800 RGD:7241224 NCBI chrNW_004955501:7,382,657...7,519,789
Ensembl chrNW_004955501:7,383,150...7,519,988 		JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 enables ISO (PMID:15677451), (PMID:15831496) UniProt PMID:15677451 PMID:15831496 NCBI chrNW_004955541:47,803...95,074
Ensembl chrNW_004955541:47,768...94,878 		JBrowse link
P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 enables ISO (PMID:28890335) UniProt PMID:28890335 NCBI chrNW_004955482:7,233,336...7,295,754
Ensembl chrNW_004955482:7,233,336...7,295,754 		JBrowse link
P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 enables ISO (PMID:7929331) SynGO PMID:7929331 NCBI chrNW_004955561:1,727,935...1,851,907
Ensembl chrNW_004955561:1,727,935...1,851,907 		JBrowse link
P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 enables ISO (PMID:18029012) SynGO PMID:18029012 NCBI chrNW_004955580:286,092...332,657
Ensembl chrNW_004955580:269,100...333,471 		JBrowse link
P-type divalent copper transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha enables ISO (PMID:15634671) MGI PMID:15634671 NCBI chrNW_004955557:1,355,471...1,515,725
Ensembl chrNW_004955557:1,355,397...1,515,393 		JBrowse link
G Atp7b ATPase copper transporting beta enables ISO (PMID:9837819)
(PMID:11237756), (PMID:15634671)		 UniProt
MGI		 PMID:9837819 PMID:11237756 PMID:15634671 NCBI chrNW_004955431:5,228,395...5,297,120
Ensembl chrNW_004955431:5,229,126...5,269,616 		JBrowse link
P-type magnesium transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem94 transmembrane protein 94 enables ISO (PMID:38513662) UniProt PMID:38513662 NCBI chrNW_004955553:2,305,425...2,353,596
Ensembl chrNW_004955553:2,329,995...2,352,898 		JBrowse link
P-type manganese transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 enables ISO (PMID:21187401) UniProt PMID:21187401 NCBI chrNW_004955501:7,382,657...7,519,789
Ensembl chrNW_004955501:7,383,150...7,519,988 		JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 enables ISO (PMID:15831496) UniProt PMID:15831496 NCBI chrNW_004955541:47,803...95,074
Ensembl chrNW_004955541:47,768...94,878 		JBrowse link
P-type monovalent copper transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha enables ISO (PMID:10419525) UniProt PMID:10419525 NCBI chrNW_004955557:1,355,471...1,515,725
Ensembl chrNW_004955557:1,355,397...1,515,393 		JBrowse link
P-type potassium transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 enables ISO (PMID:23229519) UniProt PMID:23229519 NCBI chrNW_004955435:19,537,224...19,563,631
Ensembl chrNW_004955435:19,536,634...19,564,580 		JBrowse link
P-type potassium:proton transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp12a ATPase H+/K+ transporting non-gastric alpha2 subunit contributes_to
enables		 ISO (PMID:8853415) RGD
UniProt		 PMID:8853415 PMID:16046397 RGD:2301240 NCBI chrNW_004955497:225,401...251,024
Ensembl chrNW_004955497:225,158...252,789 		JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha enables ISO (PMID:7762614) MGI PMID:7762614 NCBI chrNW_004955468:4,778,327...4,844,498
Ensembl chrNW_004955468:4,778,295...4,842,366 		JBrowse link
P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp12a ATPase H+/K+ transporting non-gastric alpha2 subunit enables ISO (PMID:9774385) UniProt PMID:9774385 NCBI chrNW_004955497:225,401...251,024
Ensembl chrNW_004955497:225,158...252,789 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 enables ISO (PMID:23229519)
(PMID:10360172), (PMID:15485817)
PMID:17939993
PMID:18075585
(PMID:18075585), (PMID:19542013)
(PMID:18052210)
(PMID:10636900), (PMID:19542013)		 RGD
MGI
UniProt
BHF-UCL
ARUK-UCL		 PMID:10360172 PMID:10636900 PMID:12531906 PMID:15485817 PMID:16624992 More... RGD:10047180 RGD:1581763 RGD:2302992 RGD:629542 RGD:8554378 NCBI chrNW_004955435:19,537,224...19,563,631
Ensembl chrNW_004955435:19,536,634...19,564,580 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 enables ISO (PMID:10636900)
(PMID:18052210)
(PMID:12539047), (PMID:23954377)
(PMID:18728015), (PMID:20100892)		 RGD
BHF-UCL
ARUK-UCL
UniProt		 PMID:10636900 PMID:12539047 PMID:16624992 PMID:18052210 PMID:18728015 More... RGD:2302992 NCBI chrNW_004955468:11,898,786...11,924,341
Ensembl chrNW_004955468:11,898,915...11,922,400 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 enables ISO (PMID:10636900)
(PMID:19666602), (PMID:21418141)
(PMID:15260953)		 BHF-UCL
MGI
UniProt		 PMID:10636900 PMID:15260953 PMID:19666602 PMID:21418141 NCBI chrNW_004955555:869,508...892,510
Ensembl chrNW_004955555:869,325...893,542 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 enables ISO (PMID:19542013) RGD
BHF-UCL		 PMID:16624992 PMID:19542013 RGD:2302992 NCBI chrNW_004955462:8,072,519...8,095,311
Ensembl chrNW_004955462:8,073,679...8,094,880 		JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 ISO RGD PMID:12562669 RGD:631758 NCBI chrNW_004955467:9,261,775...9,268,743
Ensembl chrNW_004955467:9,261,775...9,268,743 		JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 ISO RGD PMID:12562669 PMID:16624992 RGD:2302992 RGD:631758 NCBI chrNW_004955508:3,848,745...3,875,992
Ensembl chrNW_004955508:3,859,399...3,875,276 		JBrowse link
P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 enables ISO (MGI:4352602|PMID:19376779)
(PMID:19376779)		 BHF-UCL PMID:19376779 MGI:4352602 NCBI chrNW_004955555:869,508...892,510
Ensembl chrNW_004955555:869,325...893,542 		JBrowse link
P-type transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp13a3 ATPase 13A3 enables ISO (PMID:33310703) UniProt PMID:33310703 NCBI chrNW_004955420:14,295,844...14,375,325
Ensembl chrNW_004955420:14,295,768...14,375,325 		JBrowse link
protein-transporting ATPase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tomm20 translocase of outer mitochondrial membrane 20 enables ISO (PMID:14557246) HGNC-UCL PMID:14557246 NCBI chrNW_004955492:4,759,438...4,771,060
Ensembl chrNW_004955492:4,759,611...4,769,847 		JBrowse link
proton-transporting ATPase activity, rotational mechanism term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5f1b ATP synthase F1 subunit beta enables ISO (PMID:17510399) UniProt PMID:17510399 NCBI chrNW_004955458:4,188,167...4,195,575
Ensembl chrNW_004955458:4,186,461...4,195,494 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit d1 contributes_to ISO (PMID:12527205) MGI PMID:12527205 NCBI chrNW_004955484:9,167,439...9,206,193
Ensembl chrNW_004955484:9,167,439...9,206,193 		JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 enables ISO (PMID:17350184) UniProt PMID:17350184 NCBI chrNW_004955408:25,667,703...25,703,550
Ensembl chrNW_004955408:25,667,703...25,703,550 		JBrowse link
G Atp6v0e2 ATPase H+ transporting V0 subunit e2 enables ISO (PMID:17350184) UniProt PMID:17350184 NCBI chrNW_004955491:4,929,405...4,935,247
Ensembl chrNW_004955491:4,929,405...4,935,247 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A enables ISO (MGI:6695676|PMID:23863464)
(PMID:23863464)		 UniProt PMID:23863464 MGI:6695676 NCBI chrNW_004955427:13,868,683...13,922,028
Ensembl chrNW_004955427:13,868,171...13,922,028 		JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 enables ISO (PMID:12527205) MGI PMID:12527205 NCBI chrNW_004955417:27,340,916...27,376,541
Ensembl chrNW_004955417:27,356,483...27,375,747 		JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 enables ISO (PMID:12527205) MGI PMID:12527205 NCBI chrNW_004955487:5,711,235...5,735,081
Ensembl chrNW_004955487:5,711,235...5,735,081 		JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 enables ISO (PMID:11872743) MGI PMID:11872743 NCBI chrNW_004955454:5,669,883...5,688,623
Ensembl chrNW_004955454:5,666,921...5,688,645 		JBrowse link
G Atp6v1e2 ATPase H+ transporting V1 subunit E2 enables ISO (PMID:11872743) MGI PMID:11872743 NCBI chrNW_004955441:13,432,951...13,458,467
Ensembl chrNW_004955441:13,432,951...13,458,467 		JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 enables ISO (PMID:12527205) MGI PMID:12527205 NCBI chrNW_004955419:13,047,755...13,056,113
Ensembl chrNW_004955419:13,047,755...13,056,221 		JBrowse link
G Atp6v1g2 ATPase H+ transporting V1 subunit G2 enables ISO (PMID:12527205) MGI PMID:12527205 NCBI chrNW_004955437:86,053...88,355
Ensembl chrNW_004955437:86,053...88,355 		JBrowse link
G Atp6v1g3 ATPase H+ transporting V1 subunit G3 enables ISO (PMID:12527205) MGI PMID:12527205 NCBI chrNW_004955406:34,910,498...34,927,745
Ensembl chrNW_004955406:34,910,498...34,927,745 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14353
    ATP-dependent activity 319
      ATPase-coupled transmembrane transporter activity 64
        ABC-type transporter activity + 20
        ATPase-coupled 2-aminoethylphosphonate transporter activity 0
        ATPase-coupled arsenite transmembrane transporter activity 0
        ATPase-coupled inorganic anion transmembrane transporter activity + 0
        ATPase-coupled ion transmembrane transporter activity + 12
        ATPase-coupled lipid transmembrane transporter activity + 7
        ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity 0
        ATPase-coupled monoatomic cation transmembrane transporter activity + 36
        ATPase-coupled organic acid transmembrane transporter activity + 3
        ATPase-coupled urea transmembrane transporter activity 0
        P-type transmembrane transporter activity + 21
        protein-transporting ATPase activity + 1
Path 2
Term Annotations click to browse term
  molecular_function 14353
    transporter activity 875
      transmembrane transporter activity 796
        active transmembrane transporter activity 270
          primary active transmembrane transporter activity 80
            ATPase-coupled transmembrane transporter activity 64
              ABC-type transporter activity + 20
              ATPase-coupled 2-aminoethylphosphonate transporter activity 0
              ATPase-coupled arsenite transmembrane transporter activity 0
              ATPase-coupled inorganic anion transmembrane transporter activity + 0
              ATPase-coupled ion transmembrane transporter activity + 12
              ATPase-coupled lipid transmembrane transporter activity + 7
              ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity 0
              ATPase-coupled monoatomic cation transmembrane transporter activity + 36
              ATPase-coupled organic acid transmembrane transporter activity + 3
              ATPase-coupled urea transmembrane transporter activity 0
              P-type transmembrane transporter activity + 21
              protein-transporting ATPase activity + 1
paths to the root