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ONTOLOGY REPORT - ANNOTATIONS

Term:progesterone metabolic process
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Accession:GO:0042448 term browser browse the term
Definition:The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
Synonyms:exact_synonym: progesterone metabolism


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progesterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2388722 (PMID:12297623)		 Ensembl
RGD		 PMID:12297623 GO_REF:0000107 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 involved_in ISO
IBA		 (PMID:21232532)
GO_REF:0000033		 RGD
GO_Central		 PMID:21232532 GO_REF:0000033 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c14 aldo-keto reductase family 1, member C14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,156,286...66,173,277
Ensembl chr17:66,156,288...66,173,277 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 involved_in ISO (PMID:21232532) RGD PMID:21232532 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in
acts_upstream_of_or_within		 IDA
IBA
ISO		 GO_REF:0000033
PMID:8172618
(PMID:21232532)		 GO_Central
RGD		 PMID:21232532 PMID:4392955 PMID:8172618 GO_REF:0000033, RGD:2303525, RGD:1299435 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G AKR1C3l1 aldo-keto reductase family 1 member C3-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:22266943)		 UniProt
GO_Central
Ensembl
RGD		 PMID:22266943 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 IDA RGD PMID:19665544 RGD:4891164 NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,023,767...4,026,923 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in ISO (PMID:14640697) RGD PMID:14640697 NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in ISO (PMID:11294878) RGD PMID:11294878 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 IDA RGD PMID:4392955 RGD:2303525 NCBI chr 2:186,008,944...186,028,417
Ensembl chr 2:186,008,943...186,020,393 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:9202401 RGD:4892033 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:103036 (PMID:15471942)		 Ensembl
RGD		 PMID:15471942 GO_REF:0000107 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) RGD PMID:24530842 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:20133449 RGD:10059648 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IDA RGD PMID:1955079 RGD:1625116 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:1703300) RGD PMID:1703300 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 acts_upstream_of_or_within ISO MGI:3042568 (PMID:14963026) RGD PMID:14963026 NCBI chr10:83,357,329...83,379,873
Ensembl chr10:83,357,359...83,550,976 		JBrowse link
progesterone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 acts_upstream_of_or_within ISO MGI:3527218 (PMID:15471942) RGD PMID:15471942 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G Egr1 early growth response 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:8703054)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8703054 GO_REF:0000024 GO_REF:0000107 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:23045399 RGD:26884342 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir455 microRNA 455 IDA RGD PMID:23045399 RGD:26884342 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        ketone metabolic process 245
          progesterone metabolic process 22
            progesterone biosynthetic process + 9
            progesterone catabolic process 1
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        primary metabolic process 10582
          lipid metabolic process 1452
            steroid metabolic process 360
              C21-steroid hormone metabolic process 45
                progesterone metabolic process 22
                  progesterone biosynthetic process + 9
                  progesterone catabolic process 1
paths to the root