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ONTOLOGY REPORT - ANNOTATIONS

Term:dopamine catabolic process
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Accession:GO:0042420 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
Synonyms:exact_synonym: dopamine breakdown;   dopamine catabolism;   dopamine degradation
 xref: Reactome:R-HSA-379397 "Enzymatic degradation of dopamine by COMT";   Reactome:R-HSA-379398 "Enzymatic degradation of Dopamine by monoamine oxidase"


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dopamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO (PMID:9520487) RGD PMID:9520487 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within 		ISO
ISS
IEA
IBA 		(PMID:3443096), (PMID:7961964)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
MGI:1857556 (PMID:10051631)
(PMID:27148966), (PMID:7715704) 		RGD
UniProt
Ensembl
GO_Central		 PMID:3443096 PMID:7715704 PMID:7961964 PMID:10051631 PMID:27148966 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Maoa monoamine oxidase A acts_upstream_of_or_within ISO (PMID:9520487) RGD PMID:9520487 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Pde1b phosphodiesterase 1B acts_upstream_of_positive_effect ISO
IEA 		MGI:3604470 (PMID:17559891)
GO_REF:0000107 		RGD
Ensembl		 PMID:17559891 GO_REF:0000107 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO
IEA 		MGI:2386303 (PMID:9520487)
GO_REF:0000107 		RGD
Ensembl		 PMID:9520487 GO_REF:0000107 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:8093002) 		UniProt
RGD		 PMID:8093002 GO_REF:0000024 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        amine metabolic process 127
          biogenic amine metabolic process 115
            catecholamine metabolic process 68
              dopamine metabolic process 52
                dopamine catabolic process 8
paths to the root