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ONTOLOGY REPORT - ANNOTATIONS

Term:dopamine biosynthetic process
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Accession:GO:0042416 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
Synonyms:exact_synonym: dopamine anabolism;   dopamine biosynthesis;   dopamine formation;   dopamine synthesis

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dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:20097214 RGD:6903884 NCBI chrNW_004624730:25,964,848...26,006,468
Ensembl chrNW_004624730:25,964,811...26,006,463 		JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO RGD PMID:20097214 RGD:6903884 NCBI chrNW_004624967:327,627...332,000
Ensembl chrNW_004624967:329,284...330,372 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ISO RGD PMID:12438507 RGD:704388 NCBI chrNW_004624768:908,907...1,024,953
Ensembl chrNW_004624768:909,099...1,024,902 		JBrowse link
G Dao D-amino acid oxidase involved_in ISO (PMID:17303072)
(PMID:17042912) 		UniProt PMID:17042912 PMID:17303072 NCBI chrNW_004624747:12,094,658...12,117,000
Ensembl chrNW_004624747:12,105,133...12,116,604 		JBrowse link
G Ddc dopa decarboxylase involved_in ISO
IEA 		RGD
Ensembl		 PMID:12703659 GO_REF:0000107 RGD:4139893 NCBI chrNW_004624740:3,674,727...3,732,058
Ensembl chrNW_004624740:3,674,609...3,732,676 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:16338639) UniProt PMID:16338639 NCBI chrNW_004624731:14,459,164...14,502,485
Ensembl chrNW_004624731:14,459,303...14,500,429 		JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624783:11,291,601...11,319,467
Ensembl chrNW_004624783:11,291,497...11,320,952 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4 group A member 2 acts_upstream_of_or_within ISO (PMID:16782508), (PMID:9608532) MGI PMID:9608532 PMID:16782508 NCBI chrNW_004624732:9,572,160...9,589,624
Ensembl chrNW_004624732:9,581,779...9,589,942 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO (PMID:9520487) MGI PMID:9520487 NCBI chrNW_004624751:694,165...720,287
Ensembl chrNW_004624751:694,099...719,465 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO (PMID:10707987) MGI PMID:10707987 NCBI chrNW_004624757:17,393,046...17,528,783
Ensembl chrNW_004624757:17,392,998...17,528,320 		JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624835:2,363,059...2,436,536
Ensembl chrNW_004624835:2,363,139...2,437,643 		JBrowse link
G Th tyrosine hydroxylase involved_in IEA UniProt GO_REF:0000041 NCBI chrNW_004624767:15,003,073...15,010,207
Ensembl chrNW_004624767:15,003,092...15,010,154 		JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:9520487)
(PMID:7592982), (PMID:7715703) 		MGI
RGD
TreeGrafter		 PMID:2427363 PMID:7592982 PMID:7715703 PMID:9520487 PMID:19584816 More... GO_REF:0000118 RGD:1580046 RGD:4139888 RGD:5130972 NCBI chrNW_004624767:15,003,073...15,010,207
Ensembl chrNW_004624767:15,003,092...15,010,154 		JBrowse link
negative regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nt5dc2 5'-nucleotidase domain containing 2 involved_in ISO PMID:31279527 UniProt PMID:31279527 RGD:408345212 NCBI chrNW_004624822:4,675,430...4,684,074
Ensembl chrNW_004624822:4,675,430...4,685,553 		JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chrNW_004624738:27,747,770...27,831,213
Ensembl chrNW_004624738:27,747,696...27,834,054 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:19703902) ParkinsonsUK-UCL PMID:19703902 NCBI chrNW_004624818:3,900,917...3,915,457
Ensembl chrNW_004624818:3,900,917...3,911,042 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:26203154) ParkinsonsUK-UCL PMID:26203154 NCBI chrNW_004624914:160,483...188,534
Ensembl chrNW_004624914:160,483...188,490 		JBrowse link
regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member involved_in ISO (PMID:26711020) UniProt PMID:26711020 NCBI chrNW_004624747:20,407,190...20,438,605
Ensembl chrNW_004624747:20,403,717...20,438,690 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17646
    cellular process 17217
      metabolic process 10993
        amine metabolic process 123
          biogenic amine metabolic process 112
            catecholamine metabolic process 66
              dopamine metabolic process 52
                dopamine biosynthetic process 17
                  dopamine biosynthetic process from tyrosine 1
                  negative regulation of dopamine biosynthetic process 1
                  positive regulation of dopamine biosynthetic process 3
                  regulation of dopamine biosynthetic process + 5
paths to the root