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ONTOLOGY REPORT - ANNOTATIONS

Term:dopamine biosynthetic process
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Accession:GO:0042416 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
Synonyms:exact_synonym: dopamine anabolism;   dopamine biosynthesis;   dopamine formation;   dopamine synthesis


show annotations for term's descendants           Sort by:
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a involved_in ISO
IEA 		RGD
GO_Central
Ensembl		 PMID:20097214 GO_REF:0000096 GO_REF:0000107 RGD:6903884 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in ISO
IEA 		RGD
Ensembl
GO_Central		 PMID:20097214 GO_REF:0000096 GO_REF:0000107 RGD:6903884 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 ISO RGD PMID:12438507 RGD:704388 NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 involved_in ISO RGD
GO_Central		 PMID:19818757 GO_REF:0000096 RGD:5143981 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Dao D-amino acid oxidase involved_in IMP
ISO 		(PMID:17042912) UniProt
GO_Central		 PMID:17042912 GO_REF:0000119 NCBI chr 5:114,137,696...114,163,736
Ensembl chr 5:114,141,764...114,163,743 		JBrowse link
G Ddc dopa decarboxylase involved_in ISO
IEA 		RGD
GO_Central
UniProt		 PMID:12703659 GO_REF:0000041 GO_REF:0000096 RGD:4139893 NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr14:47,391,352...47,426,870
Ensembl chr14:47,391,352...47,426,870 		JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within IMP (PMID:15218106) MGI PMID:15218106 NCBI chr 6:25,668,522...25,689,979
Ensembl chr 6:25,665,877...25,690,728 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 acts_upstream_of_or_within IMP (PMID:16782508), (PMID:9608532) MGI PMID:9608532 PMID:16782508 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015 		JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 acts_upstream_of_or_within IMP (PMID:9520487) MGI PMID:9520487 NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791 		JBrowse link
G Snca synuclein, alpha acts_upstream_of_or_within IMP (PMID:10707987) MGI PMID:10707987 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in IMP (PMID:16257223) UniProt PMID:16257223 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Th tyrosine hydroxylase involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865 		JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase acts_upstream_of_or_within
involved_in 		IDA
ISO
IBA
IMP
TAS 		(PMID:9520487)
(PMID:7592982), (PMID:7715703)
(PMID:10212311) 		MGI
RGD
GO_Central		 PMID:2427363 PMID:7592982 PMID:7715703 PMID:9520487 PMID:10212311 More... GO_REF:0000033 GO_REF:0000096 RGD:1580046 RGD:4139888 RGD:5130972 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865 		JBrowse link
negative regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nt5dc2 5'-nucleotidase domain containing 2 involved_in ISO PMID:31279527 UniProt PMID:31279527 RGD:408345212 NCBI chr14:30,853,046...30,861,081
Ensembl chr14:30,853,010...30,861,081 		JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 involved_in ISO RGD
GO_Central		 PMID:19457096 GO_REF:0000096 RGD:5128877 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838 		JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in IMP (PMID:26203154) ParkinsonsUK-UCL PMID:26203154 NCBI chr 8:85,987,014...86,026,146
Ensembl chr 8:85,987,021...86,026,431 		JBrowse link
regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2, mitochondrial involved_in IMP (PMID:26711020) UniProt PMID:26711020 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28626
    cellular process 18393
      metabolic process 11623
        amine metabolic process 130
          biogenic amine metabolic process 119
            catecholamine metabolic process 69
              dopamine metabolic process 52
                dopamine biosynthetic process 18
                  dopamine biosynthetic process from tyrosine 1
                  negative regulation of dopamine biosynthetic process 1
                  positive regulation of dopamine biosynthetic process 3
                  regulation of dopamine biosynthetic process + 5
paths to the root