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ONTOLOGY REPORT - ANNOTATIONS

Term:dopamine biosynthetic process
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Accession:GO:0042416 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
Synonyms:exact_synonym: dopamine anabolism;   dopamine biosynthesis;   dopamine formation;   dopamine synthesis

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dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:20097214 RGD:6903884 NCBI chrNW_004955474:8,733,942...8,781,305
Ensembl chrNW_004955474:8,733,942...8,781,255 		JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO RGD PMID:20097214 RGD:6903884 NCBI chrNW_004955534:3,653,112...3,654,248
Ensembl chrNW_004955534:3,653,157...3,654,248 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ISO RGD PMID:12438507 RGD:704388 NCBI chrNW_004955416:30,687,518...30,798,700
Ensembl chrNW_004955416:30,687,478...30,798,700 		JBrowse link
G Dao D-amino acid oxidase involved_in ISO (PMID:17303072)
(PMID:17042912) 		UniProt PMID:17042912 PMID:17303072 NCBI chrNW_004955455:10,095,597...10,127,244
Ensembl chrNW_004955455:10,095,300...10,127,666 		JBrowse link
G Ddc dopa decarboxylase involved_in ISO (PMID:19703902) RGD
ParkinsonsUK-UCL		 PMID:12703659 PMID:19703902 RGD:4139893 NCBI chrNW_004955456:3,513,779...3,582,851
Ensembl chrNW_004955456:3,513,042...3,582,911 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:16338639) UniProt PMID:16338639 NCBI chrNW_004955409:8,624,225...8,670,436
Ensembl chrNW_004955409:8,624,468...8,668,614 		JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within ISO (PMID:15218106) MGI PMID:15218106 NCBI chrNW_004955479:6,061,424...6,080,129
Ensembl chrNW_004955479:6,057,276...6,080,994 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4 group A member 2 acts_upstream_of_or_within ISO (PMID:16782508), (PMID:9608532) MGI PMID:9608532 PMID:16782508 NCBI chrNW_004955449:16,928,780...16,944,536
Ensembl chrNW_004955449:16,937,794...16,945,731 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO (PMID:9520487) MGI PMID:9520487 NCBI chrNW_004955504:721,470...747,553
Ensembl chrNW_004955504:721,429...747,630 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO (PMID:10707987) MGI PMID:10707987 NCBI chrNW_004955405:854,011...962,741
Ensembl chrNW_004955405:853,946...965,403 		JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in ISO (PMID:16257223) UniProt PMID:16257223 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248 		JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228), (PMID:19703902) ParkinsonsUK-UCL PMID:12457228 PMID:19703902 NCBI chrNW_004955422:13,943,590...13,951,102
Ensembl chrNW_004955422:13,943,552...13,951,137 		JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase involved_in
acts_upstream_of_or_within 		ISO PMID:11943812
(PMID:9520487)
(PMID:7592982), (PMID:7715703) 		BHF-UCL
RGD
MGI		 PMID:2427363 PMID:7592982 PMID:7715703 PMID:9520487 PMID:11943812 More... RGD:1580046 RGD:4139888 RGD:5129111 RGD:5130972 NCBI chrNW_004955422:13,943,590...13,951,102
Ensembl chrNW_004955422:13,943,552...13,951,137 		JBrowse link
negative regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nt5dc2 5'-nucleotidase domain containing 2 involved_in ISO PMID:31279527 UniProt PMID:31279527 RGD:408345212 NCBI chrNW_004955430:2,517,943...2,526,423
Ensembl chrNW_004955430:2,517,943...2,526,423 		JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chrNW_004955441:13,244,626...13,328,220
Ensembl chrNW_004955441:13,244,626...13,328,369 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:19703902) ParkinsonsUK-UCL PMID:19703902 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:26203154) ParkinsonsUK-UCL PMID:26203154 NCBI chrNW_004955448:207,582...240,264
Ensembl chrNW_004955448:204,991...240,160 		JBrowse link
regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member involved_in ISO (PMID:26711020) UniProt PMID:26711020 NCBI chrNW_004955482:8,352,569...8,383,097
Ensembl chrNW_004955482:8,352,569...8,384,899 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12627
    cellular process 12058
      metabolic process 7972
        amine metabolic process 101
          biogenic amine metabolic process 93
            catecholamine metabolic process 59
              dopamine metabolic process 47
                dopamine biosynthetic process 17
                  dopamine biosynthetic process from tyrosine 1
                  negative regulation of dopamine biosynthetic process 1
                  positive regulation of dopamine biosynthetic process 3
                  regulation of dopamine biosynthetic process + 5
paths to the root