Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:thyroid hormone metabolic process
go back to main search page
Accession:GO:0042403 term browser browse the term
Definition:The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
Synonyms:exact_synonym: thyroid hormone metabolism


show annotations for term's descendants           Sort by:
thyroid hormone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crym crystallin, mu involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:3703787 (PMID:17264173)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:17264173 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633 		JBrowse link
G Dio1 iodothyronine deiodinase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dio2 iodothyronine deiodinase 2 involved_in TAS
IBA
ISO
IDA		 GO_REF:0000033
(PMID:19651899)		 GO_Central
RGD		 PMID:19651899 PMID:11934678 PMID:15550511 GO_REF:0000033, RGD:628323, RGD:1626436 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dio3 iodothyronine deiodinase 3 involved_in TAS
IBA
ISO		 GO_REF:0000033
UniProtKB:P36021 (PMID:26305885)		 GO_Central
RGD		 PMID:26305885 PMID:7622463 GO_REF:0000033, RGD:68236 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Duox2 dual oxidase 2 acts_upstream_of_or_within ISO MGI:3712359 (PMID:17440044) RGD PMID:17440044 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Gcnt4 glucosaminyl (N-acetyl) transferase 4 acts_upstream_of_or_within ISO MGI:3849682 (PMID:19349303) RGD PMID:19349303 NCBI chr 2:28,253,325...28,283,082
Ensembl chr 2:28,252,860...28,283,082 		JBrowse link
G Iyd iodotyrosine deiodinase involved_in ISO
IBA
ISS		 (PMID:25395621)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:25395621 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 acts_upstream_of_or_within ISO MGI:1856525 RGD MGI:85368 NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758 		JBrowse link
G Reln reelin acts_upstream_of_or_within ISO MGI:1856398 RGD MGI:85368 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 acts_upstream_of ISO UniProtKB:P55073 (PMID:26305885) RGD PMID:26305885 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771 		JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 IDA RGD PMID:11316767 RGD:727314 NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 involved_in ISO
IDA		 (PMID:11368519)
(PMID:9644246)
PMID:8530477
(PMID:9443824), (PMID:9463486)		 RGD PMID:9443824 PMID:9463486 PMID:9644246 PMID:11368519 PMID:8530477 RGD:1299515 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 involved_in ISO (PMID:10199779) RGD PMID:10199779 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tg thyroglobulin acts_upstream_of_or_within ISO MGI:1856829 (PMID:3803305) RGD PMID:3803305 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Ttr transthyretin TAS RGD PMID:11995998 RGD:737655 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
positive regulation of thyroid hormone generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (PMID:19248180), (PMID:19723756) RGD PMID:19248180 PMID:19723756 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Hpn hepsin involved_in ISS
ISO		 GO_REF:0000024
(PMID:17620368)		 UniProt
RGD		 PMID:17620368 GO_REF:0000024 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Pax8 paired box 8 involved_in ISO
ISS		 (PMID:15356023)
(PMID:12586753)
GO_REF:0000024		 RGD
UniProt		 PMID:12586753 PMID:15356023 GO_REF:0000024 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 involved_in ISO
IEA		 (PMID:18566113)
GO_REF:0000107		 RGD
Ensembl		 PMID:18566113 GO_REF:0000107 NCBI chr 4:174,466,621...174,513,290
Ensembl chr 4:174,466,631...174,513,289 		JBrowse link
regulation of thyroid hormone generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duoxa1 dual oxidase maturation factor 1 acts_upstream_of_or_within ISO MGI:1914061 (PMID:22301785) RGD PMID:22301785 NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499 		JBrowse link
G Duoxa2 dual oxidase maturation factor 2 acts_upstream_of_or_within ISO MGI:2384861 (PMID:22301785) RGD PMID:22301785 NCBI chr 3:109,245,337...109,249,055
Ensembl chr 3:109,245,476...109,248,968 		JBrowse link
thyroid hormone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio2 iodothyronine deiodinase 2 acts_upstream_of_or_within ISO MGI:2182450 (PMID:11731615) RGD PMID:11731615 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dio3 iodothyronine deiodinase 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:20203194)
MGI:2664293 (PMID:16410833), (PMID:20203194), (PMID:25002520)		 RGD PMID:16410833 PMID:20203194 PMID:25002520 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
thyroid hormone generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cga glycoprotein hormones, alpha polypeptide involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1857152 (PMID:12114718)		 GO_Central
RGD		 PMID:12114718 GO_REF:0000033 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191 		JBrowse link
G Cpq carboxypeptidase Q involved_in IDA
IBA		 PMID:22127294
GO_REF:0000033		 GO_Central PMID:22127294 GO_REF:0000033, RGD:8554022 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546 		JBrowse link
G Ctsb cathepsin B involved_in IEA
ISO		 GO_REF:0000107
(PMID:12782676)		 Ensembl
RGD		 PMID:12782676 GO_REF:0000107 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsk cathepsin K involved_in ISO
ISS		 (PMID:11082042)
(PMID:12782676)
GO_REF:0000024		 RGD
UniProt		 PMID:11082042 PMID:12782676 GO_REF:0000024 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Ctsl cathepsin L involved_in ISO (PMID:12782676) RGD PMID:12782676 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Dio2 iodothyronine deiodinase 2 IDA RGD PMID:15550511 RGD:1626436 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Duox1 dual oxidase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duox2 dual oxidase 2 involved_in TAS
IEA		 GO_REF:0000041 UniProt
RGD		 PMID:12538618 GO_REF:0000041, RGD:632568 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Foxe1 forkhead box E1 acts_upstream_of_or_within ISO MGI:2181780 (PMID:9697704) RGD PMID:9697704 NCBI chr 5:60,630,027...60,632,835
Ensembl chr 5:60,630,027...60,632,835 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:1861125 (PMID:10882104) RGD PMID:10882104 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Slc16a10 solute carrier family 16 member 10 acts_upstream_of_or_within_negative_effect ISO MGI:1203732 (PMID:24248460) RGD PMID:24248460 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 acts_upstream_of_or_within_negative_effect ISO MGI:1919722|MGI:3710233 (PMID:24248460) RGD PMID:24248460 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771 		JBrowse link
G Slc26a7 solute carrier family 26 member 7 involved_in ISO (PMID:30333321) RGD PMID:30333321 NCBI chr 5:27,884,400...28,021,865
Ensembl chr 5:27,887,042...28,021,658 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 involved_in TAS
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:8559252 GO_REF:0000002, RGD:68854 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Tg thyroglobulin involved_in TAS
ISO
IBA
IEA
IDA		 (PMID:12782676)
GO_REF:0000033
GO_REF:0000107
(PMID:11082042), (PMID:12387814)
(PMID:32025030)		 RGD
GO_Central
Ensembl		 PMID:11082042 PMID:12387814 PMID:12782676 PMID:32025030 PMID:11884402 More... GO_REF:0000033 GO_REF:0000107, RGD:728752, RGD:1600150 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tpo thyroid peroxidase involved_in TAS
ISO
IEA		 (PMID:12387814)
GO_REF:0000041		 RGD
UniProt		 PMID:12387814 PMID:15917231 GO_REF:0000041, RGD:1599649 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        hormone metabolic process 261
          thyroid hormone metabolic process 35
            thyroid hormone catabolic process 2
            thyroid hormone generation + 23
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        organic hydroxy compound metabolic process 585
          phenol-containing compound metabolic process 137
            thyroid hormone metabolic process 35
              thyroid hormone catabolic process 2
              thyroid hormone generation + 23
paths to the root