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ONTOLOGY REPORT - ANNOTATIONS

Term:xenobiotic catabolic process
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Accession:GO:0042178 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organism exposed to it, carried out by individual cells. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms:exact_synonym: xenobiotic breakdown;   xenobiotic catabolism;   xenobiotic degradation
 related_synonym: drug breakdown;   drug catabolic process;   drug catabolism;   drug degradation;   exogenous drug breakdown;   exogenous drug catabolic process;   exogenous drug catabolism;   exogenous drug degradation
 alt_id: GO:0042737;   GO:0042738


show annotations for term's descendants           Sort by:
xenobiotic catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 IMP RGD PMID:18088505 RGD:14700808 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 IDA RGD PMID:10725307 RGD:2312871 NCBI chr16:52,487,870...52,554,110
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Cryz crystallin zeta involved_in ISO
ISS		 (PMID:17497241)
GO_REF:0000024		 RGD
UniProt		 PMID:17497241 GO_REF:0000024 NCBI chr 2:246,211,707...246,239,472
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO
IEA		 (PMID:18356043), (PMID:18619574)
GO_REF:0000107		 RGD
Ensembl		 PMID:18356043 PMID:18619574 GO_REF:0000107 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 involved_in ISO (PMID:19029318) RGD PMID:19029318 NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 involved_in ISO
IDA		 (PMID:19029318) RGD PMID:19029318 PMID:16039681 RGD:401965478 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:18619574) RGD PMID:18619574
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 involved_in
NOT|involved_in		 ISO (PMID:15051713)
(PMID:18838503)		 RGD PMID:15051713 PMID:18838503 NCBI chr 7:115,789,026...115,793,430
Ensembl chr 7:113,908,947...113,922,084 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in ISO (PMID:15039299) RGD PMID:15039299 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:15039299), (PMID:15327587), (PMID:18356043), (PMID:18619574) RGD PMID:15039299 PMID:15327587 PMID:18356043 PMID:18619574 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 involved_in ISO (PMID:15039299) RGD PMID:15039299 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO
IEA		 MGI:5487815 (PMID:19262426)
GO_REF:0000107		 RGD
Ensembl		 PMID:19262426 GO_REF:0000107 NCBI chr13:77,687,909...77,706,100
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 involved_in IDA
ISO		 PMID:17112229
(PMID:8373352)		 RGD PMID:8373352 PMID:17112229 RGD:12793043 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in IDA
ISO		 PMID:17112229
(PMID:16549767), (PMID:2034681), (PMID:8373352)		 RGD PMID:2034681 PMID:8373352 PMID:16549767 PMID:17112229 RGD:12793043 NCBI chr 2:198,312,179...198,316,962
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:8373352)
(PMID:12069689)
GO_REF:0000107		 RGD
Ensembl		 PMID:8373352 PMID:12069689 GO_REF:0000107 NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 involved_in ISO
IEA		 (PMID:8373352)
GO_REF:0000107		 RGD
Ensembl		 PMID:8373352 GO_REF:0000107 NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:198,254,872...198,260,365
Ensembl chr 2:195,566,701...195,572,203 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:12928150)		 UniProt
Ensembl
RGD		 PMID:12928150 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Nos1 nitric oxide synthase 1 acts_upstream_of_or_within ISO
IEA		 MGI:1857227 (PMID:11158245)
GO_REF:0000107		 RGD
Ensembl		 PMID:11158245 GO_REF:0000107 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 involved_in ISO
IEA
ISS		 (PMID:12578355)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12578355 GO_REF:0000024 GO_REF:0000107 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nudt15 nudix hydrolase 15 involved_in ISO (PMID:26878724) RGD PMID:26878724 NCBI chr15:55,117,312...55,123,983
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
G Prkce protein kinase C, epsilon involved_in ISO
IEA		 (PMID:18556656)
GO_REF:0000107		 RGD
Ensembl		 PMID:18556656 GO_REF:0000107 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
biphenyl catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
dibenzo-p-dioxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA
IMP		 2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:15812643 PMID:12914780 RGD:2306662, RGD:2306673 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:119,079,775...119,088,624 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:127,750,771...127,759,589
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Pon3 paraoxonase 3 IDA RGD PMID:12946270 RGD:1303961 NCBI chr 4:34,323,546...34,350,244
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        catabolic process 2956
          xenobiotic catabolic process 31
            2-aminobenzenesulfonate catabolic process 0
            2-nitropropane catabolic process 0
            3-hydroxyphenylacetate catabolic process 0
            3-methylquinoline catabolic process 0
            3-phenylpropionate catabolic process 0
            4-nitrophenol catabolic process 0
            6-hydroxycineole catabolic process 0
            acrylonitrile catabolic process 0
            adamantanone catabolic process 0
            anaerobic acetylene catabolic process 0
            anaerobic cyclohexane-1-carboxylate catabolic process 0
            anthranilate catabolic process 0
            arsonoacetate catabolic process 0
            biphenyl catabolic process 2
            bisphenol A catabolic process 0
            caprolactam catabolic process 0
            carbazole catabolic process 0
            cresol catabolic process + 0
            dibenzo-p-dioxin catabolic process 1
            dibenzofuran catabolic process 0
            dibenzothiophene catabolic process 0
            exogenous antibiotic catabolic process 0
            fluorene catabolic process 0
            halogenated hydrocarbon catabolic process + 0
            insecticide catabolic process + 0
            methyl ethyl ketone catabolic process 0
            methylnaphthalene catabolic process 0
            nylon catabolic process 0
            organosilicon catabolic process + 0
            phenanthrene catabolic process + 0
            phenylacetate catabolic process 3
            phenylmercury acetate catabolic process 0
            phthalate catabolic process 0
            propylene catabolic process 0
            s-triazine compound catabolic process + 0
            styrene catabolic process 0
            thiocyanate catabolic process 0
            toluene catabolic process + 0
            xylene catabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to chemical 5958
        cellular response to chemical stimulus 2743
          cellular response to xenobiotic stimulus 233
            xenobiotic metabolic process 125
              xenobiotic catabolic process 31
                2-aminobenzenesulfonate catabolic process 0
                2-nitropropane catabolic process 0
                3-hydroxyphenylacetate catabolic process 0
                3-methylquinoline catabolic process 0
                3-phenylpropionate catabolic process 0
                4-nitrophenol catabolic process 0
                6-hydroxycineole catabolic process 0
                acrylonitrile catabolic process 0
                adamantanone catabolic process 0
                anaerobic acetylene catabolic process 0
                anaerobic cyclohexane-1-carboxylate catabolic process 0
                anthranilate catabolic process 0
                arsonoacetate catabolic process 0
                biphenyl catabolic process 2
                bisphenol A catabolic process 0
                caprolactam catabolic process 0
                carbazole catabolic process 0
                cresol catabolic process + 0
                dibenzo-p-dioxin catabolic process 1
                dibenzofuran catabolic process 0
                dibenzothiophene catabolic process 0
                exogenous antibiotic catabolic process 0
                fluorene catabolic process 0
                halogenated hydrocarbon catabolic process + 0
                insecticide catabolic process + 0
                methyl ethyl ketone catabolic process 0
                methylnaphthalene catabolic process 0
                nylon catabolic process 0
                organosilicon catabolic process + 0
                phenanthrene catabolic process + 0
                phenylacetate catabolic process 3
                phenylmercury acetate catabolic process 0
                phthalate catabolic process 0
                propylene catabolic process 0
                s-triazine compound catabolic process + 0
                styrene catabolic process 0
                thiocyanate catabolic process 0
                toluene catabolic process + 0
                xylene catabolic process + 0
paths to the root