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ONTOLOGY REPORT - ANNOTATIONS
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Term:
Fc-gamma receptor signaling pathway involved in phagocytosis
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Accession:
GO:0038096
browse the term
Definition:
An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
Synonyms:
exact_synonym:
Fc gamma receptor-dependent phagocytosis; Fc-gamma receptor signalling pathway involved in phagocytosis; Fcgamma receptor-mediated phagocytosis; IgG-mediated phagocytosis
xref:
Reactome:R-HSA-2029480 "Fcgamma receptor (FCGR) dependent phagocytosis"; Reactome:R-HSA-9664422 "FCGR3A-mediated phagocytosis"
show annotations for term's descendants Sort by:
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evidence
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Rat (6)
Mouse (6)
Human (25)
Chinchilla (6)
Bonobo (6)
Dog (6)
Squirrel (6)
Pig (6)
Green Monkey (6)
Naked Mole-rat (6)
All
Genes (6)
Fc-gamma receptor signaling pathway involved in phagocytosis
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Fcer2
Fc epsilon receptor II
involved_in
ISO
(PMID:7544003)
RGD
PMID:7544003
NCBI chr12:6,540,697...6,552,364
Ensembl chr12:1,742,815...1,754,476
G
Ifng
interferon gamma
involved_in
ISO
(PMID:7544003)
RGD
PMID:7544003
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
G
Myo1g
myosin IG
involved_in
ISO
IEA
(PMID:23038771)
GO_REF:0000107
RGD
Ensembl
PMID:23038771
GO_REF:0000107
NCBI chr14:85,600,619...85,615,760
Ensembl chr14:81,386,701...81,401,843
G
Nos2
nitric oxide synthase 2
involved_in
ISO
(PMID:7544003)
RGD
PMID:7544003
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Appl1
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
involved_in
ISO
(PMID:25568335)
RGD
PMID:25568335
NCBI chr16:2,125,234...2,173,457
Ensembl chr16:2,121,255...2,166,692
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Appl2
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
involved_in
ISO
IEA
(PMID:25568335)
GO_REF:0000107
RGD
Ensembl
PMID:25568335
GO_REF:0000107
NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:20,135,375...20,184,754
Term paths to the root
one shortest
all shortest
one longest
all longest
one shortest and longest
all
Path 1
Term
Annotations
biological_process
20567
immune system process
3132
immune effector process
847
immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
6
Fc-gamma receptor signaling pathway involved in phagocytosis
6
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
1
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
1
regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
+
2
Path 2
Term
Annotations
biological_process
20567
biological regulation
13841
regulation of biological process
13403
regulation of immune system process
1746
positive regulation of immune system process
1208
positive regulation of immune response
834
activation of immune response
599
immune response-activating signaling pathway
516
immune response-activating cell surface receptor signaling pathway
310
Fc receptor mediated stimulatory signaling pathway
20
Fc-gamma receptor signaling pathway involved in phagocytosis
6
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
1
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
1
regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
+
2