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ONTOLOGY REPORT - ANNOTATIONS

Term:Fc receptor signaling pathway
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Accession:GO:0038093 term browser browse the term
Definition:The series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
Synonyms:exact_synonym: Fc receptor signalling pathway
 never_in_taxon: NCBITaxon:4751 ! Fungi


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Fc receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcar Fc alpha receptor involved_in ISO (PMID:25339672) RGD PMID:25339672 NCBI chr 1:69,626,458...69,660,558 JBrowse link
G Fcmr Fc mu receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:44,889,628...44,903,926
Ensembl chr13:42,337,414...42,351,653 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO
IEA		 (PMID:20100931)
GO_REF:0000104
GO_REF:0000107
GO_REF:0000002		 RGD
UniProt
Ensembl
InterPro		 PMID:20100931 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Pigr polymeric immunoglobulin receptor involved_in ISO
IEA		 (PMID:22022593)
GO_REF:0000107		 RGD
Ensembl		 PMID:22022593 GO_REF:0000107 NCBI chr13:44,851,001...44,879,143
Ensembl chr13:42,298,914...42,326,875 		JBrowse link
Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc epsilon receptor Ia involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:88,218,427...88,224,723
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fcer1g Fc epsilon receptor Ig involved_in ISO
IEA		 (PMID:16735691)
GO_REF:0000108		 RGD
GOC		 PMID:16735691 GO_REF:0000108 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fcer2 Fc epsilon receptor II involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:6,540,697...6,552,364
Ensembl chr12:1,742,815...1,754,476 		JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:85,782,636...85,792,656
Ensembl chr13:83,249,872...83,259,921 		JBrowse link
G Fer FER tyrosine kinase involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:12192036)
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:12192036 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:110,967,317...111,274,315
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
Fc-gamma receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd247 Cd247 molecule involved_in ISO
IEA		 (PMID:8478617)
GO_REF:0000107		 RGD
Ensembl		 PMID:8478617 GO_REF:0000107 NCBI chr13:80,576,264...80,651,422
Ensembl chr13:78,043,307...78,122,263 		JBrowse link
G Cd33 CD33 molecule involved_in ISO (PMID:10556798) RGD PMID:10556798 NCBI chr 1:103,071,985...103,086,687
Ensembl chr 1:93,930,971...93,950,149 		JBrowse link
G Clec4d C-type lectin domain family 4, member D acts_upstream_of_or_within ISO (PMID:23602766) RGD PMID:23602766 NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848 		JBrowse link
G Clec4e C-type lectin domain family 4, member E acts_upstream_of_or_within ISO
IEA		 (PMID:23602766)
GO_REF:0000107		 RGD
Ensembl		 PMID:23602766 GO_REF:0000107 NCBI chr 4:158,292,624...158,298,607
Ensembl chr 4:156,607,614...156,612,767 		JBrowse link
G Fcer1g Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:23602766)		 GO_Central
RGD		 PMID:23602766 GO_REF:0000033 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fcgr1a Fc gamma receptor 1A involved_in ISO (PMID:10556798) RGD PMID:10556798 NCBI chr 2:186,539,941...186,548,941
Ensembl chr 2:183,851,077...183,859,994 		JBrowse link
G Fcgr2a Fc gamma receptor 2A involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:85,813,516...85,830,269
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Fcgr2al1 Fc gamma receptor 2A like 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:83,302,874...83,315,744
Ensembl chr13:83,280,790...83,484,920 		JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in ISO (PMID:2142460) RGD PMID:2142460 NCBI chr13:85,725,897...85,740,517
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO
IEA		 (PMID:23024279), (PMID:8478617)
GO_REF:0000108		 RGD
GOC		 PMID:8478617 PMID:23024279 GO_REF:0000108 NCBI chr13:85,782,636...85,792,656
Ensembl chr13:83,249,872...83,259,921 		JBrowse link
G Fcgrt Fc gamma receptor and transporter involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:104,710,902...104,720,685
Ensembl chr 1:95,567,175...95,584,084 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:8478617) RGD PMID:8478617 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G LOC134481532 low affinity immunoglobulin gamma Fc region receptor III involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 Ensembl chr13:83,280,790...83,484,920 JBrowse link
G Oscar osteoclast associated Ig-like receptor acts_upstream_of_or_within ISO MGI:5301430 (PMID:21841309) RGD PMID:21841309 NCBI chr 1:65,607,214...65,615,395
Ensembl chr 1:65,607,410...65,613,758 		JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer2 Fc epsilon receptor II involved_in ISO (PMID:7544003) RGD PMID:7544003 NCBI chr12:6,540,697...6,552,364
Ensembl chr12:1,742,815...1,754,476 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:7544003) RGD PMID:7544003 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Myo1g myosin IG involved_in ISO
IEA		 (PMID:23038771)
GO_REF:0000107		 RGD
Ensembl		 PMID:23038771 GO_REF:0000107 NCBI chr14:85,600,619...85,615,760
Ensembl chr14:81,386,701...81,401,843 		JBrowse link
G Nos2 nitric oxide synthase 2 involved_in ISO (PMID:7544003) RGD PMID:7544003 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:25568335) RGD PMID:25568335 NCBI chr16:2,125,234...2,173,457
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO
IEA		 (PMID:25568335)
GO_REF:0000107		 RGD
Ensembl		 PMID:25568335 GO_REF:0000107 NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24586680)		 UniProt
RGD		 PMID:24586680 GO_REF:0000024 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      signal transduction 7313
        cell surface receptor signaling pathway 2915
          immune response-regulating cell surface receptor signaling pathway 330
            Fc receptor signaling pathway 27
              Fc-epsilon receptor signaling pathway + 6
              Fc-gamma receptor signaling pathway + 20
Path 2
Term Annotations click to browse term
  biological_process 20567
    biological regulation 13841
      regulation of biological process 13403
        regulation of cellular process 13038
          signal transduction 7313
            immune response-regulating signaling pathway 559
              immune response-regulating cell surface receptor signaling pathway 330
                Fc receptor signaling pathway 27
                  Fc-epsilon receptor signaling pathway + 6
                  Fc-gamma receptor signaling pathway + 20
paths to the root