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ONTOLOGY REPORT - ANNOTATIONS

Term:signal transduction in absence of ligand
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Accession:GO:0038034 term browser browse the term
Definition:The series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor.
Synonyms:exact_synonym: signal transduction in absence of agonist
 narrow_synonym: basal signaling
 broad_synonym: addiction receptor signaling pathway;   dependence receptor signaling pathway;   non-classical signal transduction
 related_synonym: negative signal transduction


show annotations for term's descendants           Sort by:
extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within ISO MGI:1890081 (PMID:12115603), (PMID:12431371), (PMID:12944463), (PMID:14967141) RGD PMID:12115603 PMID:12431371 PMID:12944463 PMID:14967141 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bag3 BAG cochaperone 3 acts_upstream_of_or_within ISO
IEA		 (PMID:11527400)
GO_REF:0000107		 RGD
Ensembl		 PMID:11527400 GO_REF:0000107 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:1197519|MGI:99702 (PMID:15680329), (PMID:15967824)		 GO_Central
Ensembl
RGD		 PMID:15680329 PMID:15967824 GO_REF:0000033 GO_REF:0000107 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 GO_REF:0000033
MGI:1097161|MGI:1197519 (PMID:15680329), (PMID:15967824)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:15680329 PMID:15967824 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1309517 (PMID:12082633)		 GO_Central
RGD		 PMID:12082633 GO_REF:0000033 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12115603)		 GO_Central
RGD		 PMID:12115603 GO_REF:0000033 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l10 Bcl2-like 10 involved_in
acts_upstream_of		 IBA
ISO		 GO_REF:0000033
(PMID:9878060)		 GO_Central
RGD		 PMID:9878060 GO_REF:0000033 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Bcl2l11 Bcl2-like 11 acts_upstream_of_or_within ISO MGI:1097161|MGI:2156498|MGI:99702 (PMID:15967824) RGD PMID:15967824 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl2l2 Bcl2-like 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12115603)		 GO_Central
RGD		 PMID:12115603 GO_REF:0000033 NCBI chr15:32,326,686...32,337,834
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Casp2 caspase 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:2159368 (PMID:11536012)		 GO_Central
Ensembl
RGD		 PMID:11536012 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Col2a1 collagen type II alpha 1 chain acts_upstream_of ISO
IEA		 MGI:2152978 (PMID:9299161)
GO_REF:0000107		 RGD
Ensembl		 PMID:9299161 GO_REF:0000107 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of ISO
IEA		 MGI:2677796 (PMID:22411810)
GO_REF:0000107		 RGD
Ensembl		 PMID:22411810 GO_REF:0000107 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of ISO
IEA		 (PMID:18322241), (PMID:18971423)
GO_REF:0000107		 RGD
Ensembl		 PMID:18322241 PMID:18971423 GO_REF:0000107 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 involved_in ISO (PMID:17701904) RGD PMID:17701904 NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of ISO MGI:1857803 (PMID:15817220) RGD PMID:15817220 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within ISO
IEA		 (PMID:11700312)
GO_REF:0000107		 RGD
Ensembl		 PMID:11700312 GO_REF:0000107 NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Fadd Fas associated via death domain acts_upstream_of_or_within ISO
IEA		 (PMID:13679421)
GO_REF:0000107		 RGD
Ensembl		 PMID:13679421 GO_REF:0000107 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO MGI:1856334|MGI:1861923 (PMID:13679421) RGD PMID:13679421 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of ISO
IEA		 MGI:1859647 (PMID:16956603)
GO_REF:0000107		 RGD
Ensembl		 PMID:16956603 GO_REF:0000107 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO
IEA		 MGI:1096330 (PMID:12431371)
GO_REF:0000107		 RGD
Ensembl		 PMID:12431371 GO_REF:0000107 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:16543145)		 UniProt
RGD		 PMID:16543145 GO_REF:0000024 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:16543145)		 UniProt
RGD		 PMID:16543145 GO_REF:0000024 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO (PMID:12431371) RGD PMID:12431371 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il1a interleukin 1 alpha acts_upstream_of_or_within ISO MGI:2157371 (PMID:11536012) RGD PMID:11536012 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within ISO
IEA		 MGI:2157396 (PMID:11536012)
GO_REF:0000107		 RGD
Ensembl		 PMID:11536012 GO_REF:0000107 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:12082633) RGD PMID:12082633 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:11527400), (PMID:12124386), (PMID:12944463), (PMID:14967141), (PMID:15231831), (PMID:15680329) RGD PMID:11527400 PMID:12124386 PMID:12944463 PMID:14967141 PMID:15231831 More... NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12115603) RGD PMID:12115603 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Itgav integrin subunit alpha V involved_in ISO
IEA		 (PMID:15591537)
GO_REF:0000107		 RGD
Ensembl		 PMID:15591537 GO_REF:0000107 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO
IEA		 (PMID:15039234)
GO_REF:0000107		 RGD
Ensembl		 PMID:15039234 GO_REF:0000107 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Lcn2 lipocalin 2 acts_upstream_of_or_within ISO
IEA		 (PMID:16377569)
GO_REF:0000107		 RGD
Ensembl		 PMID:16377569 GO_REF:0000107 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:16543145)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:16543145 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 acts_upstream_of_or_within ISO MGI:3052673|MGI:894279 (PMID:17903173) RGD PMID:17903173 NCBI chr 5:134,554,881...134,594,392
Ensembl chr 5:129,318,170...129,357,639 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO
IEA		 MGI:3052675|MGI:894316 (PMID:17903173)
GO_REF:0000107		 RGD
Ensembl		 PMID:17903173 GO_REF:0000107 NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,039,728...9,050,827 		JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:127,647,389...127,649,324
Ensembl chr 6:121,882,366...121,898,643
Ensembl chr17:121,882,366...121,898,643 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of ISO
IEA		 MGI:1857478 (PMID:15039234)
GO_REF:0000107		 RGD
Ensembl		 PMID:15039234 GO_REF:0000107 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Ngf nerve growth factor acts_upstream_of_or_within ISO (PMID:14623868) RGD PMID:14623868 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of ISO
IEA		 (PMID:8206089)
GO_REF:0000107		 RGD
Ensembl		 PMID:8206089 GO_REF:0000107 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr61 G protein-coupled receptor 61 involved_in ISO
IEA		 (PMID:28827538)
GO_REF:0000107		 RGD
Ensembl		 PMID:28827538 GO_REF:0000107 NCBI chr 2:198,471,430...198,477,827
Ensembl chr 2:195,782,752...195,789,621 		JBrowse link
G Gpr62 G protein-coupled receptor 62 involved_in ISO (PMID:28827538) RGD PMID:28827538 NCBI chr 8:115,981,936...115,984,022
Ensembl chr 8:107,103,980...107,105,056 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr 7:64,782,618...64,799,624
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO MGI:99702 (PMID:8358790) RGD PMID:8358790 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Col2a1 collagen type II alpha 1 chain acts_upstream_of_or_within ISO
IEA		 MGI:2152978 (PMID:9299161)
GO_REF:0000107		 RGD
Ensembl		 PMID:9299161 GO_REF:0000107 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO
IEA		 (PMID:10666185)
GO_REF:0000107		 RGD
Ensembl		 PMID:10666185 GO_REF:0000107 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO
IEA		 MGI:2677796 (PMID:22411810)
GO_REF:0000107		 RGD
Ensembl		 PMID:22411810 GO_REF:0000107 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of_or_within ISO
IEA		 (PMID:18322241), (PMID:18971423)
GO_REF:0000107		 RGD
Ensembl		 PMID:18322241 PMID:18971423 GO_REF:0000107 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1857803 (PMID:15817220)		 GO_Central
RGD		 PMID:15817220 GO_REF:0000033 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:144,806,523...144,934,522
Ensembl chr 5:144,806,577...144,934,518 		JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:23,991,431...24,235,132
Ensembl chr 1:22,172,275...22,415,976 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO
IEA		 MGI:1859647 (PMID:16956603)
GO_REF:0000107		 RGD
Ensembl		 PMID:16956603 GO_REF:0000107 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (PMID:15070677) RGD PMID:15070677 NCBI chr17:4,487,716...4,490,701 JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO
IEA		 (PMID:17167422)
GO_REF:0000107		 RGD
Ensembl		 PMID:17167422 GO_REF:0000107 NCBI chr  X:17,193,291...17,209,462
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISO
IEA		 (PMID:10921886)
GO_REF:0000107		 RGD
Ensembl		 PMID:10921886 GO_REF:0000107 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gfral GDNF family receptor alpha like acts_upstream_of_or_within ISO (PMID:16086688) RGD PMID:16086688 NCBI chr 8:85,798,337...85,843,705
Ensembl chr 8:76,918,657...76,959,425 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:8950980) RGD PMID:8950980 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in ISO
IEA		 (PMID:20551324)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551324 GO_REF:0000107 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 8:72,520,616...72,748,395
Ensembl chr 8:63,625,221...63,851,983 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA		 UniProtKB:Q62862 (PMID:20551324)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551324 GO_REF:0000107 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO (PMID:20921992) RGD PMID:20921992 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO (PMID:9115640) RGD PMID:9115640 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:20125124)
GO_REF:0000107		 RGD
Ensembl		 PMID:20125124 GO_REF:0000107 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 acts_upstream_of_or_within ISO
IEA		 (PMID:11050396)
GO_REF:0000107		 RGD
Ensembl		 PMID:11050396 GO_REF:0000107 NCBI chr 5:14,128,628...14,255,099
Ensembl chr 5:9,346,040...9,415,476 		JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:10518215) RGD PMID:10518215 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within ISO
IEA		 (PMID:12574163)
GO_REF:0000107		 RGD
Ensembl		 PMID:12574163 GO_REF:0000107 NCBI chr 9:67,908,277...67,927,224
Ensembl chr 9:60,414,182...60,433,084 		JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO
IEA		 (PMID:10449030)
GO_REF:0000107		 RGD
Ensembl		 PMID:10449030 GO_REF:0000107 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO
IEA		 (PMID:10666185), (PMID:10748004)
GO_REF:0000107		 RGD
Ensembl		 PMID:10666185 PMID:10748004 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in ISO (PMID:18469807) RGD PMID:18469807 NCBI chr20:29,240,639...29,307,270
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO
IEA		 MGI:2677796 (PMID:22411810)
GO_REF:0000107		 RGD
Ensembl		 PMID:22411810 GO_REF:0000107 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Dapk3 death-associated protein kinase 3 involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr 7:9,174,903...9,183,272
Ensembl chr 7:8,524,183...8,532,558 		JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO
IEA		 (PMID:20125124)
GO_REF:0000107		 RGD
Ensembl		 PMID:20125124 GO_REF:0000107 NCBI chr 4:117,114,631...117,117,793
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
ISS
IEA		 (PMID:8267637)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:8267637 GO_REF:0000024 GO_REF:0000107 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (PMID:16020505) RGD PMID:16020505 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within ISO
IEA		 MGI:1857478 (PMID:15039234)
GO_REF:0000107		 RGD
Ensembl		 PMID:15039234 GO_REF:0000107 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha acts_upstream_of_or_within ISO
IEA		 (PMID:12115603)
GO_REF:0000107		 RGD
Ensembl		 PMID:12115603 GO_REF:0000107 NCBI chr 1:210,914,576...210,918,193
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha acts_upstream_of_or_within ISO (PMID:12944463) RGD PMID:12944463 NCBI chr 1:69,213,198...69,232,441
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta involved_in ISO
IEA		 (PMID:21172653)
GO_REF:0000107		 RGD
Ensembl		 PMID:21172653 GO_REF:0000107 NCBI chr 8:60,092,540...60,125,512
Ensembl chr 8:51,186,717...51,228,485 		JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked acts_upstream_of_or_within ISO
IEA		 MGI:3706175 (PMID:17088259)
GO_REF:0000107		 RGD
Ensembl		 PMID:17088259 GO_REF:0000107 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of_or_within ISO
IEA		 (PMID:8206089)
GO_REF:0000107		 RGD
Ensembl		 PMID:8206089 GO_REF:0000107 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr20:29,240,639...29,307,270
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO (PMID:19366691) RGD PMID:19366691 NCBI chr19:59,338,402...60,269,323
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO
IEA		 MGI:2176216|MGI:2181474 (PMID:16207751), (PMID:18191119)
GO_REF:0000107		 RGD
Ensembl		 PMID:16207751 PMID:18191119 GO_REF:0000107 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      signal transduction 7301
        signal transduction in absence of ligand 78
          extrinsic apoptotic signaling pathway in absence of ligand + 76
          ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway 2
          negative regulation of signal transduction in absence of ligand + 35
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        signaling 7862
          signal transduction 7301
            signal transduction in absence of ligand 78
              extrinsic apoptotic signaling pathway in absence of ligand + 76
              ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway 2
              negative regulation of signal transduction in absence of ligand + 35
paths to the root