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ONTOLOGY REPORT - ANNOTATIONS

Term:epidermal growth factor receptor ligand maturation
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Accession:GO:0038004 term browser browse the term
Definition:Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor.
Synonyms:exact_synonym: EGFR ligand maturation
 narrow_synonym: EGFR ligand maturation by peptide bond cleavage;   EGFR ligand processing;   peptide bond cleavage involved in EGFR ligand maturation
 related_synonym: epidermal growth factor receptor ligand processing;   peptide bond cleavage involved in epidermal growth factor receptor ligand maturation
 alt_id: GO:0038005


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epidermal growth factor receptor ligand maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 involved_in IEA
ISO 		GO_REF:0000107
(PMID:14993236), (PMID:17079736) 		Ensembl
RGD		 PMID:14993236 PMID:17079736 GO_REF:0000107 NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
G Mep1a meprin A subunit alpha involved_in ISO (PMID:22923609) RGD PMID:22923609 NCBI chr 9:17,474,634...17,504,147
Ensembl chr 9:17,474,619...17,504,147 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        hormone metabolic process 268
          peptide hormone processing 32
            epidermal growth factor receptor ligand maturation 2
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        macromolecule metabolic process 9981
          macromolecule biosynthetic process 7628
            gene expression 7191
              protein maturation 615
                protein processing 263
                  signaling receptor ligand precursor processing 38
                    peptide hormone processing 32
                      epidermal growth factor receptor ligand maturation 2
paths to the root