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ONTOLOGY REPORT - ANNOTATIONS

Term:Derlin-1 retrotranslocation complex
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Accession:GO:0036513 term browser browse the term
Definition:A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.
Comment:The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.
Synonyms:exact_synonym: Derlin-1 complex;   Derlin-1 protein dislocation complex;   Derlin-1 retro-translocation complex;   Derlin-1 retrotranslocon;   ERAD protein dislocation complex


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Derlin-1 retrotranslocation complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMFR autocrine motility factor receptor part_of IEA Ensembl GO_REF:0000107 NCBI chr16:36,647,792...36,711,782
Ensembl chr16:55,780,633...55,843,744 		JBrowse link
G DERL1 derlin 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 8:119,707,397...119,736,502
Ensembl chr 8:122,463,063...122,492,137 		JBrowse link
G HM13 histocompatibility minor 13 part_of IEA Ensembl GO_REF:0000107 NCBI chr20:27,803,597...27,859,384
Ensembl chr20:28,441,285...28,501,001 		JBrowse link
G RNF139 ring finger protein 139 part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:121,158,715...121,172,069
Ensembl chr 8:123,912,589...123,924,720 		JBrowse link
G SEL1L SEL1L adaptor subunit of SYVN1 ubiquitin ligase part_of IEA Ensembl GO_REF:0000107 NCBI chr14:62,050,695...62,111,489
Ensembl chr14:81,248,441...81,309,597 		JBrowse link
G SELENOS selenoprotein S part_of IEA TreeGrafter GO_REF:0000118 NCBI chr15:79,995,678...80,002,159
Ensembl chr15:99,279,203...99,285,682 		JBrowse link
G SYVN1 synoviolin 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr11:60,489,626...60,496,945
Ensembl chr11:63,829,138...63,834,364 		JBrowse link
G VCP valosin containing protein part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:34,907,147...34,923,227
Ensembl chr 9:35,712,937...35,729,588 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20330
    protein-containing complex 7920
      endoplasmic reticulum protein-containing complex 120
        Derlin-1 retrotranslocation complex 8
Path 2
Term Annotations click to browse term
  cellular_component 20330
    cellular anatomical structure 19896
      organelle 14817
        intracellular organelle 14397
          intracellular membrane-bounded organelle 12792
            endoplasmic reticulum 1617
              endoplasmic reticulum subcompartment 847
                endoplasmic reticulum membrane 837
                  Derlin-1 retrotranslocation complex 8
paths to the root