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ONTOLOGY REPORT - ANNOTATIONS

Term:aggrephagy
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Accession:GO:0035973 term browser browse the term
Definition:The selective degradation of protein aggregates by macroautophagy.
Synonyms:alt_id: GO:0035972
 xref: Reactome:R-HSA-9646399 "Aggrephagy"


show annotations for term's descendants           Sort by:
aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07040864.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Atg4a autophagy related 4A, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:104,665,345...104,765,271
Ensembl chr  X:104,665,345...104,765,268 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103 		JBrowse link
G Atg4c autophagy related 4C, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:113,867,092...113,934,830 		JBrowse link
G Atg4d autophagy related 4D, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:19,807,733...19,817,321
Ensembl chr 8:19,807,766...19,817,321 		JBrowse link
G Atg5 autophagy related 5 involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:22982048)		 Ensembl
GO_Central
RGD		 PMID:22982048 GO_REF:0000033 GO_REF:0000107 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Sqstm1 sequestosome 1 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:25723488), (PMID:33397898)
GO_REF:0000033
UniProtKB:Q562E7 (PMID:17580304), (PMID:22017874), (PMID:28404643), (PMID:29343546), (PMID:29507397), (PMID:31857589), (PMID:37306101), (PMID:37802024)		 UniProt
Ensembl
RGD
GO_Central		 PMID:17580304 PMID:22017874 PMID:25723488 PMID:28404643 PMID:29343546 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:21143716)		 Ensembl
UniProt
RGD		 PMID:21143716 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,438,456...6,482,498
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
G Wdfy3 WD repeat and FYVE domain containing 3 involved_in ISO
IEA
IBA		 (PMID:20168092), (PMID:20417604)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:20168092 PMID:20417604 GO_REF:0000033 GO_REF:0000107 NCBI chr14:7,578,245...7,810,491
Ensembl chr14:7,606,628...7,810,482 		JBrowse link
G Wdr81 WD repeat domain 81 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:28404643)		 UniProt
GO_Central
Ensembl
RGD		 PMID:28404643 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:60,281,969...60,295,374
Ensembl chr10:60,281,972...60,295,296 		JBrowse link
negative regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 involved_in ISO
IEA		 (PMID:31857589)
GO_REF:0000107		 RGD
Ensembl		 PMID:31857589 GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Lypla1 lysophospholipase 1 involved_in ISO
IEA		 (PMID:37802024)
GO_REF:0000107		 RGD
Ensembl		 PMID:37802024 GO_REF:0000107 NCBI chr 5:14,679,605...14,708,774
Ensembl chr 5:14,679,606...14,708,746 		JBrowse link
positive regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BAG cochaperone 3 involved_in ISO
IEA		 (PMID:18006506)
GO_REF:0000107		 RGD
Ensembl		 PMID:18006506 GO_REF:0000107 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22017874)		 UniProt
RGD		 PMID:22017874 GO_REF:0000024 NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Hspb8 heat shock protein family B (small) member 8 involved_in ISO
IEA		 (PMID:18006506)
GO_REF:0000107		 RGD
Ensembl		 PMID:18006506 GO_REF:0000107 NCBI chr12:45,835,899...45,866,449
Ensembl chr12:40,176,532...40,191,185 		JBrowse link
G Htt huntingtin involved_in IEA
ISO		 GO_REF:0000107
(PMID:25686248)		 Ensembl
RGD		 PMID:25686248 GO_REF:0000107 NCBI chr14:80,070,456...80,219,668
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:31857589)		 Ensembl
RGD		 PMID:31857589 GO_REF:0000107 NCBI chr 1:212,325,089...212,332,640
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Zdhhc19 zinc finger DHHC-type palmitoyltransferase 19 involved_in ISO
IEA		 (PMID:37802024)
GO_REF:0000107		 RGD
Ensembl		 PMID:37802024 GO_REF:0000107 NCBI chr11:81,782,899...81,794,105
Ensembl chr11:68,277,848...68,288,954 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      process utilizing autophagic mechanism 558
        autophagy 558
          macroautophagy 335
            aggrephagy 18
              negative regulation of aggrephagy 2
              positive regulation of aggrephagy 6
              regulation of aggrephagy + 8
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        catabolic process 2956
          autophagy 558
            macroautophagy 335
              aggrephagy 18
                negative regulation of aggrephagy 2
                positive regulation of aggrephagy 6
                regulation of aggrephagy + 8
paths to the root