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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


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regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828 		JBrowse link
G SPNS1 SPNS lysolipid transporter 1, lysophospholipid involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:36161949) Ensembl
MGI		 PMID:36161949 GO_REF:0000107 NCBI chr 3:18,629,646...18,638,442
Ensembl chr 3:18,629,646...18,639,214 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:26,363,808...26,384,933
Ensembl chr  X:26,365,027...26,384,760 		JBrowse link
G TMEM165 transmembrane protein 165 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,751,570...54,796,352
Ensembl chr 8:54,751,572...54,787,886 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:295,693...313,974
Ensembl chr 8:297,007...313,972 		JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:30,469,003...30,496,626
Ensembl chr14:30,469,070...30,495,470 		JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:36,271,154...36,300,240
Ensembl chr  X:36,271,223...36,300,240 		JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:31,974,715...31,979,062
Ensembl chr15:31,974,724...31,979,059 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,836...18,450,290 		JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:49,105,822...49,128,425
Ensembl chr11:49,105,878...49,129,886 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:166,107,895...166,126,054
Ensembl chr 1:166,107,228...166,126,808 		JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33966596) Ensembl
MGI		 PMID:33966596 GO_REF:0000107 NCBI chr 4:83,458,358...83,469,931
Ensembl chr 4:83,458,242...83,469,930 		JBrowse link
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:18,893,772...18,900,444
Ensembl chr12:18,893,770...18,900,446 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:78,600,818...78,617,587
Ensembl chr11:78,600,645...78,617,616 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:98,586,718...98,623,939
Ensembl chr  X:98,581,992...98,623,940 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:95,840,906...95,860,858
Ensembl chr 6:95,840,908...95,860,858 		JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20920792) Ensembl
MGI		 PMID:20920792 GO_REF:0000107 NCBI chr 4:95,987,524...95,989,527
Ensembl chr 4:95,984,358...95,989,474 		JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chr 9:81,837,654...81,864,215
Ensembl chr 9:81,837,667...81,864,210 		JBrowse link
G TMEM199 transmembrane protein 199 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:44,636,379...44,641,536
Ensembl chr12:44,636,379...44,641,527 		JBrowse link
G TMEM9 transmembrane protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:23,586,487...23,600,042
Ensembl chr10:23,586,491...23,607,530 		JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMACR alpha-methylacyl-CoA racemase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:20,005,741...20,023,339
Ensembl chr16:19,956,366...20,023,289 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,836...18,450,290 		JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:56,657,648...56,869,920
Ensembl chr15:56,657,616...56,869,918 		JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:19,958,315...20,002,198
Ensembl chr16:19,956,366...20,023,289 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:295,693...313,974
Ensembl chr 8:297,007...313,972 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18943
    biological regulation 13022
      regulation of biological quality 3268
        regulation of intracellular pH 81
          regulation of lysosomal lumen pH 23
            lysosomal lumen acidification 14
            lysosomal lumen pH elevation 5
Path 2
Term Annotations click to browse term
  biological_process 18943
    cellular process 18484
      cellular component organization or biogenesis 7489
        cellular component organization 7283
          organelle organization 3517
            vacuole organization 224
              lytic vacuole organization 92
                lysosome organization 92
                  regulation of lysosomal lumen pH 23
                    lysosomal lumen acidification 14
                    lysosomal lumen pH elevation 5
paths to the root