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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.

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regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:22012985) ParkinsonsUK-UCL PMID:22012985 NCBI chrNW_004624778:106,594...279,325
Ensembl chrNW_004624778:108,761...279,230 		JBrowse link
G Spns1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624782:12,799,850...12,807,159
Ensembl chrNW_004624782:12,799,038...12,807,121 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624762:25,427,519...25,448,180
Ensembl chrNW_004624762:25,430,926...25,448,114 		JBrowse link
G Tmem165 transmembrane protein 165 involved_in ISO (PMID:23569283) UniProt PMID:23569283 NCBI chrNW_004624761:14,039,698...14,066,750
Ensembl chrNW_004624761:14,038,758...14,066,894 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO (PMID:35750034)
(PMID:26317472)		 UniProt PMID:26317472 PMID:35750034 NCBI chrNW_004624755:26,190,547...26,200,512
Ensembl chrNW_004624755:26,190,547...26,207,793 		JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624747:22,458,098...22,478,735
Ensembl chrNW_004624747:22,461,346...22,478,867 		JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624762:14,952,313...14,975,678
Ensembl chrNW_004624762:14,952,002...14,975,900 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624782:12,995,277...13,004,980
Ensembl chrNW_004624782:12,995,277...13,005,087 		JBrowse link
G Cln5 CLN5 intracellular trafficking protein involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004624751:23,395,284...23,404,798
Ensembl chrNW_004624751:23,396,789...23,404,906 		JBrowse link
G Cln6 CLN6 transmembrane ER protein involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004624781:4,866,896...4,879,321
Ensembl chrNW_004624781:4,866,927...4,879,321 		JBrowse link
G Creg1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) MGI PMID:33966596 NCBI chrNW_004624826:5,593,190...5,605,946
Ensembl chrNW_004624826:5,589,791...5,605,893 		JBrowse link
G Grn granulin precursor involved_in ISO (PMID:28073925) UniProt PMID:28073925 NCBI chrNW_004624795:704,066...708,721
Ensembl chrNW_004624795:704,252...707,165 		JBrowse link
G Lamp1 lysosomal associated membrane protein 1 involved_in ISO (PMID:37390818) UniProt PMID:37390818 NCBI chrNW_004624793:661,322...675,603
Ensembl chrNW_004624793:661,342...675,675 		JBrowse link
G Lamp2 lysosomal associated membrane protein 2 involved_in ISO (PMID:37390818) UniProt PMID:37390818 NCBI chrNW_004624931:297,864...343,314
Ensembl chrNW_004624931:298,328...343,915 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004624764:22,542,892...22,577,077
Ensembl chrNW_004624764:22,543,857...22,577,121 		JBrowse link
G Snapin SNAP associated protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624885:3,490,321...3,491,963
Ensembl chrNW_004624885:3,490,321...3,491,946 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624827:7,015,267...7,043,853
Ensembl chrNW_004624827:7,014,842...7,041,871 		JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053) UniProt PMID:30374053 NCBI chrNW_004624807:9,525,770...9,544,757
Ensembl chrNW_004624807:9,525,855...9,544,757 		JBrowse link
G Vma12 vacuolar ATPase assembly factor VMA12 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:961,888...965,911
Ensembl chrNW_004624786:961,890...966,430 		JBrowse link
G Vma22 vacuolar ATPase assembly factor VMA22 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chrNW_004624732:14,469,377...14,474,540
Ensembl chrNW_004624732:14,466,079...14,474,561 		JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624782:12,995,277...13,004,980
Ensembl chrNW_004624782:12,995,277...13,005,087 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO (PMID:25513726), (PMID:32966160) UniProt PMID:25513726 PMID:32966160 NCBI chrNW_004624896:2,163,043...2,432,016
Ensembl chrNW_004624896:2,163,468...2,415,432 		JBrowse link
G Slc45a2 solute carrier family 45 member 2 involved_in ISO (PMID:32966160)
(PMID:35469906)		 UniProt PMID:32966160 PMID:35469906 NCBI chrNW_004624759:20,640,407...20,701,790
Ensembl chrNW_004624759:20,673,033...20,701,361 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO (PMID:35333573), (PMID:35750034), (PMID:37390818) UniProt PMID:35333573 PMID:35750034 PMID:37390818 NCBI chrNW_004624755:26,190,547...26,200,512
Ensembl chrNW_004624755:26,190,547...26,207,793 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17650
    biological regulation 11838
      regulation of biological quality 3017
        regulation of intracellular pH 78
          regulation of lysosomal lumen pH 22
            lysosomal lumen acidification 14
            lysosomal lumen pH elevation 4
Path 2
Term Annotations click to browse term
  biological_process 17650
    cellular process 17226
      cellular component organization or biogenesis 7005
        cellular component organization 6802
          organelle organization 3445
            vacuole organization 219
              lytic vacuole organization 95
                lysosome organization 95
                  regulation of lysosomal lumen pH 22
                    lysosomal lumen acidification 14
                    lysosomal lumen pH elevation 4
paths to the root