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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


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regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine-rich repeat kinase 2 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323 		JBrowse link
G Spns1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within IMP (PMID:36161949) MGI PMID:36161949 NCBI chr 7:125,969,232...125,977,179
Ensembl chr 7:125,969,232...125,976,622 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IBA
ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr  X:84,820,445...84,935,105
Ensembl chr  X:84,913,960...84,935,105 		JBrowse link
G Tmem165 transmembrane protein 165 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 5:76,331,727...76,357,091
Ensembl chr 5:76,331,727...76,357,092 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO
IMP		 (PMID:26317472) GO_Central
UniProt		 PMID:26317472 GO_REF:0000119 NCBI chr 5:108,777,649...108,795,636
Ensembl chr 5:108,777,636...108,796,648 		JBrowse link
G Vps33a VPS33A CORVET/HOPS core subunit involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 5:123,666,820...123,711,104
Ensembl chr 5:123,666,722...123,711,101 		JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr  X:12,453,998...12,483,290
Ensembl chr  X:12,454,040...12,483,288 		JBrowse link
G Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C acts_upstream_of_or_within TAS (PMID:11441017) MGI PMID:11441017 NCBI chr17:24,382,839...24,388,652
Ensembl chr17:24,382,840...24,388,676 		JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 1:34,475,751...34,478,753
Ensembl chr 1:34,475,751...34,478,753 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 7:126,170,571...126,184,991
Ensembl chr 7:126,170,379...126,184,989 		JBrowse link
G Cln5 ceroid-lipofuscinosis, neuronal 5 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr14:103,307,679...103,315,064
Ensembl chr14:103,307,652...103,315,064 		JBrowse link
G Cln6 ceroid-lipofuscinosis, neuronal 6 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 9:62,746,067...62,759,288
Ensembl chr 9:62,746,067...62,759,288 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 acts_upstream_of_or_within IMP (PMID:33966596) MGI PMID:33966596 NCBI chr 1:165,591,327...165,602,878
Ensembl chr 1:165,591,315...165,602,877 		JBrowse link
G Grn granulin involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:102,321,333...102,327,635
Ensembl chr11:102,321,141...102,327,874 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr  X:37,488,524...37,545,337
Ensembl chr  X:37,490,234...37,545,331 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 4:122,729,879...122,752,968
Ensembl chr 4:122,730,035...122,752,968 		JBrowse link
G Snapin SNAP-associated protein acts_upstream_of_or_within IMP (PMID:20920792) MGI PMID:20920792 NCBI chr 3:90,395,333...90,398,320
Ensembl chr 3:90,395,333...90,398,340 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within IMP (PMID:28728022) MGI PMID:28728022 NCBI chr 6:13,069,758...13,089,268
Ensembl chr 6:13,069,758...13,089,268 		JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:78,397,881...78,402,994
Ensembl chr11:78,397,881...78,402,998 		JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 1:135,935,957...135,962,768
Ensembl chr 1:135,935,888...135,963,080 		JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 7:126,170,571...126,184,991
Ensembl chr 7:126,170,379...126,184,989 		JBrowse link
G Oca2 oculocutaneous albinism II involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 7:55,889,341...56,186,266
Ensembl chr 7:55,889,508...56,186,266 		JBrowse link
G Slc45a2 solute carrier family 45, member 2 involved_in ISO
ISS
IMP		 (PMID:35469906) GO_Central
UniProt		 PMID:35469906 GO_REF:0000024 GO_REF:0000119 NCBI chr15:11,000,807...11,029,319
Ensembl chr15:11,000,807...11,029,319 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 5:108,777,649...108,795,636
Ensembl chr 5:108,777,636...108,796,648 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28630
    biological regulation 13466
      regulation of biological quality 3585
        regulation of intracellular pH 83
          regulation of lysosomal lumen pH 23
            lysosomal lumen acidification 15
            lysosomal lumen pH elevation 4
Path 2
Term Annotations click to browse term
  biological_process 28630
    cellular process 18394
      cellular component organization or biogenesis 7337
        cellular component organization 7126
          organelle organization 3746
            vacuole organization 243
              lytic vacuole organization 104
                lysosome organization 104
                  regulation of lysosomal lumen pH 23
                    lysosomal lumen acidification 15
                    lysosomal lumen pH elevation 4
paths to the root