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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


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regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870 		JBrowse link
G SPNS1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within ISO (PMID:36161949) MGI PMID:36161949 NCBI chr 6:18,450,019...18,458,456
Ensembl chr 6:18,412,219...18,459,438 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:31001245) UniProt PMID:31001245 NCBI chr  X:25,664,361...25,679,044 JBrowse link
G TMEM165 transmembrane protein 165 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:47,658,408...47,683,519
Ensembl chr13:47,658,330...47,682,866 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,554,001...91,576,845
Ensembl chr 3:91,553,778...91,670,930 		JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:7,090,669...7,119,913 JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:35,050,588...35,073,633
Ensembl chr  X:35,050,606...35,073,067 		JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chr25:19,027,014...19,031,467
Ensembl chr25:19,027,342...19,030,887 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033 		JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr22:30,568,572...30,575,890
Ensembl chr22:30,568,572...30,575,890 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr30:32,246,394...32,264,251
Ensembl chr30:32,246,411...32,264,240 		JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:30,873,556...30,884,257
Ensembl chr 7:30,873,556...30,883,370 		JBrowse link
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:60,678,116...60,695,619
Ensembl chr22:60,678,111...60,694,924 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:92,405,946...92,444,527
Ensembl chr  X:92,407,950...92,444,765 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:2,815,428...2,886,474
Ensembl chr15:2,859,979...2,894,425 		JBrowse link
G SNAPIN SNAP associated protein acts_upstream_of_or_within ISO (PMID:20920792) MGI PMID:20920792 NCBI chr 7:43,410,554...43,411,929
Ensembl chr 7:43,410,998...43,412,323 		JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chr14:27,140,692...27,166,652
Ensembl chr14:27,140,687...27,161,333 		JBrowse link
G TMEM199 transmembrane protein 199 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:42,607,688...42,614,776
Ensembl chr 9:42,607,733...42,611,445 		JBrowse link
G TMEM9 transmembrane protein 9 involved_in ISO (PMID:30374053) UniProt PMID:30374053 NCBI chr 7:2,069,017...2,087,961 JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMACR alpha-methylacyl-CoA racemase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:73,815,438...73,836,016
Ensembl chr 4:73,815,291...73,867,437 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033 		JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:32,361,825...32,713,631
Ensembl chr 3:32,361,517...32,713,572 		JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:73,838,684...73,868,222
Ensembl chr 4:73,815,291...73,867,437 		JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,554,001...91,576,845
Ensembl chr 3:91,553,778...91,670,930 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22141
    biological regulation 12559
      regulation of biological quality 3369
        regulation of intracellular pH 84
          regulation of lysosomal lumen pH 23
            lysosomal lumen acidification 14
            lysosomal lumen pH elevation 5
Path 2
Term Annotations click to browse term
  biological_process 22141
    cellular process 21672
      cellular component organization or biogenesis 10063
        cellular component organization 9831
          organelle organization 3649
            vacuole organization 233
              lytic vacuole organization 95
                lysosome organization 95
                  regulation of lysosomal lumen pH 23
                    lysosomal lumen acidification 14
                    lysosomal lumen pH elevation 5
paths to the root