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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.

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regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:22012985) ParkinsonsUK-UCL PMID:22012985 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923 		JBrowse link
G Spns1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within ISO (PMID:36161949) MGI PMID:36161949 NCBI chrNW_004955493:6,506,449...6,514,308
Ensembl chrNW_004955493:6,505,230...6,514,307 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:31001245) UniProt PMID:31001245 NCBI chrNW_004955531:207,614...293,127
Ensembl chrNW_004955531:267,216...293,127 		JBrowse link
G Tmem165 transmembrane protein 165 involved_in ISO (PMID:23569283) UniProt PMID:23569283 NCBI chrNW_004955447:15,538,958...15,543,885
Ensembl chrNW_004955447:15,538,958...15,543,892 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO (PMID:26317472)
(PMID:35750034)		 UniProt PMID:26317472 PMID:35750034 NCBI chrNW_004955514:434,283...453,239
Ensembl chrNW_004955514:434,285...453,239 		JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in ISO (PMID:28013294) UniProt PMID:28013294 NCBI chrNW_004955482:6,333,282...6,352,369
Ensembl chrNW_004955482:6,332,366...6,353,834 		JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO (PMID:32276428) UniProt PMID:32276428 NCBI chrNW_004955565:2,006,154...2,029,921 JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004955493:6,696,520...6,707,849
Ensembl chrNW_004955493:6,696,241...6,707,849 		JBrowse link
G Cln5 CLN5 intracellular trafficking protein involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004955404:30,229,632...30,235,677
Ensembl chrNW_004955404:30,229,632...30,235,679 		JBrowse link
G Cln6 CLN6 transmembrane ER protein involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004955450:7,876,572...7,885,305
Ensembl chrNW_004955450:7,876,522...7,886,581 		JBrowse link
G Creg1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) MGI PMID:33966596 NCBI chrNW_004955462:9,440,019...9,451,875
Ensembl chrNW_004955462:9,439,987...9,455,268 		JBrowse link
G Grn granulin precursor involved_in ISO (PMID:28073925) UniProt PMID:28073925 NCBI chrNW_004955451:17,368,600...17,371,981
Ensembl chrNW_004955451:17,368,428...17,372,377 		JBrowse link
G Lamp1 lysosomal associated membrane protein 1 involved_in ISO (PMID:37390818) UniProt PMID:37390818 NCBI chrNW_004955404:557,090...573,532
Ensembl chrNW_004955404:557,862...573,379 		JBrowse link
G Lamp2 lysosomal associated membrane protein 2 involved_in ISO (PMID:37390818) UniProt PMID:37390818 NCBI chrNW_004955572:1,423,048...1,464,443
Ensembl chrNW_004955572:1,422,981...1,462,622 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO (PMID:11722572) UniProt PMID:11722572 NCBI chrNW_004955452:17,518,345...17,549,112
Ensembl chrNW_004955452:17,529,115...17,549,664 		JBrowse link
G Snapin SNAP associated protein acts_upstream_of_or_within ISO (PMID:20920792) MGI PMID:20920792 NCBI chrNW_004955545:306,546...308,229
Ensembl chrNW_004955545:306,546...308,229 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chrNW_004955432:18,619,418...18,644,876
Ensembl chrNW_004955432:18,619,413...18,639,151 		JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053) UniProt PMID:30374053 NCBI chrNW_004955406:37,279,885...37,299,196
Ensembl chrNW_004955406:37,279,694...37,314,251 		JBrowse link
G Vma12 vacuolar ATPase assembly factor VMA12 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chrNW_004955481:4,772,394...4,776,524
Ensembl chrNW_004955481:4,772,401...4,776,524 		JBrowse link
G Vma22 vacuolar ATPase assembly factor VMA22 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chrNW_004955459:25,649...30,215
Ensembl chrNW_004955459:25,649...30,215 		JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) UniProt PMID:10924275 NCBI chrNW_004955493:6,696,520...6,707,849
Ensembl chrNW_004955493:6,696,241...6,707,849 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO (PMID:25513726), (PMID:32966160) UniProt PMID:25513726 PMID:32966160 NCBI chrNW_004955533:1,522,878...1,796,673
Ensembl chrNW_004955533:1,522,795...1,797,116 		JBrowse link
G Slc45a2 solute carrier family 45 member 2 involved_in ISO (PMID:35469906)
(PMID:32966160)		 UniProt PMID:32966160 PMID:35469906 NCBI chrNW_004955426:19,498,942...19,530,628
Ensembl chrNW_004955426:19,498,942...19,530,628 		JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISO (PMID:35333573), (PMID:35750034), (PMID:37390818) UniProt PMID:35333573 PMID:35750034 PMID:37390818 NCBI chrNW_004955514:434,283...453,239
Ensembl chrNW_004955514:434,285...453,239 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12619
    biological regulation 9092
      regulation of biological quality 2713
        regulation of intracellular pH 65
          regulation of lysosomal lumen pH 22
            lysosomal lumen acidification 14
            lysosomal lumen pH elevation 4
Path 2
Term Annotations click to browse term
  biological_process 12619
    cellular process 12054
      cellular component organization or biogenesis 5425
        cellular component organization 5295
          organelle organization 2900
            vacuole organization 193
              lytic vacuole organization 87
                lysosome organization 87
                  regulation of lysosomal lumen pH 22
                    lysosomal lumen acidification 14
                    lysosomal lumen pH elevation 4
paths to the root