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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


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regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:22012985) RGD PMID:22012985 NCBI chr 7:124,706,246...124,867,234 JBrowse link
G Spns1 SPNS lysolipid transporter 1, lysophospholipid involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:36161949)		 Ensembl
RGD		 PMID:36161949 GO_REF:0000107 NCBI chr 1:180,942,088...180,949,415 JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO
IBA		 (PMID:31001245)
GO_REF:0000033		 RGD
GO_Central		 PMID:31001245 GO_REF:0000033 NCBI chr  X:50,403,962...50,423,141 JBrowse link
G Tmem165 transmembrane protein 165 involved_in ISO
ISS		 (PMID:23569283)
GO_REF:0000024		 RGD
UniProt		 PMID:23569283 GO_REF:0000024 NCBI chr14:31,993,489...32,018,717 JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26317472)
(PMID:35750034)		 UniProt
RGD		 PMID:26317472 PMID:35750034 GO_REF:0000024 NCBI chr14:1,073,410...1,089,764 JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in ISO
ISS
IEA		 (PMID:28013294)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:28013294 GO_REF:0000024 GO_REF:0000107 NCBI chr12:33,024,596...33,051,399 JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO
IEA
ISS		 (PMID:32276428)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:32276428 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:10,183,983...10,210,948 JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348 JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO
IBA		 (PMID:11722572)
GO_REF:0000033		 RGD
GO_Central		 PMID:11722572 GO_REF:0000033 NCBI chr 1:181,156,071...181,169,458 JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:79,893,573...79,903,438 JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr 8:63,303,356...63,318,360 JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 acts_upstream_of_or_within ISO (PMID:33966596) RGD PMID:33966596 NCBI chr13:80,552,779...80,565,272 JBrowse link
G Grn granulin precursor involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:28073925)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28073925 GO_REF:0000024 GO_REF:0000107 NCBI chr10:87,387,672...87,393,777 JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:37390818)		 Ensembl
UniProt
RGD		 PMID:37390818 GO_REF:0000024 GO_REF:0000107 NCBI chr16:83,058,131...83,082,843 JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:37390818)		 Ensembl
UniProt
RGD		 PMID:37390818 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:122,038,734...122,087,745 JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO
ISS		 (PMID:11722572)
PMID:8895569		 RGD PMID:11722572 PMID:8895569 RGD:8553248 NCBI chr 5:135,121,164...135,142,048 JBrowse link
G Snapin SNAP-associated protein acts_upstream_of_or_within ISO MGI:3608768 (PMID:20920792) RGD PMID:20920792 NCBI chr 2:175,971,575...175,974,164 JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (PMID:28728022) RGD PMID:28728022 NCBI chr 4:41,328,125...41,347,315 JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISO
IEA
ISS		 (PMID:28296633)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28296633 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,402,493...63,407,065 JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053) RGD PMID:30374053 NCBI chr13:50,008,829...50,027,556 JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) RGD PMID:10924275 NCBI chr 1:181,156,071...181,169,458 JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO (PMID:25513726), (PMID:32966160) RGD PMID:25513726 PMID:32966160 NCBI chr 1:107,116,278...107,446,093 JBrowse link
G Slc45a2 solute carrier family 45, member 2 involved_in ISO (PMID:32966160)
(PMID:35469906)		 RGD PMID:32966160 PMID:35469906 NCBI chr 2:59,963,599...59,996,408 JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISS
ISO		 GO_REF:0000024
(PMID:35333573), (PMID:35750034), (PMID:37390818)		 UniProt
RGD		 PMID:35333573 PMID:35750034 PMID:37390818 GO_REF:0000024 NCBI chr14:1,073,410...1,089,764 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    biological regulation 13821
      regulation of biological quality 3448
        regulation of intracellular pH 83
          regulation of lysosomal lumen pH 22
            lysosomal lumen acidification 14
            lysosomal lumen pH elevation 4
Path 2
Term Annotations click to browse term
  biological_process 20534
    cellular process 19523
      cellular component organization or biogenesis 7187
        cellular component organization 6903
          organelle organization 3691
            vacuole organization 234
              lytic vacuole organization 92
                lysosome organization 92
                  regulation of lysosomal lumen pH 22
                    lysosomal lumen acidification 14
                    lysosomal lumen pH elevation 4
paths to the root