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ONTOLOGY REPORT - ANNOTATIONS

Term:mitochondrial prohibitin complex
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Accession:GO:0035632 term browser browse the term
Definition:A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.
Synonyms:exact_synonym: mitochondrial inner membrane prohibitin complex


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mitochondrial prohibitin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phb1 prohibitin 1 part_of ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20959514)
(PMID:20959514), (PMID:31522117)		 UniProt
Ensembl
RGD		 PMID:20959514 PMID:31522117 GO_REF:0000024 GO_REF:0000107 NCBI chr10:81,102,043...81,114,815
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phb2 prohibitin 2 part_of IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:20959514), (PMID:31522117)		 Ensembl
UniProt
RGD		 PMID:20959514 PMID:31522117 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:159,203,948...159,208,561
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21364
    protein-containing complex 6830
      mitochondrial protein-containing complex 183
        inner mitochondrial membrane protein complex 55
          mitochondrial prohibitin complex 2
Path 2
Term Annotations click to browse term
  cellular_component 21364
    cellular anatomical structure 21069
      organelle 14290
        intracellular organelle 13880
          intracellular membrane-bounded organelle 12307
            mitochondrion 2009
              mitochondrial envelope 839
                mitochondrial membrane 783
                  mitochondrial inner membrane 485
                    inner mitochondrial membrane protein complex 55
                      mitochondrial prohibitin complex 2
paths to the root