ONTOLOGY REPORT - ANNOTATIONS
Term: ectopic germ cell programmed cell death
Accession: GO:0035234
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Definition: Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.
Synonyms: exact_synonym: programmed cell death of ectopic germ cells; programmed cell death, ectopic germ cells
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Bax
BCL2 associated X, apoptosis regulator
acts_upstream_of_or_within
ISO IEA
MGI:1857429|MGI:96677|MGI:96974 (PMID:14660547), (PMID:17107997) MGI:1857429 (PMID:9988273) GO_REF:0000107
RGD Ensembl
PMID:9988273 PMID:14660547 PMID:17107997
GO_REF:0000107
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
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Bcl2l1
Bcl2-like 1
acts_upstream_of
ISO
MGI:2176699 (PMID:10894153)
RGD
PMID:10894153
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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Casp2
caspase 2
acts_upstream_of_or_within
ISO IEA
MGI:107700 (PMID:11536012) GO_REF:0000107
RGD Ensembl
PMID:11536012
GO_REF:0000107
NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:71,149,669...71,167,379
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Casp4
caspase 4
acts_upstream_of_or_within
ISO
MGI:2159366|MGI:97295 (PMID:11536012)
RGD
PMID:11536012
NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:2,598,876...2,635,092
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Ddb1
damage-specific DNA binding protein 1
acts_upstream_of
ISO
MGI:3698413 (PMID:24357321)
RGD
PMID:24357321
NCBI chr 1:216,677,810...216,703,605
Ensembl chr 1:207,252,890...207,278,676
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Il1a
interleukin 1 alpha
acts_upstream_of_or_within
ISO
MGI:96543 (PMID:11536012)
RGD
PMID:11536012
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
acts_upstream_of_or_within
ISO IEA
MGI:96542 (PMID:11536012) GO_REF:0000107
RGD Ensembl
PMID:11536012
GO_REF:0000107
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
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Insl6
insulin-like 6
acts_upstream_of
ISO
MGI:4431170 (PMID:19520787)
RGD
PMID:19520787
NCBI chr 1:236,483,530...236,487,065
Ensembl chr 1:227,069,958...227,073,493
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Kit
KIT proto-oncogene receptor tyrosine kinase
acts_upstream_of acts_upstream_of_or_within
ISO IEA
MGI:1856232 (PMID:18308723) MGI:99702 (PMID:14660547) GO_REF:0000107
RGD Ensembl
PMID:14660547 PMID:18308723
GO_REF:0000107
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,548,877...32,624,652
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Kitlg
KIT ligand
acts_upstream_of_or_within
ISO IEA
MGI:1856161 (PMID:17107997) GO_REF:0000107
RGD Ensembl
PMID:17107997
GO_REF:0000107
NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:34,896,053...34,977,214
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Lrriq1
leucine-rich repeats and IQ motif containing 1
acts_upstream_of_or_within
ISO
(PMID:36129630)
RGD
PMID:36129630
NCBI chr 7:40,211,036...40,296,374
Ensembl chr 7:38,192,759...38,409,901
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Mael
maelstrom spermatogenic transposon silencer
acts_upstream_of
ISO
MGI:3795667 (PMID:18694567)
RGD
PMID:18694567
NCBI chr13:80,990,040...81,029,623
Ensembl chr13:78,457,073...78,496,657
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Prkdc
protein kinase, DNA-activated, catalytic subunit
acts_upstream_of_or_within
ISO IEA
MGI:2667593 (PMID:17145779) GO_REF:0000107
RGD Ensembl
PMID:17145779
GO_REF:0000107
NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952
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Sod1
superoxide dismutase 1
acts_upstream_of
ISO IEA
MGI:1857873 (PMID:16036348) GO_REF:0000107
RGD Ensembl
PMID:16036348
GO_REF:0000107
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
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Syce3
synaptonemal complex central element protein 3
acts_upstream_of
ISO IEA
(PMID:20407872) GO_REF:0000107
RGD Ensembl
PMID:20407872
GO_REF:0000107
NCBI chr 7:122,336,427...122,362,608
Ensembl chr 7:120,456,800...120,482,973
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Sycp2
synaptonemal complex protein 2
acts_upstream_of
ISO IEA
MGI:3526164 (PMID:16717126) GO_REF:0000107
RGD Ensembl
PMID:16717126
GO_REF:0000107
NCBI chr 3:185,814,033...185,876,516
Ensembl chr 3:165,436,331...165,498,789
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Tex11
testis expressed 11
acts_upstream_of
ISO
MGI:3526163 (PMID:18316482)
RGD
PMID:18316482
NCBI chr X:69,973,012...70,236,544
Ensembl chr X:65,932,988...66,196,187
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Topaz1
testis and ovary specific TOPAZ 1
acts_upstream_of_or_within
ISO IEA
MGI:5700076 (PMID:26358182) GO_REF:0000107
RGD Ensembl
PMID:26358182
GO_REF:0000107
NCBI chr 8:131,235,714...131,290,359
Ensembl chr 8:122,358,243...122,412,875
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Ube2b
ubiquitin-conjugating enzyme E2B
acts_upstream_of
ISO
MGI:2183933 (PMID:12556476)
RGD
PMID:12556476
NCBI chr10:36,749,365...36,764,335
Ensembl chr10:36,248,438...36,264,665
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Unc5c
unc-5 netrin receptor C
acts_upstream_of
ISO IEA
MGI:1857852 (PMID:18077458) GO_REF:0000107
RGD Ensembl
PMID:18077458
GO_REF:0000107
NCBI chr 2:232,854,352...233,208,482
Ensembl chr 2:230,180,951...230,535,217
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Ybx3
Y box binding protein 3
acts_upstream_of
ISO
MGI:3693011 (PMID:16954378)
RGD
PMID:16954378
NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:165,129,758...165,153,161
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