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ONTOLOGY REPORT - ANNOTATIONS

Term:embryonic heart tube development
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Accession:GO:0035050 term browser browse the term
Definition:The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.


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embryonic heart tube development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apela apelin receptor early endogenous ligand involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:28663440), (PMID:28854362) 		UniProt
Ensembl
RGD		 PMID:28663440 PMID:28854362 GO_REF:0000024 GO_REF:0000107 NCBI chr16:24,694,356...24,703,466
Ensembl chr16:24,694,324...24,703,465 		JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO MGI:1857473|MGI:2687362 (PMID:31219639) RGD PMID:31219639 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Chrd chordin involved_in ISO MGI:2157350 (PMID:17685487) RGD PMID:17685487 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO
IEA 		MGI:2148567 (PMID:18231602)
GO_REF:0000107 		RGD
Ensembl		 PMID:18231602 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ece1 endothelin converting enzyme 1 involved_in IEA
ISO 		GO_REF:0000107
MGI:1857637|MGI:2158947|MGI:2687362 (PMID:30735130) 		Ensembl
RGD		 PMID:30735130 GO_REF:0000107 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Edn1 endothelin 1 involved_in ISO
IEA 		MGI:1857473|MGI:1857637|MGI:2158947|MGI:2687362 (PMID:24875861), (PMID:30735130), (PMID:31219639)
GO_REF:0000107 		RGD
Ensembl		 PMID:24875861 PMID:30735130 PMID:31219639 GO_REF:0000107 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in IEA
ISO 		GO_REF:0000107
MGI:105923|MGI:1857473|MGI:1857637|MGI:2158947|MGI:2179061|MGI:2687362|MGI:3773699 (PMID:20929948), (PMID:24875861), (PMID:30735130), (PMID:31219639) 		Ensembl
RGD		 PMID:20929948 PMID:24875861 PMID:30735130 PMID:31219639 GO_REF:0000107 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO
IEA 		MGI:2176467|MGI:2686864 (PMID:16720879)
GO_REF:0000107 		RGD
Ensembl		 PMID:16720879 GO_REF:0000107 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Foxc1 forkhead box C1 acts_upstream_of_or_within ISO
IEA 		MGI:1347481 (PMID:16678147)
GO_REF:0000107 		RGD
Ensembl		 PMID:16678147 GO_REF:0000107 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1347466 (PMID:16678147) RGD PMID:16678147 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO MGI:2179443|MGI:2386265 (PMID:9136932), (PMID:9136933) RGD PMID:9136932 PMID:9136933 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177 (PMID:14732399) RGD PMID:14732399 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO
IEA 		MGI:2445466 (PMID:14732399), (PMID:22203979)
GO_REF:0000107 		RGD
Ensembl		 PMID:14732399 PMID:22203979 GO_REF:0000107 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Greb1l GREB1 like retinoic acid receptor coactivator acts_upstream_of_or_within ISO
IEA 		(PMID:37852253)
GO_REF:0000107 		RGD
Ensembl		 PMID:37852253 GO_REF:0000107 NCBI chr18:1,392,330...1,629,483
Ensembl chr18:1,392,725...1,628,067 		JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 acts_upstream_of_or_within ISO
IEA 		MGI:2153823 (PMID:9500551)
GO_REF:0000107 		RGD
Ensembl		 PMID:9500551 GO_REF:0000107 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
G Hhex hematopoietically expressed homeobox acts_upstream_of_or_within ISO
IEA 		MGI:2449914 (PMID:15459110)
GO_REF:0000107 		RGD
Ensembl		 PMID:15459110 GO_REF:0000107 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Ift122 intraflagellar transport 122 involved_in ISO (PMID:19000668) RGD PMID:19000668 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO
IEA 		MGI:2684189 (PMID:14500757)
GO_REF:0000107 		RGD
Ensembl		 PMID:14500757 GO_REF:0000107 NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO MGI:105923|MGI:1857637|MGI:2158947|MGI:2179061|MGI:2687362 (PMID:30735130) RGD PMID:30735130 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Nckap1 NCK-associated protein 1 acts_upstream_of_or_within ISO
IEA 		MGI:3578145 (PMID:16831833)
GO_REF:0000107 		RGD
Ensembl		 PMID:16831833 GO_REF:0000107 NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO
IEA 		MGI:1888496 (PMID:15843414)
GO_REF:0000107 		RGD
Ensembl		 PMID:15843414 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Nkx2-6 NK2 homeobox 6 involved_in ISO
IEA 		(PMID:15649947)
GO_REF:0000107
(PMID:9545560) 		RGD
Ensembl		 PMID:9545560 PMID:15649947 GO_REF:0000107 NCBI chr15:44,443,151...44,447,248
Ensembl chr15:44,443,101...44,447,247 		JBrowse link
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO
IEA 		MGI:2158732 (PMID:11311163)
GO_REF:0000107 		RGD
Ensembl		 PMID:11311163 GO_REF:0000107 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Pcnt pericentrin acts_upstream_of_or_within ISO MGI:4340776 (PMID:25220058) RGD PMID:25220058 NCBI chr20:12,190,597...12,278,723
Ensembl chr20:12,191,648...12,278,710 		JBrowse link
G Plxna4 plexin A4 involved_in ISO
IEA 		MGI:105923|MGI:1857637|MGI:2158947|MGI:2179061|MGI:2687362 (PMID:30735130)
GO_REF:0000107 		RGD
Ensembl		 PMID:30735130 GO_REF:0000107 NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 acts_upstream_of_or_within ISO MGI:4849923 (PMID:21302256) RGD PMID:21302256 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO
IEA 		MGI:103559 (PMID:17610846)
GO_REF:0000107 		RGD
Ensembl		 PMID:17610846 GO_REF:0000107 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO MGI:107543 (PMID:17610846) RGD PMID:17610846 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290 		JBrowse link
G Tbx20 T-box transcription factor 20 acts_upstream_of_or_within ISO
IEA 		MGI:3579836|MGI:97350 (PMID:15843414)
GO_REF:0000107 		RGD
Ensembl		 PMID:15843414 GO_REF:0000107 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO
IEA 		MGI:5538565 (PMID:23844108)
GO_REF:0000107 		RGD
Ensembl		 PMID:23844108 GO_REF:0000107 NCBI chr12:42,540,378...42,555,490
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Tmem94 transmembrane protein 94 acts_upstream_of_or_within ISO MGI:6358488 (PMID:30526868) RGD PMID:30526868 NCBI chr10:100,991,523...101,027,046
Ensembl chr10:100,991,573...101,027,394 		JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 acts_upstream_of_or_within ISO
IEA 		MGI:4129326 (PMID:21945076)
GO_REF:0000107 		RGD
Ensembl		 PMID:21945076 GO_REF:0000107 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977 		JBrowse link
embryonic heart tube elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx20 T-box transcription factor 20 involved_in ISO
IEA 		(PMID:15901664)
GO_REF:0000107 		RGD
Ensembl		 PMID:15901664 GO_REF:0000107 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
embryonic heart tube formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand1 heart and neural crest derivatives expressed 1 acts_upstream_of_or_within ISO
IEA 		(PMID:11076684)
GO_REF:0000107 		RGD
Ensembl		 PMID:11076684 GO_REF:0000107 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
embryonic heart tube left/right pattern formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cimap3 ciliary microtubule associated protein 3 acts_upstream_of_or_within ISO
IEA 		MGI:4819764 (PMID:20643351)
GO_REF:0000107 		RGD
Ensembl		 PMID:20643351 GO_REF:0000107 NCBI chr 2:193,475,785...193,493,092
Ensembl chr 2:193,475,782...193,493,139 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in ISO (PMID:15475956) RGD PMID:15475956 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Ift122 intraflagellar transport 122 involved_in ISO (PMID:21209331) RGD PMID:21209331 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458 		JBrowse link
G Invs inversin acts_upstream_of_or_within ISO MGI:1856915 (PMID:9192865) RGD PMID:9192865 NCBI chr 5:62,610,916...62,763,813
Ensembl chr 5:62,610,968...62,763,350 		JBrowse link
G Megf8 multiple EGF-like-domains 8 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:24052814) 		CAFA
Ensembl
RGD		 PMID:24052814 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO
IEA 		MGI:1927227 (PMID:9192865)
GO_REF:0000107 		RGD
Ensembl		 PMID:9192865 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Pitx2 paired-like homeodomain 2 involved_in ISO (PMID:17234970) RGD PMID:17234970 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
embryonic heart tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA 		(PMID:19506109)
GO_REF:0000107 		RGD
Ensembl		 PMID:19506109 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:19609448) 		Ensembl
RGD		 PMID:19609448 GO_REF:0000107 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Megf8 multiple EGF-like-domains 8 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:24052814)
GO_REF:0000024 		Ensembl
RGD
CAFA		 PMID:24052814 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO
IEA 		(PMID:10393122)
GO_REF:0000107 		RGD
Ensembl		 PMID:10393122 GO_REF:0000107 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:9628868) 		UniProt
RGD		 PMID:9628868 GO_REF:0000024 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO
IEA 		(PMID:21305474)
GO_REF:0000107 		RGD
Ensembl		 PMID:21305474 GO_REF:0000107 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO
IEA 		(PMID:15901664)
GO_REF:0000107 		RGD
Ensembl		 PMID:15901664 GO_REF:0000107 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tead1 TEA domain transcription factor 1 acts_upstream_of_or_within ISO MGI:103262|MGI:104904 (PMID:18332127) RGD PMID:18332127 NCBI chr 1:166,791,900...167,010,591
Ensembl chr 1:166,792,628...167,003,369 		JBrowse link
G Tead2 TEA domain transcription factor 2 acts_upstream_of_or_within ISO MGI:101876|MGI:103262 (PMID:18332127) RGD PMID:18332127 NCBI chr 1:95,702,366...95,719,186
Ensembl chr 1:95,703,005...95,719,186 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO
IEA 		MGI:101876|MGI:104904 (PMID:18332127)
GO_REF:0000107 		RGD
Ensembl		 PMID:18332127 GO_REF:0000107 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
heart looping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Ahi1 Abelson helper integration site 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:15,762,485...15,891,213
Ensembl chr 1:15,762,462...15,891,041 		JBrowse link
G Aplnr apelin receptor involved_in ISO
IEA 		(PMID:23603510)
GO_REF:0000107 		RGD
Ensembl		 PMID:23603510 GO_REF:0000107 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G Arl13b ARF like GTPase 13B acts_upstream_of_or_within ISO
IEA 		MGI:3578151 (PMID:22554696)
GO_REF:0000107 		RGD
Ensembl		 PMID:22554696 GO_REF:0000107 NCBI chr11:150,100...217,103
Ensembl chr11:150,955...217,197 		JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 involved_in ISO (PMID:32179481) RGD PMID:32179481 NCBI chr 6:128,239,550...128,275,833
Ensembl chr 6:122,474,756...122,510,854 		JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within ISO (PMID:19004860) RGD PMID:19004860 NCBI chr 1:154,715,151...154,812,955
Ensembl chr 1:154,715,310...154,812,520 		JBrowse link
G Ccdc39 coiled-coil domain 39 molecular ruler complex subunit involved_in ISO
IEA 		(PMID:22693285)
GO_REF:0000107 		RGD
Ensembl		 PMID:22693285 GO_REF:0000107 NCBI chr 2:116,665,651...116,703,354
Ensembl chr 2:116,665,261...116,703,350 		JBrowse link
G Ccdc40 coiled-coil domain 40 molecular ruler complex subunit involved_in ISO
IEA
IBA 		(PMID:22693285)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:22693285 GO_REF:0000033 GO_REF:0000107 NCBI chr10:104,486,748...104,527,284
Ensembl chr10:104,486,748...104,527,243 		JBrowse link
G Cfc1 cripto, FRL-1, cryptic family 1 acts_upstream_of_or_within ISO
IEA 		MGI:2179530 (PMID:10521397)
GO_REF:0000107 		RGD
Ensembl		 PMID:10521397 GO_REF:0000107 NCBI chr 9:36,742,106...36,751,931
Ensembl chr 9:36,739,071...36,751,930 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO MGI:2176158 (PMID:15750185) RGD PMID:15750185 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cluap1 clusterin associated protein 1 acts_upstream_of_or_within ISO MGI:5523142 (PMID:23742838) RGD PMID:23742838 NCBI chr10:11,587,963...11,619,711
Ensembl chr10:11,588,017...11,619,711 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISO (PMID:12730124) RGD PMID:12730124 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dnaaf1 dynein, axonemal, assembly factor 1 involved_in ISO
IEA 		(PMID:19944400), (PMID:19944405)
GO_REF:0000107 		RGD
Ensembl		 PMID:19944400 PMID:19944405 GO_REF:0000107 NCBI chr19:47,624,534...47,652,314
Ensembl chr19:47,624,181...47,652,313 		JBrowse link
G Dnaaf19 dynein axonemal assembly factor 19 involved_in ISO
IEA 		(PMID:22581229)
GO_REF:0000107 		RGD
Ensembl		 PMID:22581229 GO_REF:0000107 NCBI chr10:87,846,327...87,849,959
Ensembl chr10:87,846,357...87,849,757 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 involved_in ISO
IEA 		UniProtKB:Q60838 (PMID:22841628)
GO_REF:0000107 		RGD
Ensembl		 PMID:22841628 GO_REF:0000107 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in ISO
IEA 		UniProtKB:P51141 (PMID:22841628)
GO_REF:0000107 		RGD
Ensembl		 PMID:22841628 GO_REF:0000107 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Eng endoglin involved_in ISO (PMID:10348742), (PMID:19703439) RGD PMID:10348742 PMID:19703439 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO
IEA 		MGI:1857843 (PMID:10411502)
GO_REF:0000107 		RGD
Ensembl		 PMID:10411502 GO_REF:0000107 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Folr1 folate receptor alpha involved_in ISO
IEA 		(PMID:17286298)
GO_REF:0000107 		RGD
Ensembl		 PMID:17286298 GO_REF:0000107 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Foxh1 forkhead box H1 involved_in ISO
IEA 		(PMID:15363409)
GO_REF:0000107 		RGD
Ensembl		 PMID:15363409 GO_REF:0000107 NCBI chr 7:108,387,969...108,391,566
Ensembl chr 7:108,387,969...108,390,049 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (PMID:15310850) RGD PMID:15310850 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177 (PMID:9486664) RGD PMID:9486664 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 acts_upstream_of_or_within ISO
IEA 		MGI:2153823 (PMID:9500551)
GO_REF:0000107 		RGD
Ensembl		 PMID:9500551 GO_REF:0000107 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 acts_upstream_of_or_within ISO
IEA 		MGI:1857639 (PMID:9171826)
GO_REF:0000107 		RGD
Ensembl		 PMID:9171826 GO_REF:0000107 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within ISO
IEA 		MGI:2179429 (PMID:14659802)
GO_REF:0000107 		RGD
Ensembl		 PMID:14659802 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within ISO
IEA 		MGI:3829198 (PMID:18930042)
GO_REF:0000107 		RGD
Ensembl		 PMID:18930042 GO_REF:0000107 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Ift52 intraflagellar transport 52 acts_upstream_of_or_within ISO
IEA 		(PMID:15930098)
GO_REF:0000107 		RGD
Ensembl		 PMID:15930098 GO_REF:0000107 NCBI chr 3:151,672,505...151,696,975
Ensembl chr 3:151,672,493...151,696,980 		JBrowse link
G Ift57 intraflagellar transport 57 acts_upstream_of_or_within ISO
IEA 		MGI:3707373 (PMID:17027958)
GO_REF:0000107 		RGD
Ensembl		 PMID:17027958 GO_REF:0000107 NCBI chr11:51,051,520...51,124,909
Ensembl chr11:51,059,611...51,124,812 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO
IEA 		(PMID:11517919)
GO_REF:0000107 		RGD
Ensembl		 PMID:11517919 GO_REF:0000107 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Kdm2a lysine demethylase 2A acts_upstream_of_or_within ISO (PMID:25463925) RGD PMID:25463925 NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787 		JBrowse link
G Kif3a kinesin family member 3a acts_upstream_of_or_within ISO MGI:2181727 (PMID:10330409) RGD PMID:10330409 NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191 		JBrowse link
G Lbx1 ladybird homeobox 1 acts_upstream_of_or_within ISO
IEA 		MGI:2386948 (PMID:12522123)
GO_REF:0000107 		RGD
Ensembl		 PMID:12522123 GO_REF:0000107 NCBI chr 1:244,083,873...244,085,690
Ensembl chr 1:244,083,873...244,085,690 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (PMID:19795512) RGD PMID:19795512 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO 		GO_REF:0000024
(PMID:16680724) 		UniProt
RGD		 PMID:16680724 GO_REF:0000024 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO
IEA 		(PMID:10393122)
GO_REF:0000107 		RGD
Ensembl		 PMID:10393122 GO_REF:0000107 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Mib1 MIB E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO
IEA 		MGI:3603514 (PMID:16000382)
GO_REF:0000107 		RGD
Ensembl		 PMID:16000382 GO_REF:0000107 NCBI chr18:2,075,309...2,199,774
Ensembl chr18:1,802,519...1,920,689 		JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:166,345,853...166,530,575
Ensembl chr 1:166,345,859...166,471,719
Ensembl chr 1:166,345,859...166,471,719 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO
IEA 		MGI:1927227 (PMID:16510504), (PMID:7628699), (PMID:9192865)
GO_REF:0000107 		RGD
Ensembl		 PMID:7628699 PMID:9192865 PMID:16510504 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO
IEA 		MGI:106676 (PMID:16496285)
GO_REF:0000107 		RGD
Ensembl		 PMID:16496285 GO_REF:0000107 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO
IEA 		UniProtKB:O35516 (PMID:12730124)
GO_REF:0000107 		RGD
Ensembl		 PMID:12730124 GO_REF:0000107 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q01705 (PMID:12730124) 		Ensembl
RGD		 PMID:12730124 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Noto notochord homeobox acts_upstream_of_or_within ISO
IEA 		MGI:3053092 (PMID:17884984)
GO_REF:0000107 		RGD
Ensembl		 PMID:17884984 GO_REF:0000107 NCBI chr 4:117,961,163...117,965,402
Ensembl chr 4:117,961,163...117,965,402 		JBrowse link
G Nphp3 nephrocystin 3 involved_in ISO
IEA 		(PMID:18371931), (PMID:20007846)
GO_REF:0000107 		RGD
Ensembl		 PMID:18371931 PMID:20007846 GO_REF:0000107 NCBI chr 8:104,621,908...104,662,383
Ensembl chr 8:104,621,864...104,662,383 		JBrowse link
G Ovol2 ovo-like zinc finger 2 acts_upstream_of_or_within ISO
IEA 		MGI:3777011 (PMID:17573777)
GO_REF:0000107 		RGD
Ensembl		 PMID:17573777 GO_REF:0000107 NCBI chr 3:131,677,391...131,707,123
Ensembl chr 3:131,677,391...131,708,359 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:21719175) RGD PMID:21719175 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO
IEA 		MGI:109284 (PMID:10557208)
GO_REF:0000107 		RGD
Ensembl		 PMID:10557208 GO_REF:0000107 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:1857796 (PMID:10411502), (PMID:10500184)
GO_REF:0000107
(PMID:11517919) 		RGD
Ensembl		 PMID:10411502 PMID:10500184 PMID:11517919 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smad3 SMAD family member 3 acts_upstream_of_or_within ISO
IEA 		MGI:108051 (PMID:15183723)
GO_REF:0000107 		RGD
Ensembl		 PMID:15183723 GO_REF:0000107 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:11517919)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:11517919 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:2179440 (PMID:17610846)
GO_REF:0000107
(PMID:17610846), (PMID:17655922) 		RGD
Ensembl		 PMID:17610846 PMID:17655922 GO_REF:0000107 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO
IEA 		MGI:2385465|MGI:2386742 (PMID:15929941)
GO_REF:0000107 		RGD
Ensembl		 PMID:15929941 GO_REF:0000107 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Stil STIL, centriolar assembly protein acts_upstream_of_or_within ISO MGI:2152962 (PMID:10385121) RGD PMID:10385121 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO
IEA 		MGI:3512046 (PMID:16155214)
GO_REF:0000107 		RGD
Ensembl		 PMID:16155214 GO_REF:0000107 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Tbx20 T-box transcription factor 20 acts_upstream_of_or_within
involved_in 		ISO
IEA
IBA 		MGI:3579849|MGI:3580099 (PMID:15843407), (PMID:15901664)
GO_REF:0000107
GO_REF:0000033
(PMID:15843409) 		RGD
Ensembl
GO_Central		 PMID:15843407 PMID:15843409 PMID:15901664 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO
IEA 		MGI:2655214|MGI:3769504 (PMID:17460765), (PMID:18723448)
GO_REF:0000107 		RGD
Ensembl		 PMID:17460765 PMID:18723448 GO_REF:0000107 NCBI chr12:42,540,378...42,555,490
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO
IEA 		(PMID:17050629)
GO_REF:0000107 		RGD
Ensembl		 PMID:17050629 GO_REF:0000107 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO
IEA 		MGI:4343479|MGI:4456438 (PMID:20178780)
GO_REF:0000107 		RGD
Ensembl		 PMID:20178780 GO_REF:0000107 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 involved_in ISO
IEA 		(PMID:11440971)
GO_REF:0000107 		RGD
Ensembl		 PMID:11440971 GO_REF:0000107 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO
IEA 		MGI:1857489 (PMID:16291790)
GO_REF:0000107 		RGD
Ensembl		 PMID:16291790 GO_REF:0000107 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO
IEA 		MGI:1298218 (PMID:19795512)
GO_REF:0000107 		RGD
Ensembl		 PMID:19795512 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zic3 Zic family member 3 involved_in
acts_upstream_of_or_within 		ISO (PMID:9354794)
MGI:2180720|MGI:3043027|MGI:97359 (PMID:15384171), (PMID:16496285) 		RGD PMID:9354794 PMID:15384171 PMID:16496285 NCBI chr  X:136,123,662...136,129,627
Ensembl chr  X:136,124,026...136,134,746 		JBrowse link
negative regulation of heart looping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx2 T-box transcription factor 2 involved_in ISO
IEA 		(PMID:15042700)
GO_REF:0000107 		RGD
Ensembl		 PMID:15042700 GO_REF:0000107 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
regulation of heart looping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:162,815,351...162,828,325
Ensembl chr 5:162,815,357...162,828,375 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    multicellular organismal process 9031
      multicellular organism development 5362
        tube development 1358
          embryonic heart tube development 95
            embryonic heart tube dorsal/ventral pattern formation 0
            embryonic heart tube elongation 1
            embryonic heart tube left/right pattern formation 7
            embryonic heart tube morphogenesis + 70
            heart rudiment development + 0
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            circulatory system development 1387
              heart development 750
                embryonic heart tube development 95
                  embryonic heart tube dorsal/ventral pattern formation 0
                  embryonic heart tube elongation 1
                  embryonic heart tube left/right pattern formation 7
                  embryonic heart tube morphogenesis + 70
                  heart rudiment development + 0
paths to the root