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ONTOLOGY REPORT - ANNOTATIONS

Term:SMN-Sm protein complex
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Accession:GO:0034719 term browser browse the term
Definition:A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.
Comment:Note that this complex is sometimes referred to as the 'SMN complex', but it should not be confused with GO:0032797.
Synonyms:broad_synonym: SMN-containing protein complex


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SMN-Sm protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07042226.1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr  X:144,806,986...144,812,552 JBrowse link
G Ddx20 DEAD-box helicase 20 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 2:193,158,761...193,168,484
Ensembl chr 2:193,158,823...193,166,774 		JBrowse link
G Gemin2 gem (nuclear organelle) associated protein 2 part_of ISS
ISO		 GO_REF:0000024
(PMID:18984161)		 UniProt
RGD		 PMID:18984161 GO_REF:0000024 NCBI chr 6:76,706,424...76,721,154
Ensembl chr 6:76,707,523...76,721,153 		JBrowse link
G Gemin4 gem (nuclear organelle) associated protein 4 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431
Ensembl chr10:61,066,425...61,073,431 		JBrowse link
G Gemin5 gem (nuclear organelle) associated protein 5 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr10:42,295,729...42,342,902
Ensembl chr10:42,297,515...42,342,892 		JBrowse link
G Gemin6 gem (nuclear organelle) associated protein 6 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 6:14,786,090...14,790,617
Ensembl chr 6:14,786,070...14,790,612 		JBrowse link
G Gemin7 gem (nuclear organelle) associated protein 7 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 1:79,215,054...79,228,769
Ensembl chr 1:79,214,919...79,224,994 		JBrowse link
G Gemin7l1 gem (nuclear organelle) associated protein 7-like 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:78,269,910...78,270,681
Ensembl chr 4:78,269,888...78,270,669 		JBrowse link
G Gemin8 gem (nuclear organelle) associated protein 8 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr  X:28,259,806...28,278,641
Ensembl chr  X:28,259,793...28,278,663 		JBrowse link
G Smn1 survival of motor neuron 1, telomeric part_of ISS
ISO		 GO_REF:0000024
(PMID:18984161)		 UniProt
RGD		 PMID:18984161 GO_REF:0000024 NCBI chr 2:31,490,018...31,501,065
Ensembl chr 2:31,490,015...31,501,060 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 part_of ISS
ISO		 GO_REF:0000024
(PMID:18984161)		 UniProt
RGD		 PMID:18984161 GO_REF:0000024 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snrpd1 small nuclear ribonucleoprotein D1 polypeptide part_of ISO
IBA		 (PMID:18984161)
GO_REF:0000033		 RGD
GO_Central		 PMID:18984161 GO_REF:0000033 NCBI chr18:1,696,838...1,707,400
Ensembl chr18:1,696,852...1,708,256 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351
Ensembl chr20:78,798,377...78,803,351 		JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide part_of ISO
IBA		 (PMID:18984161)
GO_REF:0000033		 RGD
GO_Central		 PMID:18984161 GO_REF:0000033 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310 		JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G part_of ISO
IBA		 (PMID:18984161)
GO_REF:0000033		 RGD
GO_Central		 PMID:18984161 GO_REF:0000033 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826
Ensembl chr  X:118,812,252...118,819,826 		JBrowse link
G Snrpgl1 small nuclear ribonucleoprotein polypeptide G like 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:87,982,629...87,983,056
Ensembl chr 1:87,982,626...87,983,118
Ensembl chr 4:87,982,626...87,983,118 		JBrowse link
G Strap serine/threonine kinase receptor associated protein part_of ISO
ISS		 (PMID:18984161)
GO_REF:0000024		 RGD
UniProt		 PMID:18984161 GO_REF:0000024 NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828 		JBrowse link
SMN complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx20 DEAD-box helicase 20 part_of ISO
IBA		 (PMID:17178713), (PMID:18984161)
GO_REF:0000033		 RGD
GO_Central		 PMID:17178713 PMID:18984161 GO_REF:0000033 NCBI chr 2:193,158,761...193,168,484
Ensembl chr 2:193,158,823...193,166,774 		JBrowse link
G ENSRNOG00000063060 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 6:84,273,587...84,274,496 JBrowse link
G ENSRNOG00000068876 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 9:112,301,511...112,302,585 JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 located_in ISO (PMID:18093976) RGD PMID:18093976 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Gemin2 gem (nuclear organelle) associated protein 2 part_of ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:17178713), (PMID:18984161)		 UniProt
GO_Central
RGD		 PMID:17178713 PMID:18984161 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:76,706,424...76,721,154
Ensembl chr 6:76,707,523...76,721,153 		JBrowse link
G Gemin4 gem (nuclear organelle) associated protein 4 part_of ISO
IBA		 (PMID:17178713), (PMID:18984161)
GO_REF:0000033		 RGD
GO_Central		 PMID:17178713 PMID:18984161 GO_REF:0000033 NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431
Ensembl chr10:61,066,425...61,073,431 		JBrowse link
G Gemin5 gem (nuclear organelle) associated protein 5 part_of ISO
IBA		 (PMID:17178713), (PMID:18984161), (PMID:20513430)
GO_REF:0000033		 RGD
GO_Central		 PMID:17178713 PMID:18984161 PMID:20513430 GO_REF:0000033 NCBI chr10:42,295,729...42,342,902
Ensembl chr10:42,297,515...42,342,892 		JBrowse link
G Gemin6 gem (nuclear organelle) associated protein 6 part_of ISO
IBA		 (PMID:17178713), (PMID:18984161)
GO_REF:0000033		 RGD
GO_Central		 PMID:17178713 PMID:18984161 GO_REF:0000033 NCBI chr 6:14,786,090...14,790,617
Ensembl chr 6:14,786,070...14,790,612 		JBrowse link
G Gemin7 gem (nuclear organelle) associated protein 7 part_of ISO (PMID:17178713), (PMID:18984161) RGD PMID:17178713 PMID:18984161 NCBI chr 1:79,215,054...79,228,769
Ensembl chr 1:79,214,919...79,224,994 		JBrowse link
G Gemin8 gem (nuclear organelle) associated protein 8 part_of ISO
IBA		 (PMID:16434402), (PMID:17178713), (PMID:18984161)
GO_REF:0000033		 RGD
GO_Central		 PMID:16434402 PMID:17178713 PMID:18984161 GO_REF:0000033 NCBI chr  X:28,259,806...28,278,641
Ensembl chr  X:28,259,793...28,278,663 		JBrowse link
G Glod4 glyoxalase domain containing 4 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898 		JBrowse link
G Smn1 survival of motor neuron 1, telomeric part_of ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:11283611), (PMID:17178713), (PMID:18093976), (PMID:18984161)		 UniProt
GO_Central
RGD		 PMID:11283611 PMID:17178713 PMID:18093976 PMID:18984161 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:31,490,018...31,501,065
Ensembl chr 2:31,490,015...31,501,060 		JBrowse link
G Strap serine/threonine kinase receptor associated protein part_of ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:17178713), (PMID:18984161)		 UniProt
GO_Central
RGD		 PMID:17178713 PMID:18984161 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      cytoplasm 11893
        SMN-Sm protein complex 23
          Lsm-containing SMN-Sm protein complex 0
          SMN complex 13
          SmD-containing SMN-Sm protein complex 0
Path 2
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      intracellular anatomical structure 15189
        cytoplasm 11893
          SMN-Sm protein complex 23
            Lsm-containing SMN-Sm protein complex 0
            SMN complex 13
            SmD-containing SMN-Sm protein complex 0
paths to the root