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ONTOLOGY REPORT - ANNOTATIONS


Term:high-density lipoprotein particle remodeling
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Accession:GO:0034375 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
Synonyms:exact_synonym: HDL remodeling;   HDL remodelling;   high-density lipoprotein particle remodelling
 xref: Reactome:R-HSA-8964058 "HDL remodeling"



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high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISO (PMID:20382126) RGD PMID:20382126 NCBI chr10:95,739,610...95,808,633
Ensembl chr10:95,240,154...95,308,976
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:16556852), (PMID:21481393) RGD PMID:16556852 PMID:21481393 NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA
(PMID:21481393), (PMID:4335615)
GO_REF:0000107
RGD
Ensembl
PMID:4335615 PMID:21481393 GO_REF:0000107 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812), (PMID:8106353) RGD PMID:8106353 PMID:14967812 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO
IEA
(PMID:1935934)
GO_REF:0000107
RGD
Ensembl
PMID:1935934 GO_REF:0000107 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:17438339) RGD PMID:17438339 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
UniProtKB:P08226 (PMID:12401887)
GO_REF:0000107
RGD
Ensembl
PMID:12401887 GO_REF:0000107 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apom apolipoprotein M involved_in ISO
IEA
IBA
(PMID:18006500)
GO_REF:0000107
GO_REF:0000033
(PMID:15793583)
RGD
Ensembl
GO_Central
PMID:15793583 PMID:18006500 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,695,618...3,698,218
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO
IEA
(PMID:10722751), (PMID:12167653), (PMID:15210842), (PMID:4335615)
GO_REF:0000107
RGD
Ensembl
PMID:4335615 PMID:10722751 PMID:12167653 PMID:15210842 GO_REF:0000107 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lipc lipase C, hepatic type involved_in IDA
ISO
IEA
IBA
(PMID:3244012)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:3244012 PMID:8157689 GO_REF:0000033 GO_REF:0000107, RGD:2308770 NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipg lipase G, endothelial type involved_in ISO
IBA
(PMID:19136670)
GO_REF:0000033
RGD
GO_Central
PMID:19136670 GO_REF:0000033 NCBI chr18:70,790,077...70,811,259
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Lpl lipoprotein lipase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:18801741) RGD PMID:18801741 NCBI chr14:82,589,908...82,597,542
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Pltp phospholipid transfer protein involved_in ISO
IBA
(PMID:24369175), (PMID:29883800), (PMID:9132017)
GO_REF:0000033
RGD
GO_Central
PMID:9132017 PMID:24369175 PMID:29883800 GO_REF:0000033 NCBI chr 3:173,994,162...174,011,982
Ensembl chr 3:153,574,825...153,592,647
JBrowse link
G Pnlip pancreatic lipase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:267,760,073...267,797,797
Ensembl chr 1:257,798,581...257,811,654
JBrowse link
G Pnliprp1 pancreatic lipase-related protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:257,867,885...257,883,514
Ensembl chr 1:257,867,885...257,883,514
JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:267,883,906...267,902,572
Ensembl chr 1:257,897,766...257,916,434
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:15210842), (PMID:21481393)
Ensembl
RGD
PMID:15210842 PMID:21481393 GO_REF:0000107 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:31,296,156...31,362,647
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    multicellular organismal process 9002
      plasma lipoprotein particle organization 45
        plasma lipoprotein particle remodeling 30
          high-density lipoprotein particle remodeling 18
            conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle 0
Path 2
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      cellular component organization or biogenesis 7196
        cellular component organization 6911
          protein-containing complex organization 1813
            protein-containing complex remodeling 32
              protein-lipid complex remodeling 30
                plasma lipoprotein particle remodeling 30
                  high-density lipoprotein particle remodeling 18
                    conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle 0
paths to the root