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ONTOLOGY REPORT - ANNOTATIONS

Term:response to type I interferon
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Accession:GO:0034340 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Synonyms:exact_synonym: response to type I IFN


show annotations for term's descendants           Sort by:
response to type I interferon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in ISO
ISS		 (PMID:33239446)
GO_REF:0000024		 RGD
UniProt		 PMID:33239446 GO_REF:0000024 NCBI chr 1:241,428,048...241,429,366
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr13:45,264,404...45,290,737
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO
IEA		 (PMID:22859821)
GO_REF:0000107		 RGD
Ensembl		 PMID:22859821 GO_REF:0000107 NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase involved_in ISO
IEA		 (PMID:28753426)
GO_REF:0000107		 RGD
Ensembl		 PMID:28753426 GO_REF:0000107 NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Shfl shiftless antiviral inhibitor of ribosomal frameshifting involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26735137)		 UniProt
Ensembl
RGD		 PMID:26735137 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:19,408,298...19,414,084
Ensembl chr 8:19,408,333...19,413,971 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in ISO
IEA		 (PMID:24075985)
GO_REF:0000107		 RGD
Ensembl		 PMID:24075985 GO_REF:0000107 NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in ISO
IEA		 (PMID:20807762)
GO_REF:0000107		 RGD
Ensembl		 PMID:20807762 GO_REF:0000107 NCBI chr 1:169,304,772...169,308,615
Ensembl chr 1:159,892,859...159,896,794 		JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:15247905), (PMID:8810287), (PMID:9230084)
(PMID:16873258)		 RGD PMID:8810287 PMID:9230084 PMID:15247905 PMID:16873258 NCBI chr 9:93,758,975...93,825,068
Ensembl chr 9:86,311,032...86,377,034 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Trim56 tripartite motif containing 56 involved_in ISO (PMID:21074459) RGD PMID:21074459 NCBI chr12:19,544,913...19,567,324
Ensembl chr12:19,551,521...19,567,462 		JBrowse link
cellular response to type I interferon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mx2 MX dynamin like GTPase 2 involved_in ISO (PMID:24500530) RGD PMID:24500530 NCBI chr11:50,375,101...50,399,373
Ensembl chr11:36,906,111...36,930,342 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 involved_in ISO (PMID:24525126) RGD PMID:24525126 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO
IEA		 (PMID:28835460)
GO_REF:0000107		 RGD
Ensembl		 PMID:28835460 GO_REF:0000107 NCBI chr 8:118,585,082...118,586,382
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific acts_upstream_of_or_within ISO
IEA		 MGI:3828307 (PMID:19060901)
GO_REF:0000107		 RGD
Ensembl		 PMID:19060901 GO_REF:0000107 NCBI chr 2:177,436,076...177,475,969
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO
IEA		 (PMID:20829348)
GO_REF:0000107		 RGD
Ensembl		 PMID:20829348 GO_REF:0000107 NCBI chr 7:9,042,125...9,047,807
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO
IEA		 (PMID:23386060)
GO_REF:0000107		 RGD
Ensembl		 PMID:23386060 GO_REF:0000107 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Dcst1 DC-STAMP domain containing 1 involved_in ISO
IEA		 (PMID:27782195)
GO_REF:0000107		 RGD
Ensembl		 PMID:27782195 GO_REF:0000107 NCBI chr 2:174,765,203...174,784,023
Ensembl chr 2:174,765,350...174,781,806 		JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 involved_in ISO
IEA		 (PMID:35878012)
GO_REF:0000107		 RGD
Ensembl		 PMID:35878012 GO_REF:0000107 NCBI chr 9:95,333,439...95,362,366
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 involved_in ISO
IEA		 (PMID:35878012)
GO_REF:0000107		 RGD
Ensembl		 PMID:35878012 GO_REF:0000107 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO
IEA		 (PMID:28724761)
GO_REF:0000107		 RGD
Ensembl		 PMID:28724761 GO_REF:0000107 NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO
IEA		 (PMID:30559377)
GO_REF:0000107		 RGD
Ensembl		 PMID:30559377 GO_REF:0000107 NCBI chr15:27,476,659...27,491,134
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO
IEA		 (PMID:23399697)
GO_REF:0000107		 RGD
Ensembl		 PMID:23399697 GO_REF:0000107 NCBI chr 5:155,936,112...155,945,163
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO
IBA		 (PMID:20434986)
GO_REF:0000033		 RGD
GO_Central		 PMID:20434986 GO_REF:0000033 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30078389) RGD PMID:30078389 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA		 (PMID:30078389)
GO_REF:0000107		 RGD
Ensembl		 PMID:30078389 GO_REF:0000107 NCBI chr12:41,439,645...41,463,392
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
IEA
ISS		 (PMID:11909529)
(PMID:11909529), (PMID:12138178)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11909529 PMID:12138178 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO
IEA		 (PMID:29670289)
GO_REF:0000107
(PMID:23972988)		 RGD
Ensembl		 PMID:23972988 PMID:29670289 GO_REF:0000107 NCBI chr 3:166,179,742...166,214,448
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Smim30 small integral membrane protein 30 involved_in ISO (PMID:37656786) RGD PMID:37656786 NCBI chr  X:34,443,180...34,443,365 JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in ISO
IEA		 (PMID:28165510)
GO_REF:0000107		 RGD
Ensembl		 PMID:28165510 GO_REF:0000107 NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:702,495...718,967 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO
IEA		 MGI:3052754 (PMID:18724932)
GO_REF:0000107		 RGD
Ensembl		 PMID:18724932 GO_REF:0000107 NCBI chr 8:118,585,082...118,586,382
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Ttll12 tubulin tyrosine ligase like 12 involved_in ISO
IEA		 (PMID:28011935)
GO_REF:0000107		 RGD
Ensembl		 PMID:28011935 GO_REF:0000107 NCBI chr 7:114,731,890...114,751,237
Ensembl chr 7:114,731,892...114,751,356 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 involved_in ISO (PMID:28165510) RGD PMID:28165510 NCBI chr 4:156,143,770...156,171,292
Ensembl chr 4:154,471,592...154,499,144 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISO
IEA		 (PMID:30559377)
GO_REF:0000107		 RGD
Ensembl		 PMID:30559377 GO_REF:0000107 NCBI chr 5:149,665,467...149,693,127
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein F3 involved_in ISO
IEA		 (PMID:30591559)
GO_REF:0000107		 RGD
Ensembl		 PMID:30591559 GO_REF:0000107 NCBI chr 2:100,266,942...100,300,896
Ensembl chr 2:98,350,588...98,384,606 		JBrowse link
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain involved_in ISO
IEA		 (PMID:21109225)
GO_REF:0000107		 RGD
Ensembl		 PMID:21109225 GO_REF:0000107 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:24882218)
(PMID:27129230)		 RGD PMID:24882218 PMID:27129230 NCBI chr13:45,264,404...45,290,737
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Irf3 interferon regulatory factor 3 acts_upstream_of_or_within ISO (PMID:17618271) RGD PMID:17618271 NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irf7 interferon regulatory factor 7 acts_upstream_of_or_within ISO
IEA		 (PMID:17618271)
GO_REF:0000107		 RGD
Ensembl		 PMID:17618271 GO_REF:0000107 NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor acts_upstream_of_or_within ISO
IEA		 (PMID:22745163)
GO_REF:0000107		 RGD
Ensembl		 PMID:22745163 GO_REF:0000107 NCBI chr 1:96,101,990...96,146,578
Ensembl chr 1:86,964,828...87,009,276 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:16127453), (PMID:20451243) RGD PMID:16127453 PMID:20451243 NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO (PMID:20061403) RGD PMID:20061403 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Rbm47 RNA binding motif protein 47 involved_in ISO
IEA		 (PMID:34160127)
GO_REF:0000107		 RGD
Ensembl		 PMID:34160127 GO_REF:0000107 NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO
IEA
ISS		 (PMID:28273161)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28273161 GO_REF:0000024 GO_REF:0000107 NCBI chr14:82,516,153...82,554,199
Ensembl chr14:78,292,516...78,329,864 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IEA		 (PMID:23910378)
GO_REF:0000107		 RGD
Ensembl		 PMID:23910378 GO_REF:0000107 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO
IEA		 (PMID:27129230)
GO_REF:0000107		 RGD
Ensembl		 PMID:27129230 GO_REF:0000107 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Trim41 tripartite motif-containing 41 involved_in ISO (PMID:29760876) RGD PMID:29760876 NCBI chr10:33,175,213...33,186,472
Ensembl chr10:33,175,213...33,186,694 		JBrowse link
G Trim56 tripartite motif containing 56 involved_in ISO (PMID:29426904) RGD PMID:29426904 NCBI chr12:19,544,913...19,567,324
Ensembl chr12:19,551,521...19,567,462 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO
IEA		 (PMID:24882218)
GO_REF:0000107		 RGD
Ensembl		 PMID:24882218 GO_REF:0000107 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K involved_in ISO
IEA		 (PMID:24882218)
GO_REF:0000107		 RGD
Ensembl		 PMID:24882218 GO_REF:0000107 NCBI chr14:43,011,681...43,077,825
Ensembl chr14:42,658,016...42,718,630 		JBrowse link
G Usp27x ubiquitin specific peptidase 27, X-linked involved_in ISO (PMID:31534008) RGD PMID:31534008 NCBI chr  X:15,123,620...15,126,855
Ensembl chr  X:15,124,596...15,125,912 		JBrowse link
G Usp29 ubiquitin specific peptidase 29 involved_in ISO
IEA		 (PMID:32457395)
GO_REF:0000107		 RGD
Ensembl		 PMID:32457395 GO_REF:0000107 NCBI chr 1:66,874,216...67,097,731
Ensembl chr 1:66,874,017...67,097,686 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 (PMID:19399181)
GO_REF:0000107		 RGD
Ensembl		 PMID:19399181 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000002
(PMID:17618271)
GO_REF:0000033		 InterPro
RGD
GO_Central		 PMID:17618271 GO_REF:0000002 GO_REF:0000033 NCBI chr 3:182,411,665...182,427,604
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc37 cell division cycle 37, HSP90 cochaperone acts_upstream_of_or_within ISO (PMID:16280321) RGD PMID:16280321 NCBI chr 8:27,954,292...27,966,935
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cr2 complement C3d receptor 2 involved_in ISO (PMID:1849076) RGD PMID:1849076 NCBI chr13:109,207,034...109,244,980
Ensembl chr13:106,685,413...106,716,235 		JBrowse link
G ENSRNOG00000065554 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 5:103,321,196...103,322,285 JBrowse link
G ENSRNOG00000068074 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 4:59,549,152...59,549,829 JBrowse link
G ENSRNOG00000070481 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 4:30,960,845...30,961,834 JBrowse link
G Gpr108 G protein-coupled receptor 108 acts_upstream_of_or_within ISO
IEA		 (PMID:37330913)
GO_REF:0000107		 RGD
Ensembl		 PMID:37330913 GO_REF:0000107 NCBI chr 9:2,207,716...2,218,738
Ensembl chr 9:2,120,744...2,132,572 		JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (PMID:31127039) RGD PMID:31127039 NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 involved_in ISO (PMID:27777077) RGD PMID:27777077 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 acts_upstream_of_or_within ISO
IEA		 MGI:3663677 (PMID:28031478)
GO_REF:0000107		 RGD
Ensembl		 PMID:28031478 GO_REF:0000107 NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:196,067,963...196,069,169 		JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:205,481,168...205,482,348
Ensembl chr 1:196,051,537...196,052,741 		JBrowse link
G Ifitm2-ps2 interferon induced transmembrane protein 2, pseudogene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:68,187,131...68,187,808
Ensembl chr13:68,187,366...68,187,854 		JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:20064371)		 GO_Central
RGD		 PMID:20064371 GO_REF:0000033 NCBI chr 1:205,540,649...205,541,758
Ensembl chr 1:196,111,043...196,112,203 		JBrowse link
G Ifitm3-ps1 interferon induced transmembrane protein 3, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:61,233,269...61,233,688
Ensembl chr14:61,233,269...61,233,688 		JBrowse link
G Ifitm3-ps2 interferon induced transmembrane protein 3, pseudogene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:33,137,146...33,137,562
Ensembl chr11:33,137,146...33,138,061 		JBrowse link
G Ifitm6 interferon induced transmembrane protein 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:196,117,043...196,118,315
Ensembl chr 1:196,117,049...196,118,386 		JBrowse link
G Ifna1 interferon, alpha 1 involved_in ISO
IBA		 (PMID:24784232)
GO_REF:0000033		 RGD
GO_Central		 PMID:24784232 GO_REF:0000033 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:103,097,356...103,097,925 		JBrowse link
G Ifna4 interferon, alpha 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052 		JBrowse link
G Ifna4l1 interferon, alpha 4 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,524,733...103,525,302
Ensembl chr 5:103,524,733...103,525,302 		JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,187,852...103,188,430 JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 involved_in ISO
IBA		 (PMID:21854986), (PMID:7665574)
(PMID:14532120), (PMID:23872679), (PMID:27129230)
GO_REF:0000033		 RGD
GO_Central		 PMID:7665574 PMID:14532120 PMID:21854986 PMID:23872679 PMID:27129230 GO_REF:0000033 NCBI chr11:44,211,769...44,238,206
Ensembl chr11:30,725,790...30,749,979 		JBrowse link
G Ifnar2 interferon alpha and beta receptor subunit 2 involved_in ISO
IBA		 (PMID:21854986), (PMID:26424569), (PMID:7665574)
GO_REF:0000033		 RGD
GO_Central		 PMID:7665574 PMID:21854986 PMID:26424569 GO_REF:0000033 NCBI chr11:44,099,574...44,131,941
Ensembl chr11:30,613,767...30,668,124 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO
IBA		 (PMID:18035482), (PMID:33581076)
GO_REF:0000033
(PMID:27129230)		 RGD
GO_Central		 PMID:18035482 PMID:27129230 PMID:33581076 GO_REF:0000033 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifnk interferon kappa involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:54,528,304...54,530,511
Ensembl chr 5:49,732,073...49,734,281 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO
IEA		 (PMID:23633945)
GO_REF:0000107		 RGD
Ensembl		 PMID:23633945 GO_REF:0000107 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (PMID:27129230) RGD PMID:27129230 NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO
IEA		 (PMID:27129230)
GO_REF:0000107		 RGD
Ensembl		 PMID:27129230 GO_REF:0000107 NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO
IEA		 (PMID:7532278), (PMID:8232552)
GO_REF:0000107		 RGD
Ensembl		 PMID:7532278 PMID:8232552 GO_REF:0000107 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G LOC120103158 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,378,576...103,379,147
Ensembl chr 5:103,378,593...103,379,147 		JBrowse link
G LOC120103159 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,407,135...103,407,884
Ensembl chr 5:103,407,283...103,407,837 		JBrowse link
G LOC120103160 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,426,092...103,427,016
Ensembl chr 5:103,426,387...103,426,941 		JBrowse link
G LOC120103161 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,441,204...103,442,180
Ensembl chr 5:103,441,540...103,442,094 		JBrowse link
G LOC120103162 interferon alpha-1-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,455,380...103,455,934
Ensembl chr 5:103,455,380...103,455,934 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO
IEA		 (PMID:23633945)
GO_REF:0000107		 RGD
Ensembl		 PMID:23633945 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO
IBA		 (PMID:28640813)
GO_REF:0000033		 RGD
GO_Central		 PMID:28640813 GO_REF:0000033 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas1b 2-5 oligoadenylate synthetase 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,724,561...35,735,271
Ensembl chr12:35,724,055...35,735,242 		JBrowse link
G Oas1d 2'-5' oligoadenylate synthetase 1D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,648,583...35,658,037
Ensembl chr12:35,648,583...35,657,902 		JBrowse link
G Oas1e 2'-5' oligoadenylate synthetase 1E involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,750,359...35,759,304
Ensembl chr12:35,750,359...35,759,301 		JBrowse link
G Oas1h 2 ' -5 ' oligoadenylate synthetase 1H involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,682,862...35,695,717
Ensembl chr12:35,683,699...35,693,366 		JBrowse link
G Oas1i 2 ' -5 ' oligoadenylate synthetase 1I involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,624,566...35,636,608
Ensembl chr12:35,624,592...35,636,604 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:29117179)		 UniProt
GO_Central
RGD		 PMID:29117179 GO_REF:0000024 GO_REF:0000033 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:41,439,645...41,463,392
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:47,343,551...47,356,509
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Oasl2 2'-5' oligoadenylate synthetase-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:41,710,072...41,722,687
Ensembl chr12:41,709,435...41,722,547 		JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO
IEA		 (PMID:22783022)
GO_REF:0000107		 RGD
Ensembl		 PMID:22783022 GO_REF:0000107 NCBI chr 8:66,377,471...66,432,150
Ensembl chr 8:57,481,573...57,536,192 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO
IBA		 (PMID:23386060)
(PMID:12138178), (PMID:24598055)
GO_REF:0000033		 RGD
GO_Central		 PMID:12138178 PMID:23386060 PMID:24598055 GO_REF:0000033 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in ISO
IEA
IBA		 (PMID:23391734), (PMID:31836668), (PMID:32092142)
GO_REF:0000107
(PMID:24598055), (PMID:28165510)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23391734 PMID:24598055 PMID:28165510 PMID:31836668 PMID:32092142 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:702,495...718,967 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:56,964,617...57,080,523
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO
IEA		 MGI:3052754 (PMID:28351661)
GO_REF:0000107		 RGD
Ensembl		 PMID:28351661 GO_REF:0000107 NCBI chr 8:118,585,082...118,586,382
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Trim65 tripartite motif-containing 65 acts_upstream_of_or_within ISO MGI:6356825 (PMID:28031478) RGD PMID:28031478 NCBI chr10:101,847,822...101,863,052
Ensembl chr10:101,357,937...101,364,971 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:8232552) RGD PMID:8232552 NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    immune system process 3130
      immune response 2236
        innate immune response 1025
          response to type I interferon 94
            cellular response to type I interferon + 88
Path 2
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to biotic stimulus 1943
        response to external biotic stimulus 1894
          response to other organism 1890
            defense response to other organism 1336
              defense response to symbiont 1112
                innate immune response 1025
                  response to type I interferon 94
                    cellular response to type I interferon + 88
paths to the root