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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of amide metabolic process
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Accession:GO:0034249 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.
Synonyms:exact_synonym: negative regulation of amide metabolism;   negative regulation of cellular amide metabolic process



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negative regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgk1 phosphoglycerate kinase 1 involved_in ISO
IEA
(PMID:26942675)
GO_REF:0000107
RGD
Ensembl
PMID:26942675 GO_REF:0000107 NCBI chr  X:75,336,988...75,352,962
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pgk1l1 phosphoglycerate kinase 1 like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:44,487,980...44,489,330
Ensembl chr 2:42,754,639...42,755,856
JBrowse link
negative regulation of amyloid-beta formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO
GO_REF:0000024
(PMID:18429932), (PMID:23467355), (PMID:27030769)
Alzheimers_University_of_Toronto
RGD
PMID:18429932 PMID:23467355 PMID:27030769 GO_REF:0000024 NCBI chr 7:10,342,092...10,362,094
Ensembl chr 7:9,691,449...9,711,425
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
(PMID:24154541)
GO_REF:0000107
(PMID:24259049)
RGD
Ensembl
PMID:24154541 PMID:24259049 GO_REF:0000107 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Bin1 bridging integrator 1 involved_in ISO
IEA
(PMID:27179792)
GO_REF:0000107
RGD
Ensembl
PMID:27179792 GO_REF:0000107 NCBI chr18:24,282,840...24,341,461
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in ISO UniProtKB:P05067 (PMID:20708605) RGD PMID:20708605 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Clu clusterin involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12047389), (PMID:17412999)
GO_REF:0000107
Alzheimers_University_of_Toronto
RGD
Ensembl
PMID:12047389 PMID:17412999 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 involved_in ISO
IEA
(PMID:17553422)
GO_REF:0000107
RGD
Ensembl
PMID:17553422 GO_REF:0000107 NCBI chr10:101,324,378...101,342,373
Ensembl chr10:100,825,426...100,844,462
JBrowse link
G Hap1 huntingtin-associated protein 1 involved_in IMP PMID:22731248 UniProt PMID:22731248 RGD:10047200 NCBI chr10:85,778,267...85,786,553
Ensembl chr10:85,277,890...85,286,126
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
RNAcentral:URS000034B6F5_9606 (PMID:27277332)
GO_REF:0000107
RGD
Ensembl
PMID:27277332 GO_REF:0000107 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Mir103a1 microRNA 103a-1 acts_upstream_of ISO (PMID:27343180) RGD PMID:27343180 NCBI chr10:20,748,474...20,748,559
Ensembl chr10:20,244,412...20,244,497
JBrowse link
G Mir103a2 microRNA 103a-2 acts_upstream_of ISO (PMID:27343180) RGD PMID:27343180 NCBI chr 3:138,963,227...138,963,312
Ensembl chr 3:118,510,194...118,510,279
JBrowse link
G Mir153 microRNA 153 involved_in ISO (PMID:22733824) RGD PMID:22733824 NCBI chr 6:144,306,594...144,306,680
Ensembl chr 6:138,163,595...138,163,681
JBrowse link
G Mir15b microRNA 15b acts_upstream_of ISO (PMID:29961672) RGD PMID:29961672 NCBI chr 2:155,555,178...155,555,275
Ensembl chr 2:153,245,200...153,245,297
JBrowse link
G Mir16-2 microRNA 16-2 acts_upstream_of ISO (PMID:27343180) RGD PMID:27343180 NCBI chr 2:155,555,327...155,555,421
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mir186 microRNA 186 acts_upstream_of ISO (PMID:25100943) RGD PMID:25100943 NCBI chr 2:249,241,650...249,241,735
Ensembl chr 2:246,582,806...246,582,891
JBrowse link
G Mir24-2 microRNA 24-2 acts_upstream_of ISO (PMID:25100943) RGD PMID:25100943 NCBI chr19:40,859,455...40,859,562
Ensembl chr19:23,954,683...23,954,790
JBrowse link
G Mir298 microRNA 298 acts_upstream_of ISO (PMID:31942037) RGD PMID:31942037 NCBI chr 3:183,470,522...183,470,603
Ensembl chr 3:163,052,291...163,052,372
JBrowse link
G Mir29a microRNA 29a acts_upstream_of ISO (PMID:18434550) RGD PMID:18434550 NCBI chr 4:60,617,955...60,618,042 JBrowse link
G Mir29b1 microRNA 29b-1 acts_upstream_of ISO (PMID:18434550) RGD PMID:18434550 NCBI chr 4:60,618,334...60,618,414
Ensembl chr 4:59,650,986...59,651,067
JBrowse link
G Mir29b2 microRNA 29b-2 acts_upstream_of ISO (PMID:18434550) RGD PMID:18434550 NCBI chr13:109,098,831...109,098,911
Ensembl chr13:106,570,367...106,570,456
JBrowse link
G Mir339 microRNA 339 acts_upstream_of ISO (PMID:24352696) RGD PMID:24352696 NCBI chr12:20,391,395...20,391,490
Ensembl chr12:15,277,546...15,277,641
JBrowse link
G Mir361 microRNA 361 involved_in ISO (PMID:31601077) RGD PMID:31601077 NCBI chr  X:82,438,463...82,438,532
Ensembl chr  X:78,246,206...78,246,275
JBrowse link
G Mir455 microRNA 455 acts_upstream_of ISO (PMID:25100943), (PMID:31181293) RGD PMID:25100943 PMID:31181293 NCBI chr 5:81,704,834...81,704,911
Ensembl chr 5:76,689,313...76,689,390
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 acts_upstream_of_or_within ISO
IEA
UniProtKB:P05067-4 (PMID:26094765)
GO_REF:0000107
RGD
Ensembl
PMID:26094765 GO_REF:0000107 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO (PMID:25576397)
(PMID:16554819)
RGD PMID:16554819 PMID:25576397 NCBI chr 8:27,465,538...27,477,016
Ensembl chr 8:19,189,373...19,200,785
JBrowse link
G Prnp prion protein involved_in ISO
IEA
UniProtKB:P12023 (PMID:17573534)
GO_REF:0000107
RGD
Ensembl
PMID:17573534 GO_REF:0000107 NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA
(PMID:24305806), (PMID:27853422)
GO_REF:0000107
RGD
Ensembl
PMID:24305806 PMID:27853422 GO_REF:0000107 NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rtn1 reticulon 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:15286784)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:15286784 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:96,499,137...96,719,340
Ensembl chr 6:90,763,216...90,983,436
JBrowse link
G Rtn2 reticulon 2 involved_in ISO
ISS
IEA
(PMID:15286784)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:15286784 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:88,063,124...88,076,082
Ensembl chr 1:78,935,104...78,948,069
JBrowse link
G Rtn3 reticulon 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:15286784)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:15286784 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:214,041,838...214,098,644
Ensembl chr 1:204,612,675...204,669,275
JBrowse link
G Rtn4 reticulon 4 involved_in ISO
ISS
IEA
(PMID:15286784)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:15286784 GO_REF:0000024 GO_REF:0000107 NCBI chr14:107,651,001...107,698,610
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO
IEA
(PMID:18362153), (PMID:19036982)
(PMID:16174740), (PMID:16407538), (PMID:17855360), (PMID:21989385), (PMID:22621900), (PMID:24001769), (PMID:24523320)
GO_REF:0000107
RGD
Ensembl
PMID:16174740 PMID:16407538 PMID:17855360 PMID:18362153 PMID:19036982 More... GO_REF:0000107 NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
G Spon1 spondin 1 acts_upstream_of_or_within ISO
IEA
(PMID:16227578)
GO_REF:0000107
RGD
Ensembl
PMID:16227578 GO_REF:0000107 NCBI chr 1:177,363,526...177,662,689
Ensembl chr 1:167,928,972...168,228,226
JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 9:55,735,081...55,745,287
Ensembl chr 9:48,237,572...48,253,211
JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO
IEA
(PMID:25691431)
GO_REF:0000107
RGD
Ensembl
PMID:25691431 GO_REF:0000107 NCBI chr 7:1,832,368...1,835,501
Ensembl chr 7:1,246,479...1,250,907
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr10:84,086,317...84,092,673
Ensembl chr10:83,590,071...83,598,620
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:16118219)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:16118219 GO_REF:0000024 GO_REF:0000107 NCBI chr10:102,257,413...102,263,086
Ensembl chr10:101,758,711...101,764,240
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      negative regulation of cellular process 5609
        negative regulation of metabolic process 3146
          negative regulation of amide metabolic process 38
            negative regulation of acetyl-CoA biosynthetic process from pyruvate 2
            negative regulation of amide catabolic process + 0
            negative regulation of amyloid-beta formation 32
            negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA 0
            negative regulation of butyryl-CoA catabolic process to butanol 0
            negative regulation of butyryl-CoA catabolic process to butyrate 0
            negative regulation of ceramide biosynthetic process + 4
            negative regulation of emericellamide biosynthetic process + 0
            negative regulation of ferrichrome biosynthetic process + 0
            negative regulation of gliotoxin biosynthetic process 0
            negative regulation of glutathione biosynthetic process 0
            negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
            negative regulation of penicillin metabolic process + 0
            negative regulation of peptide hormone processing 0
            negative regulation of pseurotin A biosynthetic process 0
            negative regulation of tensidol A biosynthetic process 0
            negative regulation of tensidol B biosynthetic process 0
            negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        negative regulation of biological process 5837
          negative regulation of cellular process 5609
            negative regulation of metabolic process 3146
              negative regulation of amide metabolic process 38
                negative regulation of acetyl-CoA biosynthetic process from pyruvate 2
                negative regulation of amide catabolic process + 0
                negative regulation of amyloid-beta formation 32
                negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA 0
                negative regulation of butyryl-CoA catabolic process to butanol 0
                negative regulation of butyryl-CoA catabolic process to butyrate 0
                negative regulation of ceramide biosynthetic process + 4
                negative regulation of emericellamide biosynthetic process + 0
                negative regulation of ferrichrome biosynthetic process + 0
                negative regulation of gliotoxin biosynthetic process 0
                negative regulation of glutathione biosynthetic process 0
                negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                negative regulation of penicillin metabolic process + 0
                negative regulation of peptide hormone processing 0
                negative regulation of pseurotin A biosynthetic process 0
                negative regulation of tensidol A biosynthetic process 0
                negative regulation of tensidol B biosynthetic process 0
                negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
paths to the root