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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of transcription elongation by RNA polymerase II
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Accession:GO:0034244 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
Synonyms:exact_synonym: negative regulation of RNA elongation from RNA polymerase II promoter;   negative regulation of transcription elongation from RNA polymerase II promoter
 related_synonym: negative regulation of gene-specific transcription elongation from RNA polymerase II promoter
 alt_id: GO:0090041


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negative regulation of transcription elongation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN1 axin 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723 		JBrowse link
G EAPP E2F associated phosphoprotein acts_upstream_of_or_within IDA (PMID:15716352) MGI PMID:15716352 NCBI chr14:34,515,938...34,539,701
Ensembl chr14:34,515,938...34,539,704 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 involved_in IC
IDA 		(PMID:18483487)
(PMID:14580347) 		FlyBase
HGNC-UCL		 PMID:14580347 PMID:18483487 NCBI chr17:45,148,475...45,152,099
Ensembl chr17:45,148,475...45,152,099 		JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IMP (PMID:10490622) UniProt PMID:10490622 NCBI chr 1:244,850,297...244,864,543
Ensembl chr 1:244,840,638...244,864,560 		JBrowse link
G LARP7 La ribonucleoprotein 7, transcriptional regulator involved_in IC (PMID:18483487) FlyBase PMID:18483487 NCBI chr 4:112,637,143...112,657,586
Ensembl chr 4:112,637,077...112,657,696 		JBrowse link
G NELFA negative elongation factor complex member A involved_in
acts_upstream_of_or_within 		IDA
IEA
IBA 		(PMID:12612062) ComplexPortal
Ensembl
GO_Central		 PMID:12612062 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:1,982,723...2,008,974
Ensembl chr 4:1,982,717...2,041,903 		JBrowse link
G NELFB negative elongation factor complex member B involved_in ISS
IBA
IEA
IDA 		(PMID:12612062) UniProt
GO_Central
Ensembl
ComplexPortal		 PMID:12612062 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:137,255,327...137,273,542
Ensembl chr 9:137,255,327...137,273,542 		JBrowse link
G NELFCD negative elongation factor complex member C/D involved_in IDA
IBA 		(PMID:12612062) ComplexPortal
GO_Central		 PMID:12612062 GO_REF:0000033 NCBI chr20:58,981,256...58,995,113
Ensembl chr20:58,981,208...58,995,133 		JBrowse link
G NELFE negative elongation factor complex member E involved_in
acts_upstream_of_or_within 		IEA
ISO
IBA
IDA 		(PMID:21670248)
(PMID:12612062), (PMID:14701750), (PMID:27256882) 		Ensembl
MGI
GO_Central
UniProt		 PMID:12612062 PMID:14701750 PMID:21670248 PMID:27256882 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:31,952,087...31,958,971
Ensembl chr 6:31,952,087...31,959,038 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IDA (PMID:35393539) UniProt PMID:35393539 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha involved_in IDA (PMID:31677974) UniProt PMID:31677974 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183 		JBrowse link
G PPP1R10 protein phosphatase 1 regulatory subunit 10 involved_in IDA (PMID:31677974) UniProt PMID:31677974 NCBI chr 6:30,600,413...30,617,243
Ensembl chr 6:30,600,413...30,618,612 		JBrowse link
G RECQL5 RecQ like helicase 5 involved_in IDA (PMID:23748380) UniProt PMID:23748380 NCBI chr17:75,626,854...75,667,154
Ensembl chr17:75,626,845...75,667,189 		JBrowse link
G RN7SK RNA component of 7SK nuclear ribonucleoprotein involved_in IC (PMID:18483487) FlyBase PMID:18483487 NCBI chr 6:52,995,620...52,995,951
Ensembl chr 6:52,995,620...52,995,950
Ensembl chr 6:52,995,620...52,995,950 		JBrowse link
G RNF168 ring finger protein 168 involved_in IMP (PMID:20550933) UniProt PMID:20550933 NCBI chr 3:196,468,783...196,503,768
Ensembl chr 3:196,468,783...196,503,768 		JBrowse link
G RNF8 ring finger protein 8 involved_in IMP (PMID:20550933) UniProt PMID:20550933 NCBI chr 6:37,353,983...37,394,734
Ensembl chr 6:37,353,979...37,394,734 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SIRT6 sirtuin 6 involved_in
acts_upstream_of_or_within 		ISS
ISO
IEA 		(PMID:31399344) UniProt
UniProt
Ensembl		 PMID:31399344 GO_REF:0000024 GO_REF:0000107 NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566 		JBrowse link
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:58,345,178...58,352,201
Ensembl chr17:58,345,175...58,353,093 		JBrowse link
G TCERG1 transcription elongation regulator 1 involved_in TAS (PMID:20215116) ARUK-UCL PMID:20215116 NCBI chr 5:146,447,330...146,511,961
Ensembl chr 5:146,447,311...146,511,961 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in IDA (PMID:7660122) UniProt PMID:7660122 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,676 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27207
    cellular process 19782
      metabolic process 13524
        biosynthetic process 10164
          macromolecule biosynthetic process 9092
            gene expression 8659
              DNA-templated transcription 3811
                DNA-templated transcription elongation 147
                  transcription elongation by RNA polymerase II 131
                    negative regulation of transcription elongation by RNA polymerase II 22
Path 2
Term Annotations click to browse term
  biological_process 27207
    cellular process 19782
      metabolic process 13524
        primary metabolic process 11719
          nucleobase-containing compound metabolic process 7285
            nucleic acid metabolic process 6663
              RNA metabolic process 6075
                RNA biosynthetic process 5738
                  DNA-templated transcription 3811
                    DNA-templated transcription elongation 147
                      regulation of DNA-templated transcription elongation 109
                        negative regulation of DNA-templated transcription, elongation 25
                          negative regulation of transcription elongation by RNA polymerase II 22
paths to the root