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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of transcription elongation by RNA polymerase II
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Accession:GO:0034244 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
Synonyms:exact_synonym: negative regulation of RNA elongation from RNA polymerase II promoter;   negative regulation of transcription elongation from RNA polymerase II promoter
 related_synonym: negative regulation of gene-specific transcription elongation from RNA polymerase II promoter
 alt_id: GO:0090041

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negative regulation of transcription elongation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN1 axin 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:233,520...295,134
Ensembl chr 5:234,060...290,575 		JBrowse link
G EAPP E2F associated phosphoprotein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr24:11,343,214...11,370,069
Ensembl chr24:11,343,140...11,370,112 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573 		JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:61,258,910...61,264,069
Ensembl chr16:61,260,769...61,261,845 		JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:81,879,532...81,890,684
Ensembl chr25:81,878,111...81,890,701 		JBrowse link
G NELFA negative elongation factor complex member A involved_in
acts_upstream_of_or_within		 IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr27:46,759,742...46,786,835
Ensembl chr27:46,760,707...46,787,090 		JBrowse link
G NELFB negative elongation factor complex member B involved_in ISO (PMID:12612062)
(PMID:19340312), (PMID:24656816), (PMID:25773599)		 ComplexPortal
UniProt		 PMID:12612062 PMID:19340312 PMID:24656816 PMID:25773599 NCBI chr12:914,384...933,921 JBrowse link
G NELFB negative elongation factor complex member B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 Ensembl chr12:913,493...932,063 JBrowse link
G NELFCD negative elongation factor complex member C/D involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:5,146,137...5,159,965
Ensembl chr 2:5,146,575...5,159,883 		JBrowse link
G NELFE negative elongation factor complex member E involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21670248) Ensembl
MGI
TreeGrafter		 PMID:21670248 GO_REF:0000107 GO_REF:0000118 NCBI chr17:40,063,298...40,069,714
Ensembl chr17:40,063,755...40,198,451 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:35393539) UniProt PMID:35393539 NCBI chr25:3,350,798...3,405,040 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr25:3,350,821...3,388,826 JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,862,536...6,866,212
Ensembl chr 1:6,862,540...6,865,855 		JBrowse link
G PPP1R10 protein phosphatase 1 regulatory subunit 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:41,839,504...41,857,228
Ensembl chr17:41,839,833...41,858,470 		JBrowse link
G RECQL5 RecQ like helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,013,100...46,052,713
Ensembl chr16:46,013,092...46,056,167 		JBrowse link
G RNF168 ring finger protein 168 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:90,702,740...90,735,279
Ensembl chr15:90,702,765...90,737,687 		JBrowse link
G RNF8 ring finger protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,754,186...34,787,676
Ensembl chr17:34,751,945...34,787,632 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (PMID:25247314), (PMID:31399344) UniProt PMID:25247314 PMID:31399344 NCBI chr 6:3,924,230...3,932,583
Ensembl chr 6:3,924,230...3,932,590 		JBrowse link
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:35,047,874...35,054,438
Ensembl chr16:35,047,934...35,054,239 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:46,184,621...46,203,065
Ensembl chr22:46,184,756...46,204,428 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19829
    cellular process 19347
      metabolic process 13115
        biosynthetic process 9917
          macromolecule biosynthetic process 8952
            gene expression 8535
              DNA-templated transcription 3356
                DNA-templated transcription elongation 95
                  transcription elongation by RNA polymerase II 81
                    negative regulation of transcription elongation by RNA polymerase II 21
Path 2
Term Annotations click to browse term
  biological_process 19829
    cellular process 19347
      metabolic process 13115
        primary metabolic process 11543
          nucleobase-containing compound metabolic process 7292
            nucleic acid metabolic process 6760
              RNA metabolic process 6208
                RNA biosynthetic process 6013
                  DNA-templated transcription 3356
                    DNA-templated transcription elongation 95
                      regulation of DNA-templated transcription elongation 59
                        negative regulation of DNA-templated transcription, elongation 24
                          negative regulation of transcription elongation by RNA polymerase II 21
paths to the root