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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of transcription elongation by RNA polymerase II
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Accession:GO:0034244 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
Synonyms:exact_synonym: negative regulation of RNA elongation from RNA polymerase II promoter;   negative regulation of transcription elongation from RNA polymerase II promoter
 related_synonym: negative regulation of gene-specific transcription elongation from RNA polymerase II promoter
 alt_id: GO:0090041

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negative regulation of transcription elongation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin1 axin 1 acts_upstream_of_or_within ISO (PMID:10318824), (PMID:19204372) MGI PMID:10318824 PMID:19204372 NCBI chrNW_004955442:16,845,728...16,898,301
Ensembl chrNW_004955442:16,843,152...16,898,430 		JBrowse link
G Eapp E2F associated phosphoprotein acts_upstream_of_or_within ISO (PMID:15716352) MGI PMID:15716352 NCBI chrNW_004955409:26,383,618...26,411,738
Ensembl chrNW_004955409:26,383,732...26,414,568 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (PMID:19303854) MGI PMID:19303854 NCBI chrNW_004955491:4,215,353...4,292,229
Ensembl chrNW_004955491:4,215,298...4,292,235 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:10490622) UniProt PMID:10490622 NCBI chrNW_004955406:8,000,269...8,021,554
Ensembl chrNW_004955406:8,000,269...8,021,554 		JBrowse link
G Nelfa negative elongation factor complex member A involved_in
acts_upstream_of_or_within 		ISO (PMID:12612062)
(PMID:21670248) 		ComplexPortal
MGI		 PMID:12612062 PMID:21670248 NCBI chrNW_004955514:1,162,993...1,173,278
Ensembl chrNW_004955514:1,162,993...1,173,278 		JBrowse link
G Nelfb negative elongation factor complex member B involved_in ISO (PMID:12612062)
(PMID:19340312), (PMID:24656816), (PMID:25773599) 		ComplexPortal
UniProt		 PMID:12612062 PMID:19340312 PMID:24656816 PMID:25773599 NCBI chrNW_004955513:5,248,190...5,261,018
Ensembl chrNW_004955513:5,248,190...5,262,044 		JBrowse link
G Nelfcd negative elongation factor complex member C/D involved_in ISO (PMID:12612062) ComplexPortal PMID:12612062 NCBI chrNW_004955445:597,826...610,134
Ensembl chrNW_004955445:597,826...610,134 		JBrowse link
G Nelfe negative elongation factor complex member E involved_in
acts_upstream_of_or_within 		ISO (PMID:12612062), (PMID:14701750), (PMID:27256882)
(PMID:21670248)
(PMID:31399344) 		UniProt
MGI		 PMID:12612062 PMID:14701750 PMID:21670248 PMID:27256882 PMID:31399344 NCBI chrNW_004955437:467,018...473,084
Ensembl chrNW_004955437:466,690...473,084 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:35393539) UniProt PMID:35393539 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha involved_in ISO (PMID:31677974) UniProt PMID:31677974 NCBI chrNW_004955422:18,076,670...18,079,859
Ensembl chrNW_004955422:18,076,670...18,079,859 		JBrowse link
G Ppp1r10 protein phosphatase 1 regulatory subunit 10 involved_in ISO (PMID:31677974) UniProt PMID:31677974 NCBI chrNW_004955583:621,380...635,595
Ensembl chrNW_004955583:621,092...634,929 		JBrowse link
G Recql5 RecQ like helicase 5 involved_in ISO (PMID:23748380) UniProt PMID:23748380 NCBI chrNW_004955506:6,574,802...6,612,763
Ensembl chrNW_004955506:6,575,408...6,612,186 		JBrowse link
G Rnf168 ring finger protein 168 involved_in ISO (PMID:20550933) UniProt PMID:20550933 NCBI chrNW_004955420:12,656,815...12,676,836
Ensembl chrNW_004955420:12,657,272...12,676,426 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO (PMID:20550933) UniProt PMID:20550933 NCBI chrNW_004955437:5,807,592...5,832,213
Ensembl chrNW_004955437:5,809,082...5,832,057 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO (PMID:17284610) MGI PMID:17284610 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Sirt6 sirtuin 6 involved_in
acts_upstream_of_or_within 		ISO (PMID:25247314), (PMID:31399344)
(PMID:31399344) 		UniProt PMID:25247314 PMID:31399344 NCBI chrNW_004955495:4,641,883...4,650,518
Ensembl chrNW_004955495:4,644,023...4,650,083 		JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit acts_upstream_of_or_within ISO (PMID:21670248) MGI PMID:21670248 NCBI chrNW_004955451:4,682,308...4,688,008
Ensembl chrNW_004955451:4,682,311...4,688,008 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor involved_in ISO (PMID:7660122) UniProt PMID:7660122 NCBI chrNW_004955561:1,573,525...1,578,295
Ensembl chrNW_004955561:1,573,525...1,580,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12628
    cellular process 12059
      metabolic process 7975
        biosynthetic process 5536
          macromolecule biosynthetic process 4812
            gene expression 4478
              DNA-templated transcription 2413
                DNA-templated transcription elongation 73
                  transcription elongation by RNA polymerase II 63
                    negative regulation of transcription elongation by RNA polymerase II 18
Path 2
Term Annotations click to browse term
  biological_process 12628
    cellular process 12059
      metabolic process 7975
        primary metabolic process 6970
          nucleobase-containing compound metabolic process 3928
            nucleic acid metabolic process 3526
              RNA metabolic process 3062
                RNA biosynthetic process 2900
                  DNA-templated transcription 2413
                    DNA-templated transcription elongation 73
                      regulation of DNA-templated transcription elongation 52
                        negative regulation of DNA-templated transcription, elongation 21
                          negative regulation of transcription elongation by RNA polymerase II 18
paths to the root