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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of transcription elongation by RNA polymerase II
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Accession:GO:0034244 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
Synonyms:exact_synonym: negative regulation of RNA elongation from RNA polymerase II promoter;   negative regulation of transcription elongation from RNA polymerase II promoter
 related_synonym: negative regulation of gene-specific transcription elongation from RNA polymerase II promoter
 alt_id: GO:0090041


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negative regulation of transcription elongation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin1 axin 1 acts_upstream_of_or_within ISO
IEA		 (PMID:10318824), (PMID:19204372)
GO_REF:0000107		 RGD
Ensembl		 PMID:10318824 PMID:19204372 GO_REF:0000107 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Eapp E2F-associated phosphoprotein acts_upstream_of_or_within ISO
IEA		 (PMID:15716352)
GO_REF:0000107		 RGD
Ensembl		 PMID:15716352 GO_REF:0000107 NCBI chr 6:72,166,486...72,194,357
Ensembl chr 6:72,170,301...72,193,734 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO
IEA		 MGI:2661097 (PMID:19303854)
GO_REF:0000107		 RGD
Ensembl		 PMID:19303854 GO_REF:0000107 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in ISO
ISS		 (PMID:14580347)
GO_REF:0000024		 RGD
UniProt		 PMID:14580347 GO_REF:0000024 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
ISO		 GO_REF:0000107
(PMID:10490622)		 Ensembl
RGD		 PMID:10490622 GO_REF:0000107 NCBI chr13:92,609,791...92,618,580
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Nelfa negative elongation factor complex member A involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:12612062)
GO_REF:0000033
(PMID:21670248)
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:12612062 PMID:21670248 GO_REF:0000033 GO_REF:0000107 NCBI chr14:76,808,920...76,832,998
Ensembl chr14:76,808,870...76,832,994 		JBrowse link
G Nelfb negative elongation factor complex member B involved_in ISO
IBA
IEA		 (PMID:12612062)
GO_REF:0000033
(PMID:19340312), (PMID:24656816), (PMID:25773599)
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:12612062 PMID:19340312 PMID:24656816 PMID:25773599 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:8,010,883...8,027,403
Ensembl chr 3:8,010,888...8,027,403 		JBrowse link
G Nelfcd negative elongation factor complex member C/D involved_in ISO
IBA
IEA		 (PMID:12612062)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:12612062 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:163,213,765...163,224,886
Ensembl chr 3:163,213,762...163,224,884 		JBrowse link
G Nelfe negative elongation factor complex member E involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:12612062), (PMID:14701750), (PMID:27256882)
GO_REF:0000033
(PMID:31399344)
(PMID:21670248)
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:12612062 PMID:14701750 PMID:21670248 PMID:27256882 PMID:31399344 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,976,512...3,982,389
Ensembl chr20:3,976,518...3,982,355 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO
IEA		 (PMID:35393539)
GO_REF:0000107		 RGD
Ensembl		 PMID:35393539 GO_REF:0000107 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:31677974)		 Ensembl
UniProt
RGD		 PMID:31677974 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31677974)		 UniProt
Ensembl
RGD		 PMID:31677974 GO_REF:0000024 GO_REF:0000107 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611 		JBrowse link
G Recql5 RecQ like helicase 5 involved_in ISO
ISS		 (PMID:23748380)
GO_REF:0000024		 RGD
UniProt		 PMID:23748380 GO_REF:0000024 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652 		JBrowse link
G Rnf168 ring finger protein 168 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20550933)		 UniProt
RGD		 PMID:20550933 GO_REF:0000024 NCBI chr11:68,486,313...68,508,296
Ensembl chr11:68,486,321...68,508,277 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO
ISS		 (PMID:20550933)
GO_REF:0000024		 RGD
UniProt		 PMID:20550933 GO_REF:0000024 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA		 (PMID:17284610)
GO_REF:0000107		 RGD
Ensembl		 PMID:17284610 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO
IEA		 (PMID:25247314), (PMID:31399344)
GO_REF:0000107		 RGD
Ensembl		 PMID:25247314 PMID:31399344 GO_REF:0000107 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit acts_upstream_of_or_within ISO (PMID:21670248) RGD PMID:21670248 NCBI chr10:72,539,323...72,545,582
Ensembl chr10:72,539,382...72,545,831 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor involved_in ISO (PMID:7660122) RGD PMID:7660122 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        biosynthetic process 8654
          macromolecule biosynthetic process 7646
            gene expression 7208
              DNA-templated transcription 3577
                DNA-templated transcription elongation 124
                  transcription elongation by RNA polymerase II 110
                    negative regulation of transcription elongation by RNA polymerase II 19
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        primary metabolic process 10745
          nucleobase-containing compound metabolic process 5888
            nucleic acid metabolic process 5280
              RNA metabolic process 4693
                RNA biosynthetic process 4406
                  DNA-templated transcription 3577
                    DNA-templated transcription elongation 124
                      regulation of DNA-templated transcription elongation 59
                        negative regulation of DNA-templated transcription, elongation 22
                          negative regulation of transcription elongation by RNA polymerase II 19
paths to the root