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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of toll-like receptor 4 signaling pathway
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Accession:GO:0034144 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
Synonyms:exact_synonym: negative regulation of TLR4 signaling pathway;   negative regulation of toll-like receptor 4 signalling pathway



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negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) RGD PMID:23609450 NCBI chr15:86,286,531...86,295,803
Ensembl chr15:79,871,827...79,880,529
JBrowse link
G Bpifb1 BPI fold containing family B, member 1 involved_in ISO
IBA
IEA
(PMID:21900486)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:21900486 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:163,133,151...163,166,420
Ensembl chr 3:142,672,995...142,706,256
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19948740)
UniProt
Ensembl
RGD
PMID:19948740 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:20385881)
UniProt
Ensembl
RGD
PMID:20385881 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO
IEA
(PMID:28609714)
GO_REF:0000107
RGD
Ensembl
PMID:28609714 GO_REF:0000107 NCBI chr16:63,248,833...63,336,441
Ensembl chr16:56,546,207...56,633,743
JBrowse link
G Mir140 microRNA 140 involved_in ISO UniProtKB:O00206 (PMID:30233718), (PMID:30321456) RGD PMID:30233718 PMID:30321456 NCBI chr19:52,375,293...52,375,391
Ensembl chr19:35,465,577...35,465,675
JBrowse link
G Mir200b microRNA 200b involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 5:171,931,495...171,931,589
Ensembl chr 5:166,649,272...166,649,366
JBrowse link
G Mir200c microRNA 200c involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 4:159,209,965...159,210,033 JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:29653364) RGD PMID:29653364 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir708 microRNA 708 involved_in ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:160,011,158...160,011,245
Ensembl chr 1:150,599,876...150,599,963
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISO
IEA
(PMID:18511497)
GO_REF:0000107
RGD
Ensembl
PMID:18511497 GO_REF:0000107 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO
IEA
(PMID:17395780)
GO_REF:0000107
RGD
Ensembl
PMID:17395780 GO_REF:0000107 NCBI chr13:45,673,396...45,699,798
Ensembl chr13:43,121,226...43,147,581
JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO
IEA
(PMID:31281713)
GO_REF:0000107
RGD
Ensembl
PMID:31281713 GO_REF:0000107 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO
IEA
(PMID:28898289)
GO_REF:0000107
RGD
Ensembl
PMID:28898289 GO_REF:0000107 NCBI chr 4:83,152,549...83,208,463
Ensembl chr 4:81,821,989...81,879,100
JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184) RGD PMID:19412184 NCBI chr18:41,481,057...41,498,065
Ensembl chr18:39,294,453...39,311,462
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29407460), (PMID:31134514) RGD PMID:29407460 PMID:31134514 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:28898289) RGD PMID:28898289 NCBI chr 5:84,020,604...84,031,483
Ensembl chr 5:78,999,389...79,022,018
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    immune system process 3130
      negative regulation of immune system process 591
        negative regulation of toll-like receptor 4 signaling pathway 17
Path 2
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to external stimulus 2804
        response to external biotic stimulus 1894
          response to other organism 1890
            defense response to other organism 1336
              defense response to symbiont 1112
                innate immune response 1025
                  regulation of innate immune response 491
                    positive regulation of innate immune response 401
                      activation of innate immune response 329
                        innate immune response-activating signaling pathway 301
                          innate immune response activating cell surface receptor signaling pathway 92
                            cell surface pattern recognition receptor signaling pathway 80
                              cell surface toll-like receptor signaling pathway 74
                                toll-like receptor 4 signaling pathway 64
                                  regulation of toll-like receptor 4 signaling pathway 34
                                    negative regulation of toll-like receptor 4 signaling pathway 17
paths to the root