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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of toll-like receptor signaling pathway
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Accession:GO:0034122 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.
Synonyms:exact_synonym: negative regulation of TLR signaling pathway;   negative regulation of toll-like receptor signalling pathway


show annotations for term's descendants           Sort by:
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO (PMID:16378096) RGD PMID:16378096 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO
IEA		 (PMID:20829348)
GO_REF:0000107		 RGD
Ensembl		 PMID:20829348 GO_REF:0000107 NCBI chr 7:9,042,125...9,047,807
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Gpr108 G protein-coupled receptor 108 involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(PMID:30332431)
GO_REF:0000107		 UniProt
GO_Central
RGD
Ensembl		 PMID:30332431 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:2,207,716...2,218,738
Ensembl chr 9:2,120,744...2,132,572 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:28039360) RGD PMID:28039360 NCBI chr10:55,136,043...55,139,106
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO
IEA		 (PMID:12150927)
GO_REF:0000107		 RGD
Ensembl		 PMID:12150927 GO_REF:0000107 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Irf4 interferon regulatory factor 4 acts_upstream_of_or_within ISO
IEA		 MGI:2387941 (PMID:16236719)
GO_REF:0000107		 RGD
Ensembl		 PMID:16236719 GO_REF:0000107 NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23589304)		 UniProt
Ensembl
RGD		 PMID:23589304 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:116,901,968...117,004,584
Ensembl chr 3:96,447,858...96,548,899 		JBrowse link
G Lrrc14 leucine rich repeat containing 14 involved_in ISO
IBA
IEA
ISS		 (PMID:27426725)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:27426725 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:110,311,384...110,317,757
Ensembl chr 7:108,430,792...108,437,111 		JBrowse link
G Mir140 microRNA 140 IMP RGD PMID:31376096 RGD:329337378 NCBI chr19:52,375,293...52,375,391
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:26041742) RGD PMID:26041742 NCBI chr15:98,587,848...98,587,931
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir19a microRNA 19a involved_in ISO (PMID:26041742) RGD PMID:26041742 NCBI chr15:98,588,131...98,588,212
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in ISO
IEA
IBA
ISS		 (PMID:20829348)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:20829348 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,595,319...3,610,295
Ensembl chr20:3,590,642...3,605,616 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 acts_upstream_of_or_within ISO
IEA		 MGI:5085850 (PMID:22763455)
GO_REF:0000107		 RGD
Ensembl		 PMID:22763455 GO_REF:0000107 NCBI chr 1:205,434,484...205,441,245
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in ISO
IBA		 (PMID:29395066)
GO_REF:0000033		 RGD
GO_Central		 PMID:29395066 GO_REF:0000033 NCBI chr19:45,141,043...45,184,136
Ensembl chr19:28,236,713...28,279,815 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20584979)		 Ensembl
RGD		 PMID:20584979 GO_REF:0000107 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) RGD PMID:20728433 NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Ptgs2os prostaglandin-endoperoxide synthase 2, opposite strand acts_upstream_of_or_within ISO (PMID:23907535) RGD PMID:23907535 NCBI chr13:64,710,129...64,713,837 JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO
IEA		 (PMID:35343654)
GO_REF:0000107		 RGD
Ensembl		 PMID:35343654 GO_REF:0000107 NCBI chr 2:186,950,959...187,018,673
Ensembl chr 2:184,262,371...184,329,823 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B involved_in ISO
IEA		 (PMID:26095358)
GO_REF:0000107		 RGD
Ensembl		 PMID:26095358 GO_REF:0000107 NCBI chr 5:150,228,607...150,250,688
Ensembl chr 5:144,944,636...144,966,720 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISS
ISO
IEA		 GO_REF:0000024
UniProtKB:Q00993|UniProtKB:Q60805 (PMID:18083102)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18083102 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:127,231,468...127,254,806
Ensembl chr 3:106,777,635...106,797,142 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon involved_in ISO (PMID:35343654) RGD PMID:35343654 NCBI chr10:61,082,934...61,120,618
Ensembl chr10:60,584,652...60,671,589 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:22043923) RGD PMID:22043923 NCBI chr10:100,428,826...100,441,693
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Cd300lf Cd300 molecule-like family member F involved_in ISS
ISO		 GO_REF:0000024
(PMID:22043923)		 UniProt
RGD		 PMID:22043923 GO_REF:0000024 NCBI chr10:100,858,924...100,875,111
Ensembl chr10:100,359,943...100,376,041 		JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sarm1 sterile alpha and TIR motif containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:63,867,503...63,890,872
Ensembl chr10:63,369,456...63,392,822 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    immune system process 3130
      negative regulation of immune system process 591
        negative regulation of toll-like receptor signaling pathway 24
          negative regulation of MyD88-dependent toll-like receptor signaling pathway 2
          negative regulation of MyD88-independent toll-like receptor signaling pathway 1
          negative regulation of toll-like receptor 21 signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to external stimulus 2804
        response to external biotic stimulus 1894
          response to other organism 1890
            defense response to other organism 1336
              defense response to symbiont 1112
                innate immune response 1025
                  regulation of innate immune response 491
                    positive regulation of innate immune response 401
                      activation of innate immune response 329
                        innate immune response-activating signaling pathway 301
                          pattern recognition receptor signaling pathway 290
                            toll-like receptor signaling pathway 82
                              regulation of toll-like receptor signaling pathway 38
                                negative regulation of toll-like receptor signaling pathway 24
                                  negative regulation of MyD88-dependent toll-like receptor signaling pathway 2
                                  negative regulation of MyD88-independent toll-like receptor signaling pathway 1
                                  negative regulation of toll-like receptor 21 signaling pathway 0
paths to the root